[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-336162-105":59,"doc-detail-336162-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","case-report-unusual-breast-cancer-metastasis-manifesting-as-a-scalp-lesion","Case report - Unusual breast cancer metastasis manifesting as a scalp lesion","","Case report documents a rare pattern of cutaneous metastasis in a breast cancer survivor. A scalp nodule discovered during routine surveillance was confirmed as distant metastatic breast cancer using nuclear imaging and histopathological examination. The patient previously had invasive lobular carcinoma treated six years earlier with surgery, adjuvant chemotherapy, endocrine therapy, and radiation, followed by long-term negative follow-up results. Findings emphasize vigilance for remote metastases presenting as skin lesions and the need for comprehensive monitoring in breast cancer survivors.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/case-report-unusual-breast-cancer-metastasis-manifesting-as-a-scalp-lesion/336162/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/case-report-unusual-breast-cancer-metastasis-manifesting-as-a-scalp-lesion/336162.png","ImageObject",300,407,{"name":92,"@type":93},"Ava Thompson","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-28","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",15,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Why is scalp cutaneous metastasis from breast cancer considered rare?","Question",{"text":113,"@type":114},"Cutaneous metastasis from breast cancer is uncommon, and scalp involvement far from the primary tumor site is especially infrequent. Invasive lobular carcinoma metastasizing to remote skin is also rare.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How was the scalp nodule evaluated in this case?",{"text":118,"@type":114},"The scalp nodule was confirmed as a distant metastatic lesion of breast origin through nuclear imaging and histopathological examination.",{"name":120,"@type":111,"acceptedAnswer":121},"What was the patient’s breast cancer history before the scalp lesion appeared?",{"text":122,"@type":114},"The patient had invasive lobular carcinoma of the left breast six years earlier and received surgery, adjuvant chemotherapy, tamoxifen, and radiation, with regular follow-ups showing no recurrence or distant metastasis until the scalp nodule visit.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},336162,1790044931,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":29,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":105},1649267921044,"https://us-avatar.wpscdn.com/avatar/1800007509477c92dfb?_k=1786009248482753345","TYPE Case Report  \nPUBLISHED 05 April 2024  \nDOI 10.3389/fonc.2024.1361333  \nOPEN ACCESS  \nEDITED BY  \nLidia Castagneto Gissey, Sapienza University of Rome, Italy  \nREVIEWED BY  \nIuliana Pantelimon,  \nCarol Davila University of Medicine and Pharmacy, Romania  \nTeodor Florin Georgescu,  \nCarol Davila University of Medicine and Pharmacy, Romania  \n*CORRESPONDENCE Ha Yeun Oh  \n [elefteria@hanmail.net](elefteria@hanmail.net)  \nRECEIVED 25 December 2023  \nACCEPTED 13 March 2024  \nPUBLISHED 05 April 2024  \nCITATION  \nKoh NH and Oh HY (2024) Case report: Unusual breast cancer metastasis manifesting as a scalp lesion in a patient with invasive lobular carcinoma.  \nFront. Oncol. 14:1361333 .  \ndoi: 10.3389/fonc.2024.1361333  \nCOPYRIGHT  \n© 2024 Koh and Oh. This is an open-access article distributed under the terms of the  \nCreative Commons Attribution License (CC BY) .  \nThe use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.  \nCase report: Unusual breast cancer metastasis manifesting asa scalp lesion in a patient with invasive lobular carcinoma  \nNam Hee Koh and Ha Yeun Oh*  \nDepartment of Radiology, Kangwon National University Hospital, Chuncheon, Republic of Korea  \nBreast cancer is the most prevalent cancer in women globally, often leading to distant metastasis in the lung, liver, or bones. Cutaneous metastasis represents an uncommon pattern in breast cancer, but when observed, it tends to manifest in the thorax and upper abdomen, primarily due to lymph node involvement. Therefore, occurrences of cutaneous metastasis on the scalp and extremities are infrequent. Moreover, invasive lobular carcinoma metastasizing to remote skin is rare among the breast cancer. This report presents a case of cutaneous metastasis of invasive lobular carcinoma to the scalp in a patient treated for breast cancer six years ago, with no signs of local recurrence or metastasis to other organs.  \nKEYWORDS  \ndistant metastasis, cutaneous metastasis, scalp metastasis, invasive lobular carcinoma of the breast, metastatic breast cancer, scalp nodule  \nIntroduction  \nBreast cancer is globally recognized as the most common cancer in women, with recent trends indicating an increase in both incidence and mortality rates worldwide (1) . With advancements in diagnostic technologies, developed countries have witnessed a decline in breast cancer mortality due to early detection and treatment. Paradoxically, however, statistical evidence suggests a rising incidence of metastatic breast cancer (2) .  \nMetastasis in breast cancer predominantly occurs in specific organs, with rare instances of cutaneous metastasis. Although cutaneous metastasis from breast cancer is uncommon, accounting for approximately 2.5%, it stands out as a relatively proficient entity compared to the less than 1% occurrence in general solid tumors. As a result, breast cancer demonstrates a heightened propensity for cutaneous metastasis, accounting for approximately 33% of all cases among metastatic cancers affecting the skin (3, 4) .  \nCutaneous metastasis primarily occurs in proximity to the primary tumor site, occasionally leading to misinterpretation as a secondary malignancy related to the recurrence or treatment of the primary lesion. Moreover, when tumors appear on the  \nFrontiers in Oncology 01 [frontiersin.org](frontiersin.org)  \nscalp or extremities far from the primary lesion, linking them to breast cancer becomes more challenging.  \nThis case report discusses a rare scenario where a scalp nodule, incidentally discovered during the surveillance period after breast cancer treatment, was confirmed and treated as a distant metastatic lesion of breast origin through nuclear imaging and histopathological examination. The fin","cbCaiuWxBKTkDhu4","https://ap.wps.com/l/cbCaiuWxBKTkDhu4","pdf",2717315,"English","# Introduction\n# Case presentation","[{\"question\":\"Why is scalp cutaneous metastasis from breast cancer considered rare?\",\"answer\":\"Cutaneous metastasis from breast cancer is uncommon, and scalp involvement far from the primary tumor site is especially infrequent. Invasive lobular carcinoma metastasizing to remote skin is also rare.\"},{\"question\":\"How was the scalp nodule evaluated in this case?\",\"answer\":\"The scalp nodule was confirmed as a distant metastatic lesion of breast origin through nuclear imaging and histopathological examination.\"},{\"question\":\"What was the patient’s breast cancer history before the scalp lesion appeared?\",\"answer\":\"The patient had invasive lobular carcinoma of the left breast six years earlier and received surgery, adjuvant chemotherapy, tamoxifen, and radiation, with regular follow-ups showing no recurrence or distant metastasis until the scalp nodule visit.\"}]","Case report - Unusual breast cancer metastasis manifesting as a scalp lesion | PDF",1790013935]