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Patient features, microbiological cultures, length of stay, ICU transfers, and all-cause mortality were assessed. Early clinical stability (day 3 criteria) was reached by 48.9%, with 88.9% discharged home, while 3.2% required ICU transfer and 10.9% 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\nORIGINAL STUDY  \nCharacteristics and Outcomes of Cancer Patients Admitted to the Hospital With CommunityAcquired Pneumonia  \nAnoud Al-Saleh *, Dana Hassouneh, Sara Dhaydel, Nour Faqeer  \nDepartment of Pharmacy, King Hussein Cancer Center, Amman, Jordan  \nAdvances in Knowledge  \n• This study provides novel insights into the clinical characteristics and outcomes of cancer patients hospitalised with communityacquired pneumonia (CAP).  \n• By evaluating a relatively large cohort of patients, the study highlights the prevalence of breast cancer within this population and the signiﬁcant rate of microbiological positivity.  \n• The study identiﬁes metrics for early clinical stability and hospital outcomes, aiding in risk stratiﬁcation and optimising discharge planning to improve patient management and reduce readmissions.  \n• This study's ﬁndings underscore the importance of conducting further research and exploring potential interventions to improve outcomes for cancer patients with CAP.  \nApplications to Patient Care  \n• This study underscores the importance of monitoring and providing tailored treatment for cancer patients diagnosed with CAP.  \n• The identiﬁcation of indicators for early clinical stability can guide clinicians in making informed decisions about the appropriate site for patient care, potentially reducing the need for hospital admissions and the associated complications.  \n• This study suggests that clinically stable patients meeting early stability criteria may be safely transitioned to outpatient care, reducing hospital stays and improving overall outcomes.  \n• These ﬁndings can enhance the clinical management of CAP in cancer patients, leading to improved outcomes and more eﬃcient use of healthcare resources.  \nABSTRACT  \nObjectives: Community-acquired pneumonia (CAP) poses a signiﬁcant risk of complications in cancer patients. However, limited studies have evaluated hospitalised cancer patients with CAP. This study aimed to evaluate the characteristics and outcomes of cancer patients hospitalised with CAP. Methods: This retrospective study included adult cancer patients diagnosed with CAP admitted at the King Hussein Cancer Center, Jordan, from January 2021 to August 2022, following the Infectious Diseases Society of America guidelines. Patient characteristics, microbiological cultures, length of hospital stay, intensive care unit (ICU) transfers and all-cause mortality were recorded. Early clinical stability was deﬁned as temperature 􀀔37.8°C, heart rate 􀀔100 beats/min, respiratory rate 􀀔24 breathes/min, systolic blood pressure 􀀕90 mmHg and oxygen saturation 􀀕90% while breathing room air on the third day of admission. Results: A total of 632 cancer patients were admitted with CAP. The mean age was 60 􀀆 13.9 years, with 55.2% of the patients being male. Breast cancer was the most prevalent malignancy (22.9%), and 48.6% had received cancer-related treatment within the last 2 months. Positive blood and sputum cultures were detected in 12.4% and 30.0% of patients, respectively. Early clinical stability was achieved in 48.9%, and 88.9% of those patients were discharged after a median stay of 6 days (range: 1–48). Among the included patients, 3.2% required ICU transfer, and 10.9% died. Conclusions: Early clinical stability was achieved in approximately half of the patients, most of whom were discharged home. Future research should identify interventions to improve clinical outcomes for cancer patients with CAP.  \nKeywords: Pneumonia; Community-Acquired Infections; Immunocompromised; Cancer; Hospitalisation; Jordan  \nReceived 2 July 2024; revised 8 October 2024; accepted 23 October 2024.  \nAvailable online 20 March 2025  \n* Corresponding author.  \nE-mail address: AA.15096@KHCC.JO, [anoudaltamimi96@gmail.com](anoudaltamimi96@gmail.com) (A. Al-Saleh).  \n[https://doi.org/10.18295/squmj.10.2024.058](htt","cbCaif23zUyDFBUi","https://ap.wps.com/l/cbCaif23zUyDFBUi","pdf",271131,"English","# Introduction\n# Objectives, Methods, Results, and Conclusions\n# Keywords","[{\"question\":\"What was the main objective of the study?\",\"answer\":\"To evaluate the clinical characteristics and outcomes of hospitalized cancer patients with community-acquired pneumonia.\"},{\"question\":\"How did the study define early clinical stability?\",\"answer\":\"Early clinical stability was defined using day-3 thresholds for temperature, heart rate, respiratory rate, systolic blood pressure, and oxygen saturation while breathing room air.\"},{\"question\":\"What were the key outcomes for the patients?\",\"answer\":\"Among 632 patients, early clinical stability occurred in 48.9%, 88.9% of those patients were discharged after a median stay of 6 days, 3.2% required ICU transfer, and 10.9% died.\"}]","Characteristics and Outcomes of Cancer Patients Admitted to the Hospital With Community-Acquired Pneumonia | PDF",1790183971]