[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-427628-105":59,"doc-detail-427628-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","cognitive-interventions-for-cancer-related-cognitive-impairment-a-meta-analysis-of-rcts-abstract","COGNITIVE INTERVENTIONS FOR CANCER-RELATED COGNITIVE IMPAIRMENT - A META-ANALYSIS OF RCTS - Abstract","","Cancer-related cognitive impairment (CRCI) affects attention, processing speed, memory, and executive function in survivors across older and younger ages, impairing daily activities and occupational performance. Because pharmacological options show limited efficacy, non-pharmacological cognitive interventions are explored as alternatives with variable effectiveness. This meta-analysis synthesizes evidence from randomized controlled trials evaluating cognitive training interventions for CRCI using standardized neuropsychological and/or self-reported outcomes, with bias assessed via Cochrane’s RoB 2.0 and effects estimated using Hedges’ g. Results from 28 RCTs (n=1,998) show significant gains in multiple cognitive domains and subjective function. Subgroup analyses indicate benefits for cognitive training and meditation, while exercise-based interventions are not significant. Further work is needed to define optimal modalities and long-term effects for clinical guidance.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/cognitive-interventions-for-cancer-related-cognitive-impairment-a-meta-analysis-of-rcts-abstract/427628/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/cognitive-interventions-for-cancer-related-cognitive-impairment-a-meta-analysis-of-rcts-abstract/427628.png","ImageObject",300,407,{"name":92,"@type":93},"Rhys","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-22","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":24},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What cognitive domains improved for people with CRCI after interventions?","Question",{"text":112,"@type":113},"Significant improvements were reported in attention, processing speed, verbal memory, visuospatial memory, executive function, and subjective cognitive function.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the meta-analysis conducted and how were effects estimated?",{"text":117,"@type":113},"A systematic search identified randomized controlled trials assessing cognitive outcomes. Risk of bias used Cochrane’s RoB 2.0, and effect sizes were calculated with Hedges’ g using a random-effects model in CMA 4.0.",{"name":119,"@type":110,"acceptedAnswer":120},"Which intervention types showed significant subgroup effects?",{"text":121,"@type":113},"Cognitive training and meditation produced significant effects, whereas exercise-based interventions did not yield significant benefits.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},427628,1791054084,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":24,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":8,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":81},687207024643,"https://ap-avatar.wpscdn.com/davatar_3d24733baf745e90a7e4bdd5f77d97b2","Innovation in Aging, 2025, Vol. 9, No. S2 857  \nAbstract citation ID: igaf122.2901  \nCOGNITIVE INTERVENTIONS FOR  \nCANCER-RELATED COGNITIVE IMPAIRMENT:  \nA META-ANALYSIS OF RCTS  \nAh Rim Lee1, Moonkyoung Park1, Moira Visovatti2, Kyeongin Cha1, and Misook Jung1, 1. Chungnam National University, Daejeon, Republic of Korea, 2. Eastern Michigan University School of Nursing, Ypsilanti, Michigan, United States  \nCancer-related cognitive impairment (CRCI) is a common challenge among cancer survivors of both older and younger ages, adversely affecting attention, processing speed, memory, and executive function. These deficits often compromise daily activities and occupational performance. Given the limited efficacy of pharmacological treatments, non-pharmacological cognitive interventions have emerged as promising alternatives, although their effectiveness remains variable. This meta-analysis consolidates current evidence on the efficacy of cognitive interventions for enhancing cognitive function in individuals with CRCI. A systematic search of six databases was conducted to identify randomized controlled trials that evaluated cognitive training interventions for CRCI. Studies were included if they assessed cognitive outcomes using standardized neuropsychological tests and/or self-reported measures. The risk of bias was assessed using Cochrane’s RoB 2.0, and effect sizes were calculated using Hedges’ g with a random-effects model in CMA 4.0.  \nA total of 28 RCTs (n = 1,998) were included, with outcomes from both neuropsychological tests and self-reported measures.  \nThe interventions yielded significant improvements in several cognitive domains, including attention (k = 24, g= 0.24), processing speed (k = 19, g= 0.26), verbal memory (k = 22, g= 0.31), visuospatial memory (k = 9, g = 0.33), and executive function (k = 23, g = 0.20) . Additionally, subjective cognitive function showed notable improvement (k = 25, g = 0.40) . Subgroup analyses revealed that cognitive training (k = 19, g = 0.31) and meditation (k = 7, g = 0.32) produced significant effects, while exercise-based intervention did not yield significant benefits. This meta-analysis provides robust evidence supporting beneficial effects of cognitive interventions for managing CRCI. Further research is needed to identify the optimal training modalities and to assess long-term benefits, which guide clinical practices.","cbCaifGR4UyIWMAG","https://ap.wps.com/l/cbCaifGR4UyIWMAG","pdf",769451,"English","# Abstract\n## Background and Rationale\n## Methods\n## Results\n## Subgroup Findings\n## Conclusions and Future Research","[{\"question\":\"What cognitive domains improved for people with CRCI after interventions?\",\"answer\":\"Significant improvements were reported in attention, processing speed, verbal memory, visuospatial memory, executive function, and subjective cognitive function.\"},{\"question\":\"How was the meta-analysis conducted and how were effects estimated?\",\"answer\":\"A systematic search identified randomized controlled trials assessing cognitive outcomes. Risk of bias used Cochrane’s RoB 2.0, and effect sizes were calculated with Hedges’ g using a random-effects model in CMA 4.0.\"},{\"question\":\"Which intervention types showed significant subgroup effects?\",\"answer\":\"Cognitive training and meditation produced significant effects, whereas exercise-based interventions did not yield significant benefits.\"}]","COGNITIVE INTERVENTIONS FOR CANCER-RELATED COGNITIVE IMPAIRMENT - A META-ANALYSIS OF RCTS - Abstract | PDF",1790644390]