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This report describes a 57-year-old man with progressive myelopathy and radiculopathy caused by a gadolinium-enhancing cervical dumbbell tumor at C5/6. Two-stage microsurgical resection confirmed transitional and fibrous meningioma subtypes in intradural versus extraforaminal components, followed by cervical artificial disc replacement for delayed C5–6 spondylolisthesis. Complete neurological recovery was sustained with no recurrence at six years.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/cervical-dumbbell-meningioma-exhibiting-distinct-histopathological-subtypes-in-intradural-and-extradural-components-a-case-report/455782/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/cervical-dumbbell-meningioma-exhibiting-distinct-histopathological-subtypes-in-intradural-and-extradural-components-a-case-report/455782.png","ImageObject",300,407,{"name":92,"@type":93},"Jake","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",14,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What makes this case clinically unusual?","Question",{"text":113,"@type":114},"The cervical dumbbell meningioma shows distinct WHO grade I histopathological subtypes—transitional and fibrous—occurring in separate intradural and extradural/extraforaminal compartments within a single tumor.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How was the tumor treated surgically?",{"text":118,"@type":114},"The patient underwent a two-stage microsurgical excision: posterior laminotomy/laminoplasty for intradural tumor removal, followed by extraforaminal resection via a ventrolateral approach.",{"name":120,"@type":111,"acceptedAnswer":121},"What were the long-term outcomes after surgery?",{"text":122,"@type":114},"The patient achieved full neurological recovery and remained disease-free at a six-year follow-up. Delayed C5–6 spondylolisthesis developed later and was successfully managed with cervical artificial disc replacement.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},455782,1790793206,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":44,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},962084928904,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","Chen et al. BMC Neurology (2026) 26:14 [https://doi.org/10.1186/s12883-025-04550-5](https://doi.org/10.1186/s12883-025-04550-5)  \nBMC Neurology  \nCASE REPORT Open Access  \nCervical dumbbell meningioma exhibiting distinct histopathological subtypes in intradural and extradural components:  \na case report  \nChia-Yu Chen 1,2, Wei-Chuan Liao 1 and Chia-Ing Jan3,4*  \nAbstract  \nBackground Spinal dumbbell meningiomas are rare, accounting for only 4–5% of all spinal meningiomas. Histological heterogeneity within the same dumbbell lesion is even rarer, with all previously reported cases involving coexistence of a meningioma with either a schwannoma or a neurofibroma. To our knowledge, this is the first report of distinct meningioma subtypes occurring in separate anatomical compartments of a single dumbbell-shaped meningioma, a novel finding with important implications for surgical planning and outcomes.  \nCase presentation A 57-year-old man presented with progressive myelopathy and radiculopathy, including weakness and numbness of the left thumb and index finger, bilateral hyperreflexia, spasticity, and unsteady gait. Magnetic resonance imaging revealed a gadolinium-enhancing dumbbell-shaped tumour at the C5/6 level  \nwith a dural tail sign, consistent with an Eden type III spinal dumbbell tumour. The patient underwent two-stage microsurgical excision: initial posterior laminotomy and laminoplasty of C4–C6 with left C5/6 facetectomy for intradural tumour removal, followed by extraforaminal resection using a ventrolateral approach. Histopathology confirmed transitional and fibrous meningioma subtypes in the intradural and extraforaminal components, respectively. No fusion was performed after facetectomy, as postoperative alignment remained stable. Delayed C5–6 spondylol isthesis developed 2.5 years later and was successfully managed with cervical artificial disc replacement, restoring alignment and preserving motion. The patient achieved full neurological recovery with no recurrence at six-year follow-up.  \nConclusions Dumbbell cervical meningiomas can present with exceptional histopathological heterogeneity, with distinct transitional and fibrous subtypes identified in the intradural and extraforaminal components, respectively. The excellent long-term outcomes achieved with a tailored two-stage surgical approach highlight the importance of individual ised strategies for treating these rare and complex lesions. Recognising the potential histological diversity of dumbbell-shaped meningiomas is essential for effective surgical planning and optimisation of patient outcomes.  \n*Correspondence:  \nChia-Ing Jan [jc105105105@gmail.com](jc105105105@gmail.com)  \nFull list of author information is available at the end of the article  \n© The Author(s) 2025. Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit [http://creativecommons.org/l](http://creativecommons.org/l)icenses/by/4.0/.  \nHighlights  \n• This is the first reported case of a cervical dumbbell meningioma exhibiting two distinct WHO grade I subtypes—transitional and fibrous—located in separate anatomical compartments of a single tumour.  \n• A two-stage microsurgical strategy, combining a posterior approach followed by ventrolateral resection, achie","cbCailTgx05xMjaQ","https://ap.wps.com/l/cbCailTgx05xMjaQ","pdf",1681312,"English","# Abstract\n# Background\n# Case presentation\n# Conclusions\n# Highlights","[{\"question\":\"What makes this case clinically unusual?\",\"answer\":\"The cervical dumbbell meningioma shows distinct WHO grade I histopathological subtypes—transitional and fibrous—occurring in separate intradural and extradural/extraforaminal compartments within a single tumor.\"},{\"question\":\"How was the tumor treated surgically?\",\"answer\":\"The patient underwent a two-stage microsurgical excision: posterior laminotomy/laminoplasty for intradural tumor removal, followed by extraforaminal resection via a ventrolateral approach.\"},{\"question\":\"What were the long-term outcomes after surgery?\",\"answer\":\"The patient achieved full neurological recovery and remained disease-free at a six-year follow-up. Delayed C5–6 spondylolisthesis developed later and was successfully managed with cervical artificial disc replacement.\"}]","Cervical Dumbbell Meningioma Exhibiting Distinct Histopathological Subtypes in Intradural and Extradural Components - A Case Report | PDF",1790744320,23]