[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-342645-105":59,"doc-detail-342645-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","chylous-ascites-associated-with-advanced-pancreatic-cancer-that-improved-with-appropriate-treatment-a-case-report","Chylous Ascites Associated with Advanced Pancreatic Cancer That Improved with Appropriate Treatment - A Case Report","","Chylous ascites is a rare, high-triglyceride form of ascites originating from thoracoabdominal lymph nodes, often complicating conditions including pancreatic cancer. During chemotherapy, progressive ascites can worsen performance status, hinder treatment delivery, and lead to poor prognosis. A rare case of chylous ascites accompanied by advanced pancreatic cancer showed discordance between tumor shrinkage and ascites accumulation. Prompt biochemical testing enabled diagnosis. Octreotide treatment rapidly improved both ascites and overall condition, allowing continuation of pancreatic cancer chemotherapy.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/chylous-ascites-associated-with-advanced-pancreatic-cancer-that-improved-with-appropriate-treatment-a-case-report/342645/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/chylous-ascites-associated-with-advanced-pancreatic-cancer-that-improved-with-appropriate-treatment-a-case-report/342645.png","ImageObject",300,407,{"name":92,"@type":93},"Olivia Brown","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-28","2026-09-22",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What problem did the case report describe during chemotherapy for advanced pancreatic cancer?","Question",{"text":112,"@type":113},"The patient developed chylous ascites with high triglyceride content, which accumulated despite tumor shrinkage and worsened symptoms and performance status.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the chylous ascites diagnosed in the case?",{"text":117,"@type":113},"Chylous ascites was promptly diagnosed using biochemical tests after the clinical discrepancy between pancreatic cancer response and ascites accumulation.",{"name":119,"@type":110,"acceptedAnswer":120},"What treatment was used for chylous ascites, and what was the result?",{"text":121,"@type":113},"The patient was treated with octreotide, which rapidly improved the ascites and the patient’s general condition, enabling continuation of chemotherapy.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},342645,1790615161,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":29,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144},16904993612988,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","Case Report  \nChylous Ascites Associated with Advanced Pancreatic Cancer That Improved with Appropriate Treatment: A Case Report  \nHiroo Imai 1,2, Ken Saijo 1,2, Noriko Takenaga 2, Keigo Komine 1,2, Kota Ouchi 1,2, Yuki Kasahara 1,2, Shiori Ishikawa 1,2, Keiju Sasaki 1,2, Yuya Yoshida 1,2, Hidekazu Shirota 1,2, Masanobu Takahashi 1,2 and Chikashi Ishioka 1,2, *  \nCitation: Imai, H.; Saijo, K.; Takenaga, N.; Komine, K.; Ouchi, K.; Kasahara, Y.; Ishikawa, S.; Sasaki, K.; Yoshida, Y.; Shirota, H.; et al. Chylous Ascites Associated with Advanced Pancreatic Cancer That Improved with Appropriate Treatment: A Case Report. Curr. Oncol. 2024, 31, 1477–1482. [https://doi.org/10.3390/](https://doi.org/10.3390/)[ ](https://doi.org/10.3390/)curroncol31030112  \nReceived: 3 February 2024  \nRevised: 9 March 2024  \nAccepted: 11 March 2024  \nPublished: 12 March 2024  \nCopyright: © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ([https://](https://)[ ](https://)[creativecommons.org/licenses/by/](creativecommons.org/licenses/by/)[ ](creativecommons.org/licenses/by/)[4.0/](4.0/)) .  \n1 Department of Medical Oncology, Tohoku University Hospital, Sendai 980-8547, Japan; [hiroo.imai.d8@tohoku.ac.jp](hiroo.imai.d8@tohoku.ac.jp) (H.I.); [ken.saijo.d6@tohoku.ac.jp](ken.saijo.d6@tohoku.ac.jp) (K.S.); [keigo.komine.e7@tohoku.ac.jp](keigo.komine.e7@tohoku.ac.jp) (K.K.); [kota.ouchi.b3@tohoku.ac.jp](kota.ouchi.b3@tohoku.ac.jp) (K.O.); [yuki.kasahara.d8@tohoku.ac.jp](yuki.kasahara.d8@tohoku.ac.jp) (Y.K.); [shiori.takahashi.q7@dc.tohoku.ac.jp](shiori.takahashi.q7@dc.tohoku.ac.jp) (S.I.); [keiju.sasaki.d6@tohoku.ac.jp](keiju.sasaki.d6@tohoku.ac.jp) (K.S.); [yuya.yoshida.c1@tohoku.ac.jp](yuya.yoshida.c1@tohoku.ac.jp) (Y.Y.); [hidekazu.shirota.e1@tohoku.ac.jp](hidekazu.shirota.e1@tohoku.ac.jp) (H.S.); [masanobu.takahashi.a7@tohoku.ac.jp](masanobu.takahashi.a7@tohoku.ac.jp) (M.T.)  \n2 Department of Clinical Oncology, Tohoku University Graduate School of Medicine, Sendai 980-8575, Japan; [noriko.takenaga.b3@tohoku.ac.jp](noriko.takenaga.b3@tohoku.ac.jp)  \n* Correspondence: [chikashi@tohoku.ac.jp](chikashi@tohoku.ac.jp); Tel.: +81-227178543  \nAbstract: Chylous ascites is a rare form of ascites with high triglyceride content arising from the thoracoabdominal lymph nodes in the peritoneal cavity due to various benign or malignant etiologies, including pancreatic cancer. During cancer chemotherapy, the accumulation of ascites can lead to the deterioration of the patient’s general condition, making chemotherapy administration difficult, and resulting in a poor prognosis. We encountered a rare case of chylous ascites complicated by advanced pancreatic cancer. The patient presented with a discrepancy between the shrinkage of the pancreatic cancer and the accumulation of ascites. Therefore, we were able to promptly diagnose chylous ascites by performing biochemical tests. The patient was treated with octreotide, reportedly effective in treating chylous ascites, which rapidly improved the chylous ascites and general condition of the patient, allowing the patient to continue chemotherapy for pancreatic cancer. Therefore, physicians should consider the possibility of chylous ascites when clinically unexplained ascites are observed inpatients with advanced cancer. The investigation and treatment of chylous ascites should be initiated as soon as possible.  \nKeywords: chylous ascites; octreotide; pancreatic cancer; chemotherapy  \n1. Introduction  \nChylous ascites is a rare form of ascites with high triglyceride content arising from the thoracoabdominal lymph nodes in the peritoneal cavity due to various benign or malignant etiologies [1] . It occurs in approximately 1 in 20,000 patients and is predominantly caused by surgical complications, trauma, or cirrhosis [2] . A few cases of chylous ascites are associated with solid malignancies, ","cbCaioBDWAhGvRvc","https://ap.wps.com/l/cbCaioBDWAhGvRvc","pdf",1182563,"English","# Introduction\n# Case Presentation\n## Diagnosis\n## Treatment and Outcome","[{\"question\":\"What problem did the case report describe during chemotherapy for advanced pancreatic cancer?\",\"answer\":\"The patient developed chylous ascites with high triglyceride content, which accumulated despite tumor shrinkage and worsened symptoms and performance status.\"},{\"question\":\"How was the chylous ascites diagnosed in the case?\",\"answer\":\"Chylous ascites was promptly diagnosed using biochemical tests after the clinical discrepancy between pancreatic cancer response and ascites accumulation.\"},{\"question\":\"What treatment was used for chylous ascites, and what was the result?\",\"answer\":\"The patient was treated with octreotide, which rapidly improved the ascites and the patient’s general condition, enabling continuation of chemotherapy.\"}]","Chylous Ascites Associated with Advanced Pancreatic Cancer That Improved with Appropriate Treatment - A Case Report | PDF",1790047534,15]