[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-152612-en":3,"doc-seo-152612-105":30,"detail-sidebar-cat-0-en-105":92},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":20,"is_deleted":4,"is_public":20,"is_downloadable":20,"audit_status":20,"page_count":21,"language":22,"language_code":23,"site_id":24,"html_lang":23,"table_of_contents":25,"faqs":26,"seo_title":27,"seo_description":14,"update_tm":28,"read_time":29},152612,1099513958607,"Jiven","https://ap-avatar.wpscdn.com/avatar/100002390cf8733938c?x-image-process=image/resize,m_fixed,w_180,h_180&k=1778829742770036399",7,"Healthcare","Cervical Artery Dissection - Review Article","Cervical artery dissection is a frequent cause of stroke in young adults. The review covers its pathophysiology, etiology, and risk factors, along with diagnostic evaluation, treatment strategies, and clinical outcomes. It emphasizes that the condition is multifactorial, with environmental triggers potentially acting in genetically predisposed patients. Neuroimaging confirmation is highlighted, as well as acute ischemic stroke evaluation for IV thrombolysis and endovascular eligibility. Antithrombotic therapy with anticoagulation or antiplatelet treatment is reviewed for secondary prevention.","REVIEW ARTICLE  \n􀀁  \nCONTINUUM AUDIO INTERVIEW AVAILABLE ONLINE  \nCITE AS:  \nCONTINUUM (MIN NEA P M INN) 2023;29(2, CEREBROVASCULAR DISEASE):540–565.  \nAddress correspondence to Dr Setareh Salehi Omran, 12401 East 17th Ave, MS L950, Aurora, CO 80045, setareh.  \n[salehiomran@cuanschutz.edu](salehiomran@cuanschutz.edu).  \nRELATIONSHIP DISCLOSURE: Dr Salehi Omran reports no disclosure.  \nUNLABELED USE OF PRODUCTS/INVESTIGATIONAL USE DISCLOSURE:  \nDr Salehi Omran reports no disclosure.  \n© 2023 American Academy of Neurology.  \nCervical Artery Dissection  \nBy Setareh Salehi Omran, MD  \nABSTRACT  \nOBJECTIVE: Cervical artery dissection is a common cause of stroke in young adults. This article reviews the pathophysiology, etiology and risk factors, evaluation, management, and outcomes of spontaneous cervical artery dissection.  \nLATEST DEVELOPMENTS: Cervical artery dissection is believed to be amultifactorial disease, with environmental factors serving as possible triggers in patients who have a genetic predisposition to dissection formation. Cervical artery dissection can cause local symptoms or ischemic events, such as ischemic stroke or transient ischemic attack. Neuroimaging is used to confirm the diagnosis; classic findings include along tapered arterial stenosis or occlusion, dissecting aneurysm, intimal flap, double lumen, or intramural hematoma. Patients with cervical artery dissection who present with an acute ischemic stroke should be evaluated for IV thrombolysis, endovascular therapy eligibility, or both. Antithrombotic therapy with either anticoagulation or antiplatelet treatment is used to prevent stroke from cervical artery dissection. The risk of recurrent ischemia appears low and is mostly limited to the first two weeks after symptom onset.  \nESSENTIAL POINTS: Cervical artery dissection is a known cause of ischemic strokes. Current data show no difference between the benefits and risks of anticoagulation versus antiplatelet therapy in the acute phase of symptomatic extracranial cervical artery dissection, thereby supporting the recommendation that clinicians can prescribe either treatment. Further research is warranted to better understand the pathophysiology and long-term outcomes of cervical artery dissection.  \nINTRODUCTION  \nD  \nissections are defined by blood collection and intramural hematoma formation in the arterial wall layers. Cervical artery dissection is a dissection in the carotid artery, vertebral artery, or both, and most commonly involves the extracranial portions of these arteries. Dissections can occur spontaneously or as a direct result of  \nsignificant trauma. About 15% to 24% of cases of ischemic stroke in young adults are due to cervical artery dissection, making it a common cause of stroke in this population.1,2  \n540 APRIL 2023  \nCopyright © American Academy of Neurology. Unauthorized reproduction of this article is prohibited.  \nThis article reviews the epidemiology, pathophysiology, risk factors, clinical presentations, evaluation, management, and outcomes of cervical artery dissection. In particular, recent insights on risk factors and treatment, including acute ischemic stroke management and secondary stroke prevention, are highlighted. Spontaneous cervical artery dissections are the main focus, as these are more commonly encountered by neurologists, whereas cervical artery dissection from major trauma is typically managed by surgeons. Purely intracranial dissections are not discussed and intracranial extension of extracranial cervical artery dissection is discussed briefly.  \nEPIDEMIOLOGY  \nThe overall incidence of cervical artery dissection is low in the general population, at an estimated 2.6 to 3.0 per 100,000 people per year.3,4 Internal carotid artery (ICA) dissections are more common than vertebral artery dissections (1.72 per 100,000 people per year; 95% confidence interval, 1.1 to 2.3 versus 0.97 per 100,000 people per year; 95% confidence interval, 0.5 to 1.4).3 The overall incide","cbCaiiub2u5VyfTw","https://ap.wps.com/l/cbCaiiub2u5VyfTw","pdf",2283608,1,26,"English","en",105,"# Abstract\n## Objective and scope\n## Latest developments and key points\n# Introduction\n## Definition and significance\n# Epidemiology\n## Incidence and demographics\n# Anatomy of Cervical Artery Dissection\n## Mechanisms and clinical manifestations","[{\"question\":\"What is cervical artery dissection and why is it clinically important?\",\"answer\":\"Cervical artery dissection involves blood collection and intramural hematoma formation in the arterial wall layers of the carotid and/or vertebral arteries. It is an established cause of ischemic stroke in young adults.\"},{\"question\":\"How is cervical artery dissection diagnosed?\",\"answer\":\"Neuroimaging is used to confirm the diagnosis. Classic findings include tapered arterial stenosis or occlusion, dissecting aneurysm, intimal flap, double lumen, and intramural hematoma.\"},{\"question\":\"What treatment is recommended for patients with acute ischemic stroke due to cervical artery dissection?\",\"answer\":\"Patients should be evaluated for IV thrombolysis and/or endovascular therapy eligibility. Antithrombotic therapy using either anticoagulation or antiplatelet treatment is used to prevent recurrent ischemic events, with low recurrence risk mostly limited to the first two weeks.\"}]","Cervical Artery Dissection - Review Article | PDF",1787864598,66,{"code":4,"msg":31,"data":32},"ok",{"site_id":24,"language":23,"slug":33,"title":13,"keywords":34,"description":14,"schema_data":35,"social_meta":87,"head_meta":89,"extra_data":91,"updated_unix":28},"cervical-artery-dissection-review-article","",{"@graph":36,"@context":86},[37,54,69],{"@type":38,"itemListElement":39},"BreadcrumbList",[40,44,48,51],{"item":41,"name":42,"@type":43,"position":20},"https://docshare.wps.com","Home","ListItem",{"item":45,"name":46,"@type":43,"position":47},"https://docshare.wps.com/document/","Document",2,{"item":49,"name":12,"@type":43,"position":50},"https://docshare.wps.com/document/healthcare/",3,{"item":52,"name":13,"@type":43,"position":53},"https://docshare.wps.com/document/cervical-artery-dissection-review-article/152612/",4,{"url":52,"name":13,"@type":55,"author":56,"headline":13,"publisher":58,"fileFormat":61,"inLanguage":23,"description":14,"dateModified":62,"datePublished":63,"encodingFormat":61,"isAccessibleForFree":64,"interactionStatistic":65},"DigitalDocument",{"name":9,"@type":57},"Person",{"url":41,"name":59,"@type":60},"DocShare","Organization","application/pdf","2026-09-04","2026-08-27",true,{"@type":66,"interactionType":67,"userInteractionCount":20},"InteractionCounter",{"@type":68},"ViewAction",{"@type":70,"mainEntity":71},"FAQPage",[72,78,82],{"name":73,"@type":74,"acceptedAnswer":75},"What is cervical artery dissection and why is it clinically important?","Question",{"text":76,"@type":77},"Cervical artery dissection involves blood collection and intramural hematoma formation in the arterial wall layers of the carotid and/or vertebral arteries. It is an established cause of ischemic stroke in young adults.","Answer",{"name":79,"@type":74,"acceptedAnswer":80},"How is cervical artery dissection diagnosed?",{"text":81,"@type":77},"Neuroimaging is used to confirm the diagnosis. Classic findings include tapered arterial stenosis or occlusion, dissecting aneurysm, intimal flap, double lumen, and intramural hematoma.",{"name":83,"@type":74,"acceptedAnswer":84},"What treatment is recommended for patients with acute ischemic stroke due to cervical artery dissection?",{"text":85,"@type":77},"Patients should be evaluated for IV thrombolysis and/or endovascular therapy eligibility. Antithrombotic therapy using either anticoagulation or antiplatelet treatment is used to prevent recurrent ischemic events, with low recurrence risk mostly limited to the first two weeks.","https://schema.org",{"og:url":52,"og:type":88,"og:title":13,"og:site_name":59,"og:description":14},"article",{"robots":90,"canonical":52},"index,follow",{"doc_id":7,"site_id":24},{"code":4,"msg":5,"data":93},[94,98,102,106,111,116,119,124,129,132,136],{"id":20,"doc_module":4,"doc_module_name":46,"category_name":95,"show_sort_weight":96,"slug":97},"Story & Novel",90,"story-novel",{"id":47,"doc_module":4,"doc_module_name":46,"category_name":99,"show_sort_weight":100,"slug":101},"Literature",80,"literature",{"id":53,"doc_module":4,"doc_module_name":46,"category_name":103,"show_sort_weight":104,"slug":105},"Exam",70,"exam",{"id":107,"doc_module":4,"doc_module_name":46,"category_name":108,"show_sort_weight":109,"slug":110},5,"Comic",60,"comic",{"id":112,"doc_module":4,"doc_module_name":46,"category_name":113,"show_sort_weight":114,"slug":115},6,"Technology",50,"technology",{"id":11,"doc_module":4,"doc_module_name":46,"category_name":12,"show_sort_weight":117,"slug":118},40,"healthcare",{"id":120,"doc_module":4,"doc_module_name":46,"category_name":121,"show_sort_weight":122,"slug":123},8,"Research & Report",30,"research-report",{"id":125,"doc_module":4,"doc_module_name":46,"category_name":126,"show_sort_weight":127,"slug":128},9,"Religion & Spirituality",20,"religion-spirituality",{"id":127,"doc_module":4,"doc_module_name":46,"category_name":130,"show_sort_weight":127,"slug":131},"World Cup","world-cup",{"id":133,"doc_module":4,"doc_module_name":46,"category_name":134,"show_sort_weight":133,"slug":135},10,"Lifestyle","lifestyle",{"id":137,"doc_module":4,"doc_module_name":46,"category_name":138,"show_sort_weight":107,"slug":139},19,"General","general"]