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Seventy-two women were enrolled after alopecia onset on or after stopping chemotherapy within the prior 6 months, using a self-prepared questionnaire and the Dermatology Life Quality Index (DLQI). Alopecia emerged soon after the first course in 62.5%, while 97.2% reported quality-of-life impact, with median DLQI 6.5. Working status predicted worse outcomes.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/chemotherapy-induced-alopecia-in-breast-cancer-patients-a-monocentric-prospective-study/332438/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/chemotherapy-induced-alopecia-in-breast-cancer-patients-a-monocentric-prospective-study/332438.png","ImageObject",300,407,{"name":92,"@type":93},"Theodore","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-05","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":34},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the study’s aim regarding alopecia in breast cancer patients?","Question",{"text":112,"@type":113},"To evaluate how chemotherapy induced alopecia influences patients’ quality of life, which clinicians often underestimate.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How many patients were included and how was alopecia-related quality of life measured?",{"text":117,"@type":113},"Seventy-two breast cancer patients were included. Quality of life was assessed using the Dermatology Life Quality Index (DLQI) based on a validated Arabic version and a self-prepared questionnaire.",{"name":119,"@type":110,"acceptedAnswer":120},"Which patient factors were associated with worse quality of life in the results?",{"text":121,"@type":113},"Working status significantly predicted poorer quality of life, and patients who did not undergo mastectomy were more bothered by hair loss than those who had radical surgery.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},332438,1790219004,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":34,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},7971461740886,"https://ap-avatar.wpscdn.com/davatar_3d24733baf745e90a7e4bdd5f77d97b2","Breast Disease 43 (2024) 251–255 251  \nDOI 10.3233/BD-240019 IOS Press  \nChemotherapy induced alopecia in breast cancer patients: A monocentric prospective study  \nWala Ben Kridis∗ , Olfa Boudawara and Afef Khanfir  \nDepartment of Medical Oncology, Habib Bourguiba Hospital, University ofSfax, Sfax, Tunisia  \nAbstract.  \nINTRODUCTION: Alopecia is one of the main adverse events of chemotherapy in breast cancer. However, its impact is often ignored and underestimated by clinicians. Our aim was to evaluate the quality of life of breast cancer patients with chemotherapy induced alopecia.  \nMETHODS: We conducted a prospective study including 72 breast cancer patients who developed alopecia on or after stopping chemotherapy in the last 6 months. Clinical information and characteristics of alopecia were assessed using a self-prepared questionnaire. DLQI score was used to evaluate patients’ quality of life.  \nRESULTS: We interviewed a total of 72 women with a mean age of 53.5 ± 6 years. Alopecia appeared soon after the first course in 62.5%. All patients actively tried to hide induced hair fall (either by a hat in 6.9% or by a headscarf in 93.1%). Quality of life was impacted in 97.2% of patients with a median DLQI score of 6.5 . Women who did not underwent mastectomy were significantly more bothered by hair loss than those who had radical surgery (78.1% vs 55%, p = 0.04) . Working status was a significant predictor factor of a bad quality of life due to alopecia (100% in working women vs 58.3% in homemaker or retired patients, p = 0.006) . CONCLUSION: Chemotherapy induced alopecia had a negative impact on quality of life of patients with breast cancer, especially in working women and those who did not have radical surgery. Prior wearing of headscarves did not impact significantly the DLQI score.  \nKeywords: Chemotherapy induced alopecia, breast cancer, quality of life  \n1. Introduction  \nAlopecia is a wide common side effect of chemotherapy. The estimated incidence of chemotherapyinduced hair loss is 65%[1] . Drugs used in breast cancer such as anthracyclines are the most commonly incriminated agents in causing hair loss in more than 90% [1] . Chemotherapy combination, mainly cyclophosphamide and anthracyclines, increases the risk of alopecia compared to single agents [1,2] . Hair loss is the most frequently reported skin side effect induced by anti-cancer treatment, accounting for 91.9% of patients with breast cancer [3] . The use of preventative strategies against chemotherapy induced alopecia  \n*  \nCorresponding author: Dr Wala Ben Kridis, Department of Oncology, Habib Bourguiba Hospital, Sfax 3029, Tunisia. Tel.: +216 94492526; [E-mail: walabenkridis@yahoo.fr](E-mail: walabenkridis@yahoo.fr).  \nvary across the globe such us the uptake of scalp cooling. Vasoconstriction leads to reduced blood flow to the hair follicles.  \nDespite its high prevalence, alopecia is often neglected by clinicians who are more interested by the treatment response [4] . Thus, its impact on quality of life is underestimated leading to a lack of supportive care strategies.  \nWe aimed to detect patients with breast cancer at higher risk of distress after chemotherapy induced alopecia.  \n2. Methods  \nThis prospective study investigated quality of life in women with alopecia induced by chemotherapy for breast cancer. Patients were recruited from the department of medical oncology at Habib Bourguiba Hospital in Sfax, Tunisia.  \n0888-6008 © 2024 – The authors. Published by IOS Press. This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (CC BY-NC 4 .0) .  \n252 W. Ben Kridis et al. / Chemotherapy induced alopecia in breast cancer patients  \nPatients with breast cancer patients who developed alopecia on or after stopping chemotherapy in the last 6 months were included. We collected data of patients with breast cancer (regardless of stage) suffering from chemotherapy induced alopecia during the month of October ","cbCaipb2ldGnnesj","https://ap.wps.com/l/cbCaipb2ldGnnesj","pdf",52200,"English","# Introduction\n# Methods\n# Results\n# Conclusion","[{\"question\":\"What was the study’s aim regarding alopecia in breast cancer patients?\",\"answer\":\"To evaluate how chemotherapy induced alopecia influences patients’ quality of life, which clinicians often underestimate.\"},{\"question\":\"How many patients were included and how was alopecia-related quality of life measured?\",\"answer\":\"Seventy-two breast cancer patients were included. Quality of life was assessed using the Dermatology Life Quality Index (DLQI) based on a validated Arabic version and a self-prepared questionnaire.\"},{\"question\":\"Which patient factors were associated with worse quality of life in the results?\",\"answer\":\"Working status significantly predicted poorer quality of life, and patients who did not undergo mastectomy were more bothered by hair loss than those who had radical surgery.\"}]","Chemotherapy induced alopecia in breast cancer patients - A monocentric prospective study | PDF",1789998192,13]