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A 66-year-old woman with a CRT-P underwent generator replacement and later transvenous lead extraction for pocket infection; intraoperative imaging showed lead and right atrial vegetations. Cultures unexpectedly identified Bacillus cereus. After standard empiric coverage, treatment used oritavancin in four fractionated weekly doses and added oral vancomycin to eradicate gastrointestinal carriage, with successful CRT-P reimplantation and no recurrence during 3 months of follow-up.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/cardiac-implantable-electronic-device-related-infective-endocarditis-caused-by-bacillus-cereus-a-case-report/461488/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/cardiac-implantable-electronic-device-related-infective-endocarditis-caused-by-bacillus-cereus-a-case-report/461488.png","ImageObject",300,407,{"name":92,"@type":93},"Blue Pony","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-06","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":81},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What organism caused the CIED-related infective endocarditis in this case?","Question",{"text":112,"@type":113},"Intraoperative cultures identified Bacillus cereus from surgical samples during the lead extraction procedure.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What diagnostic finding confirmed infection during transvenous lead extraction?",{"text":117,"@type":113},"Transoesophageal echocardiography revealed vegetations on the leads and in the right atrium.",{"name":119,"@type":110,"acceptedAnswer":120},"How was the infection treated, and what was the outcome?",{"text":121,"@type":113},"Oritavancin was given in four fractionated weekly doses, with oral vancomycin added to target gastrointestinal eradication. After four weeks of effective therapy, CRT-P was reimplanted, and no recurrence occurred during a 3-month follow-up.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},461488,1790793274,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":81,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145},962090760266,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","Case Report  \nCardiac Implantable Electronic Device-Related Infective Endocarditis Caused by Bacillus cereus: A Case Report  \nDenis Swolana 1, Danuta Łoboda 2,3, Beata Sarecka-Hujar 4, *, Rafał Sznajder 2, Anna Szajerska-Kurasiewicz 5, Tadeusz Z˛ebik 5, Krzysztof S. Gołba 2,3 and Robert D. Wojtyczka 1  \nAcademic Editors: Antonios  \nKaranasos and Teruhiko Imamura  \nReceived: 11 December 2025  \nRevised: 23 December 2025  \nAccepted: 30 December 2025  \nPublished: 2 January 2026  \nCopyright: © 2026 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.  \n1 Department of Microbiology, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, 4 Jagiello ´nska Str., 41-200 Sosnowiec, Poland; [dswolana@sum.edu.pl](dswolana@sum.edu.pl) (D.S.); [rwojtyczka@sum.edu.pl](rwojtyczka@sum.edu.pl) (R.D.W.)  \n2 Department of Electrocardiology, Upper-Silesian Medical Centre in Katowice, 45/47 Ziołowa Str., 40-635 Katowice, Poland; [dana.loboda@gmail.com](dana.loboda@gmail.com) (D.Ł.); [rafal.sznajder@gmail.com](rafal.sznajder@gmail.com) (R.S.); [kgolba@sum.edu.pl](kgolba@sum.edu.pl) (K.S.G.)  \n3 Department of Electrocardiology and Heart Failure, Faculty of Health Sciences in Katowice, Medical University of Silesia in Katowice, 45/47 Ziołowa Str., 40-635 Katowice, Poland  \n4 Department of Basic Biomedical Science, Faculty of Pharmaceutical Sciences in Sosnowiec, Medical University of Silesia in Katowice, 8b Jedno´sci Str., 41-200 Sosnowiec, Poland  \n5 Department of Cardiology, Municipal Hospital in Gliwice, 29 Kosciuszki Str., 44-100 Gliwice, Poland; [a.szajerska.kurasiewicz@gmail.com](a.szajerska.kurasiewicz@gmail.com) (A.S.-K.); [t.zebik@szpital4.gliwice.pl](t.zebik@szpital4.gliwice.pl) (T.Z.)  \n* [Correspondence: bsarecka-hujar@sum.edu.pl](Correspondence: bsarecka-hujar@sum.edu.pl); Tel.: +48-32-269-98-30  \nAbstract  \nBackground: Globalization, increased mobility, changes in dietary habits, and a growing number of immunocompromised patients have heightened exposure to rare or opportunistic pathogens. Here, we present a case of cardiac implantable electronic device-related infective endocarditis (CIED-IE) caused by Bacillus cereus bacteremia originating in the gastrointestinal tract. Case presentation: A 66-year-old female, who had a cardiac resynchronization pacemaker (CRT-P) implanted in 2017 due to second-degree atrioventricular block and left bundle branch block, had undergone device replacement due to battery depletion 4 months earlier and was scheduled for transvenous lead extraction (TLE) due to generator pocket infection. During the TLE procedure, transoesophageal echocardiography revealed vegetations on the leads and in the right atrium. Standard empirical therapy covering methicillin-resistant Staphylococci and Gram-negative bacteria was administered, including oritavancin and gentamicin. Surprisingly, intraoperative samples cultured B. cereus, a Gram-positive, spore-forming rod that usually causes food poisoning through contamination of rice and other starchy foods. B. cereus is generally resistant to β-lactam antibiotics except for carbapenems but is susceptible to glycopeptides. The oritavancin treatment was extended to four fractionated doses (1200, 800, 800, and 800 mg) administered at 7-day intervals. To eradicate bacteria in the gastrointestinal tract, oral vancomycin (125 mg 4 times a day) was added. After 4 weeks of effective antibiotic therapy, a CRT-P with a left bundle branch area pacing lead was reimplanted on the right subclavian area, with no recurrence of infection during the 3-month follow-up. Clinical discussion: In the patient, a diet high in rice and improper storage of rice dishes, together with habitual constipation, were identified as risk factors for the development of invasive Bacillus cereus infection. However, the long half-life lipoglycopeptide a","cbCaiba7d09KHrnt","https://ap.wps.com/l/cbCaiba7d09KHrnt","pdf",2309706,11,"English","# Abstract\n# Keywords\n# 1. Introduction\n# Case Presentation\n# Clinical Discussion\n# Conclusions","[{\"question\":\"What organism caused the CIED-related infective endocarditis in this case?\",\"answer\":\"Intraoperative cultures identified Bacillus cereus from surgical samples during the lead extraction procedure.\"},{\"question\":\"What diagnostic finding confirmed infection during transvenous lead extraction?\",\"answer\":\"Transoesophageal echocardiography revealed vegetations on the leads and in the right atrium.\"},{\"question\":\"How was the infection treated, and what was the outcome?\",\"answer\":\"Oritavancin was given in four fractionated weekly doses, with oral vancomycin added to target gastrointestinal eradication. After four weeks of effective therapy, CRT-P was reimplanted, and no recurrence occurred during a 3-month follow-up.\"}]","Cardiac Implantable Electronic Device-Related Infective Endocarditis Caused by Bacillus cereus - A Case Report | PDF",1790761711,28]