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It emphasizes minimizing bias through explicitly documented, advance-planned methods using protocols. The chapter explains Cochrane’s role in preparing, maintaining, and promoting evidence-informed health decisions through high-quality, accessible synthesized research and outlines the organization’s mission and key principles.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/cochrane-handbook-for-systematic-reviews-of-interventions-chapter-1-introduction/137800/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/cochrane-handbook-for-systematic-reviews-of-interventions-chapter-1-introduction/137800.png","ImageObject",300,407,{"name":92,"@type":93},"Olivia Brown","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-09-20","2026-08-23",true,{"@type":102,"interactionType":103,"userInteractionCount":14},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What are systematic reviews designed to do in Cochrane’s approach?","Question",{"text":112,"@type":113},"Systematic reviews collate all evidence that fits pre-specified eligibility criteria to address a specific research question, aiming to support evidence-informed decisions.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How does Cochrane minimize bias in systematic reviews?",{"text":117,"@type":113},"Cochrane emphasizes explicit, systematic methods documented in advance with a protocol to reduce bias and improve transparency.",{"name":119,"@type":110,"acceptedAnswer":120},"What is Cochrane and what is its mission?",{"text":121,"@type":113},"Cochrane is a global independent network that produces credible, accessible systematic reviews. Its mission is to promote evidence-informed health decision-making using high-quality, relevant, accessible synthesized research evidence.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},137800,1787447667,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":14,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":129,"read_time":144},16904993612988,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","Chapter 1: Introduction  \nAuthors: Jackie Chandler, Julian PT Higgins, Jonathan J Deeks, Clare Davenport, Mike J Clarke.  \nThis chapter should be cited as: Chandler J, Higgins JPT, Deeks JJ, Davenport C, Clarke MJ. Chapter 1: Introduction. In: Higgins JPT, Churchill R, Chandler J, Cumpston MS (editors), Cochrane Handbook for Systematic Reviews of Interventions version 5.2.0 (updated June  \n2017), Cochrane, [2017. Available from www.training.cochrane.org/handbook](2017. Available from www.training.cochrane.org/handbook)[ ](2017. Available from www.training.cochrane.org/handbook)Copyright © 2017 The Cochrane Collaboration.  \nThis extract is from Cochrane Handbook for Systematic Reviews of Interventions version 5.2.0. The previous version of this chapter (5.1.0, 2011) is available online at [handbook.cochrane.org](handbook.cochrane.org).  \nAn earlier version (version 5.0.2, 2008) of the Handbook is also published by John Wiley & Sons, Ltd under“The Cochrane Book Series” Imprint, as Higgins JPT, Green S (editors), Cochrane Handbook for Systematic Reviews of Interventions (ISBN 978-0470057964) by John Wiley & Sons Ltd, The Atrium, Southern Gate, Chichester, West Sussex PO19 8SQ, England, Telephone (+44) 1243 779777; Email (for orders and customer service enquiries): [cs-books@wiley.co.uk. Visit](cs-books@wiley.co.uk. Visit) [their Home Page on www.wiley.com](their Home Page on www.wiley.com).  \nThis extract is made available solely for use in the authoring, editing or refereeing of Cochrane Reviews, or for training in these processes by representatives of formal entities of Cochrane. Other than for the purposes just stated, no part of this publication may be reproduced, stored in a retrieval system or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, scanning or otherwise, except under the terms of the Copyright, Designs and Patents Act 1988 or under the terms of a licence issued by the Copyright Licensing Agency Ltd, 90 Tottenham Court Road, London W1T 4LP, UK, without the permission in writing of the copyright holders.  \nPermission to translate part or all of this document must be obtained from the Handbook editors.  \nKey Points  \n• Systematic reviews seek to collate all evidence that fits pre-specified eligibility criteria in order to address a specific research question.  \n• Systematic reviews aim to minimize bias by using explicit, systematic methods documented in advance with a protocol.  \n• Cochrane prepares, maintains and promotes systematic reviews to inform decisions about health and social care (Cochrane Reviews) .  \n• Cochrane Reviews are published in the Cochrane Database of Systematic Reviews in the Cochrane Library.  \n• The Cochrane Handbook for Systematic Reviews of Interventions contains methodological guidance for the preparation and maintenance of Cochrane Intervention Reviews, Overviews of Reviews and Methodology Reviews.  \n• Methodological advice on Cochrane Diagnostic Test Accuracy Reviews can be found in the separate Cochrane Handbook for Diagnostic Test Accuracy Reviews.  \n• Cochrane has developed conduct and reporting standards.  \n1.1 Cochrane  \n1.1.1 What is Cochrane?  \nTrusted evidence. Informed decisions. Better health.  \nCochrane is a global independent network of health practitioners, researchers, patient advocates and others, responding to the challenge of making the vast amounts of evidence generated through research useful for informing decisions about health ([www.cochrane.org](www.cochrane.org)). Previously known as The Cochrane Collaboration, it is a not-forprofit organization where collaborators aim to produce credible, accessible health information that is free from commercial sponsorship and other conflicts of interest.  \nCochrane’s mission is to promote evidence-informed health decision-making by producing high quality, relevant, accessible systematic reviews and other synthesized research evidence. The work of Cochrane is underpinned by a set of 10 key","cbCaikLYOpQ9oMgn","https://ap.wps.com/l/cbCaikLYOpQ9oMgn","pdf",7598775,265,"English","# Chapter 1: Introduction\n## Key Points\n## 1.1 Cochrane\n## 1.1.1 What is Cochrane?\n## 1.1.2 A brief history of Cochrane","[{\"question\":\"What are systematic reviews designed to do in Cochrane’s approach?\",\"answer\":\"Systematic reviews collate all evidence that fits pre-specified eligibility criteria to address a specific research question, aiming to support evidence-informed decisions.\"},{\"question\":\"How does Cochrane minimize bias in systematic reviews?\",\"answer\":\"Cochrane emphasizes explicit, systematic methods documented in advance with a protocol to reduce bias and improve transparency.\"},{\"question\":\"What is Cochrane and what is its mission?\",\"answer\":\"Cochrane is a global independent network that produces credible, accessible systematic reviews. Its mission is to promote evidence-informed health decision-making using high-quality, relevant, accessible synthesized research evidence.\"}]","Cochrane Handbook for Systematic Reviews of Interventions - Chapter 1 - Introduction | PDF",668]