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The document also outlines common superficial and systemic fungal infections and includes a panel discussion on applying sulfonamides to gastrointestinal disease, covering mechanisms, gastric excretion, and therapeutic use across ulcerative colitis, ileitis, biliary tract disease, and bacillary dysentery, followed by general discussion and answers.",{"@graph":69,"@context":116},[70,84,99],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/clinical-notes-common-fungous-diseases-of-man-part-ii-a-panel-discussion-the-application-of-sulfonamides-to-gastrointestinal-disease/570199/",{"url":83,"name":65,"@type":85,"author":86,"headline":65,"publisher":89,"fileFormat":92,"inLanguage":63,"description":67,"dateModified":93,"datePublished":93,"encodingFormat":92,"isAccessibleForFree":94,"interactionStatistic":95},"DigitalDocument",{"name":87,"@type":88},"Grenda","Person",{"url":74,"name":90,"@type":91},"DocShare","Organization","application/pdf","2026-10-13",true,{"@type":96,"interactionType":97,"userInteractionCount":4},"InteractionCounter",{"@type":98},"ViewAction",{"@type":100,"mainEntity":101},"FAQPage",[102,108,112],{"name":103,"@type":104,"acceptedAnswer":105},"What does the document cover under “Clinical Notes”?","Question",{"text":106,"@type":107},"It presents structured clinical conference content including common fungal diseases of man (Part II) and a detailed case discussion involving rectal bleeding episodes, diagnostic evaluation, and management.","Answer",{"name":109,"@type":104,"acceptedAnswer":110},"How are sulfonamides applied in gastrointestinal disease according to the panel discussion?",{"text":111,"@type":107},"The panel outlines action in gastrointestinal disease, gastric excretion in man, and clinical use of specific sulfonamide therapy in conditions such as chronic ulcerative colitis, ileitis, biliary tract disease, and bacillary dysentery.",{"name":113,"@type":104,"acceptedAnswer":114},"What is the general approach to the bleeding case described in the clinical conference?",{"text":115,"@type":107},"The patient is evaluated with laboratory testing and diagnostic procedures, then managed with sedation, bedrest, and low-residue diet; occult blood and parasite/pathogen studies are reported negative, and transfusion is given when hemoglobin continues to fall.","https://schema.org",{"og:url":83,"og:type":118,"og:title":65,"og:site_name":90,"og:description":67},"article",{"robots":120,"canonical":83},"index,follow",{"doc_id":122,"site_id":62},570199,1791879785,{"code":4,"msg":5,"data":125},{"doc_id":122,"user_id":126,"nickname":87,"user_avatar":127,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":128,"file_id":129,"file_url":130,"file_type":131,"file_size":132,"view_count":4,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":133,"language":134,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":135,"faqs":136,"seo_title":137,"seo_description":67,"update_tm":123,"read_time":138},7971474921005,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","feminas  \nSHARP&DOHME  \nU  \nhere is one period of the year when the poor polinosis victim kceps \"friend wife\"busy atthe laundry tub.during the late summer and early fall when his allergic manifestationsdemand a constant supply of fresh handkerchiefs.  \nThe sneczes,wheczes and countless other allergic manifestations of the pollinosis victimmay be relieved symptomatically by the administration of Propadrine'Phenylpropa-nolamine.Hydrochloride,a bronchodilator and local vasoconstrictor.  \nThis synthetic compound produces a prompt and prolonged constriction of engorgedmucous membranes,but rarely causes the unpleasant side-effects associated withephedrine.Its use usually obviates the simultaneous administration of a sedative.'Propadrine'Hydrochloride affords relief in seasonal and perennial hay feverand asthma,and is of value in allergic rhinitis.  \nSupplied in 3s and 34 grain capsules in botles of 25,100 and 500;in elixir(2 gr.per fuidounce)in pint and gallon bottles;in solution(1%and 3%)in 1-ounce and pint bottles;in crystalline powder in L-ounce(14 Gm.)bottles,and in nasal jelly(0.66%)in VL-ounce tubes.Sharp&Dohme,Philadelphia I,Pa.‘PROPADRINE’ydochloidePhenyl-propanol-amine hydrochloride  \nNUMBER 3  \nVOLUME 7  \nCLINICAL CONFERENCE  \nPAGE  \nCASE FORTY-FIVE Patient's complaint:Bleeding from the Bowel..…...............    2CASE FORTY-SIXPatient's complaint:Lumpin Throat and a Choking Sensation...…  …  \n# CLINICAL NOTES\n\nCOMMON FUNGOUS DISEASES OF MAN,PART Ⅱ.......…....  \nSUPERFICIAL FUNGOUS INFECTIONS Tinea Cruris,Ringworm of the Smooth Skin,TineaBarbae,Tinea Capitis .....................  \n5  \nMYCOSES WITH SYSTEMIC INVOLVEMENT Actinomycosis,Blastomycosis,Torulosis,Spor-otrichosis,Mycetoma,Coccidioidomycosis,Rhinosporidiosis,Histoplasmosis  \n9  \n# A PANEL DISCUSSION\n\nTHE APPLICATION OF SULFONAMIDES TO GASTROINTESTINAL DISEASE  \nI.Action of Sulfonamides in Gastrointestinal Disease.....     …………………   15  \nII.Gastric Excretion of Sulfonamides in Man................15  \nII.The Clinical Use of Succinylsulfathiazole in Chronic Ulcerative Colitis.16  \n·  \n17  \nIV.  Late Results in Ulcerative Colitis.........  \n18  \nV.The Use of Sulfonanides in Ileitis..............  \n19  \nVI.Sulfonamide Therapy in Biliary Tract Disease ...    …..  \nVII.  Effects of the Sulfonamides in Bacillary Dysentery ....·..·19  \nGENERAL DISCUSSI0N OF THE USE OF SULFONAMIDES IN GASTROINTESTINALDISORDERS AND ANSWERS T0 QUESTIONS...............................  20  \nPATIENT'S COMPLAINT:This 37year old colored female was first admittedto the medical service five months agocomplaining of bleeding from the bowel.The family history was non-contributory.  \nPast history:She had had no opera-tions,injuries or serious illnesses.Reviewof her symptoms rcvealed that about sixmonths before admission she had had anepisode of nausea,vomiting and abdomi-nal cramps,accompanied by passage of“about two quarts”of blood from the rec-tum.She was treated by her local phy-sician,and recovered uneventfully.Shehad always been constipated,and fre-quently took laxatives and enemas.  \nFor two years she had had nausea,vomiting and abdominal cramps withher menstrual periods.She occasionallyhad to take medicine during these attacksto relieve her pain.After about four daysshe again would be perfectly well untilthe next period.No history of gonococcicinfection or of syphilis could be elicited.  \nPresent illness:Eighteen hours beforeadmission she felt poorly and drank a cupof tea.Following this she suddenly be-came nauseated,andvomited some waterymaterial free of blood.A few hours latershe took an enema,and noticed about acupful of bright red blood in the returns.She felt a little weak and giddy,but wentto bed at the usual hour.Early nextmorning she was awakened with an in-  \nThe patient was apprehensive but wasin no acute distress.She was very pale.The general physical findings were nega-tive except for the abdomen.There wasan indefinite mass in the right lowerquadrant which was slightly tender.Thesigm","cbCaio9U5y9xMcYB","https://ap.wps.com/l/cbCaio9U5y9xMcYB","pdf",3765122,28,"English","# Clinical Notes\n## Common Fungous Diseases of Man, Part II\n## Mycoses with Systemic Involvement\n# A Panel Discussion\n## The Application of Sulfonamides to Gastrointestinal Disease\n## General Discussion and Answers to Questions","[{\"question\":\"What does the document cover under “Clinical Notes”?\",\"answer\":\"It presents structured clinical conference content including common fungal diseases of man (Part II) and a detailed case discussion involving rectal bleeding episodes, diagnostic evaluation, and management.\"},{\"question\":\"How are sulfonamides applied in gastrointestinal disease according to the panel discussion?\",\"answer\":\"The panel outlines action in gastrointestinal disease, gastric excretion in man, and clinical use of specific sulfonamide therapy in conditions such as chronic ulcerative colitis, ileitis, biliary tract disease, and bacillary dysentery.\"},{\"question\":\"What is the general approach to the bleeding case described in the clinical conference?\",\"answer\":\"The patient is evaluated with laboratory testing and diagnostic procedures, then managed with sedation, bedrest, and low-residue diet; occult blood and parasite/pathogen studies are reported negative, and transfusion is given when hemoglobin continues to fall.\"}]","CLINICAL NOTES - COMMON FUNGOUS DISEASES OF MAN, PART II - A PANEL DISCUSSION - THE APPLICATION OF SULFONAMIDES TO GASTROINTESTINAL DISEASE | PDF",71]