[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-457283-105":59,"doc-detail-457283-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","clinical-and-cardiac-magnetic-resonance-imaging-features-for-differentiation-between-acute-myocardial-infarction-with-and-without-obstructive-coronary-arteries-research-findings","Clinical and cardiac magnetic resonance imaging features for differentiation between acute myocardial infarction with and without obstructive coronary arteries - Research findings","","Acute myocardial infarction with nonobstructive coronary arteries (MINOCA) and with obstructive coronary arteries (MIOCA) often face diagnostic difficulty, prompting evaluation of clinical status and cardiac magnetic resonance (CMR) characteristics. Patients with acute MI undergoing CMR and coronary angiography were classified by stenosis degree, then cardiac function and CMR-derived injury metrics were compared across groups. Results show MINOCA has less comorbidity burden, smaller infarct size, higher LV ejection fraction, and strain measures with links to NT-proBNP and infarct extent. CMR strain, infarct size, and NT-proBNP support monitoring and early biomarker identification.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/clinical-and-cardiac-magnetic-resonance-imaging-features-for-differentiation-between-acute-myocardial-infarction-with-and-without-obstructive-coronary-arteries-research-findings/457283/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/clinical-and-cardiac-magnetic-resonance-imaging-features-for-differentiation-between-acute-myocardial-infarction-with-and-without-obstructive-coronary-arteries-research-findings/457283.png","ImageObject",300,407,{"name":92,"@type":93},"Nguyễn Văn Học","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",14,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"How were patients with MINOCA and MIOCA defined in the study?","Question",{"text":113,"@type":114},"Patients with acute MI who underwent CMR imaging and coronary angiography were classified using coronary stenosis degree (>50%). Those meeting the criterion formed the MIOCA group, while the remainder formed the MINOCA group.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What CMR and clinical differences were observed between MINOCA and MIOCA?",{"text":118,"@type":114},"Compared with MIOCA, MINOCA showed lower rates of hypertension, diabetes, wall motion abnormalities, and broader infarct territory. MINOCA also had smaller LV infarct size, lower infarct size rate, higher LV ejection fraction, and higher global peak strain across three directions.",{"name":120,"@type":111,"acceptedAnswer":121},"Which biomarkers or imaging parameters were identified as useful for monitoring or early impairment?",{"text":122,"@type":114},"Strain, infarct size on CMR, and NT-proBNP level were described as reliable for monitoring cardiac dysfunction in MINOCA. GLPS and global circumferential peak strain were highlighted as useful early biomarkers of subclinical impairment.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},457283,1791238097,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":140,"language":141,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":142,"faqs":143,"seo_title":144,"seo_description":67,"update_tm":145,"read_time":146,"preview_page_count":4},1374402739827,"https://ap-avatar.wpscdn.com/avatar/14000c97e7351f1a627?x-image-process=image/resize,m_fixed,w_180,h_180&k=1787885694763230660","Original Article  \nClinical and cardiac magnetic resonance imaging features for differentiation between acute myocardial infarction with and without obstructive coronary arteries  \nLi-Ting Shen1, Zhi-Gang Yang1, Ying-Kun Guo2, Wen-Lei Qian1, Wei-Feng Yan1, Yi-Ning Jiang1, Ke Shi1, Yuan Li1  \n1Department of Radiology, West China Hospital, Sichuan University, Chengdu, China; 2Department of Radiology, West China Second Hospital, Sichuan University, Chengdu, China  \nContributions: (I) Conception and design: LT Shen, ZG Yang, K Shi; (II) Administrative support: YK Guo, ZG Yang; (III) Provision of study materials or patients: LT Shen, WL Qian, WF Yan; (IV) Collection and assembly of data: LT Shen, YN Jiang; (V) Data analysis and interpretation: LT Shen, Y Li; (VI) Manuscript writing: All authors; (VII) Final approval of manuscript: All authors.  \nCorrespondence to: Ke Shi, MD; Yuan Li, MD. Department of Radiology, West China Hospital, Sichuan University, No. 37 Guoxue Lane, Chengdu  \n610041, [China. Email: kshi0110@qq.com](China. Email: kshi0110@qq.com); [dr.liyuan@163.com](dr.liyuan@163.com).  \nBackground: Misdiagnosis often occurs in patients with myocardial infarction (MI) with nonobstructive coronary arteries (MINOCA) and MI with obstructive coronary arteries (MIOCA) . This study explored the  \nclinical and imaging characteristics of patients with MINOCA and MIOCA.  \nMethods: Patients with acute MI (AMI) who underwent cardiac magnetic resonance (CMR) imaging and coronary angiography (CAG) were evaluated. According to coronary stenosis degree (>50%), patients with AMI (n=147) were divided into the MINOCA and MIOCA groups. The cardiac function and CMR characteristics  \nof the two subgroups were emphasized in analysis.  \nResults: The MINOCA group had a lower proportion of patients with hypertension (29.4% vs. 55.2%), hyperlipoproteinemia (9.8% vs. 16.7%), diabetes (19.6% vs. 37.5%), wall motion abnormalities (39.3% vs.  \n75%), complex (both epicardial and subendocardial infarction) infarct type (19.6% vs. 29.2%), and multiple infarct territories (58.8% vs. 77.1%) than did the MIOCA group. Compared with the MIOCA group, the MINOCA group had a smaller left ventricular (LV) infarct size and a lower infarct size rate. The MINOCA group had a higher LV ejection fraction (LVEF) and global peak strain (GPS) in the three directions compared with the MIOCA group. The GPS in three directions were inversely associated with increased N-terminal proB-type natriuretic peptide (NT-proBNP) levels, a greater LV infarct extent, and decreased LVEF in patients with AMI. NT-proBNP level was shown to be an independent determinant of the global longitudinal peakstrain (GLPS) in patients with MINOCA and GPS in three directions in patients with MIOCA. Infarct size  \nwas an independent determinant of GPS in three directions in theMINOCA and MIOCA groups.  \nConclusions: MINOCA had a specific etiology, and patients with MINOCA had better myocardial function than those with MIOCA. Strain, infarct size on CMR imaging, and NT-proBNP level are reliable for monitoring cardiac dysfunction in patients with MINOCA. GLPS and global circumferential peak strain  \nare useful early biomarkers of subclinical impairment in MINOCA.  \nKeywords: Acute myocardial infarction (AMI); myocardial infarction with nonobstructive coronary arteries  \n(MINOCA); magnetic resonance imaging (MRI); late enhancement; feature tracking  \nSubmitted Jun 18, 2025. Accepted for publication Oct 24, 2025. Published online Dec 31, 2025.  \ndoi: 10.21037/qims-2025-1331  \nView this article at: [https://dx.doi.org/10.21037/qims-2025-1331](https://dx.doi.org/10.21037/qims-2025-1331)  \n© AME Publishing Company. Quant Imaging Med Surg 2026;16(1):49 | [https://dx.doi.org/10.21037/qims-2025-1331](https://dx.doi.org/10.21037/qims-2025-1331)  \nPage 2 of 15 Shen et al. CMR features for differentiation between MINOCA and MIOCA  \nIntroduction  \nAcute myocardial infarction (AMI) contributes significantly to mortality","cbCaiuw2vwPPgCvg","https://ap.wps.com/l/cbCaiuw2vwPPgCvg","pdf",847647,15,"English","# Background\n# Methods\n## Study population\n# Results\n# Conclusions\n# Keywords","[{\"question\":\"How were patients with MINOCA and MIOCA defined in the study?\",\"answer\":\"Patients with acute MI who underwent CMR imaging and coronary angiography were classified using coronary stenosis degree (\\u003e50%). Those meeting the criterion formed the MIOCA group, while the remainder formed the MINOCA group.\"},{\"question\":\"What CMR and clinical differences were observed between MINOCA and MIOCA?\",\"answer\":\"Compared with MIOCA, MINOCA showed lower rates of hypertension, diabetes, wall motion abnormalities, and broader infarct territory. MINOCA also had smaller LV infarct size, lower infarct size rate, higher LV ejection fraction, and higher global peak strain across three directions.\"},{\"question\":\"Which biomarkers or imaging parameters were identified as useful for monitoring or early impairment?\",\"answer\":\"Strain, infarct size on CMR, and NT-proBNP level were described as reliable for monitoring cardiac dysfunction in MINOCA. GLPS and global circumferential peak strain were highlighted as useful early biomarkers of subclinical impairment.\"}]","Clinical and cardiac magnetic resonance imaging features for differentiation between acute myocardial infarction with and without obstructive coronary arteries - Research findings | PDF",1790748788,38]