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This study quantified cancer incidence, mortality, and disability-adjusted life year (DALY) burden in China and compared the corresponding metrics with the United States and the United Kingdom. Using GLOBOCAN 2022 and Global Burden of Disease 2021 data, Joinpoint regression assessed temporal trends and calculated annual percent changes. Results reported 4,824,703 new cases, 2,574,176 deaths, and 71,037,170 DALYs in 2022, with shifting cancer patterns across sites and evolving risk burdens.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/cancer-situation-in-china-an-analysis-based-on-the-global-epidemiological-data-released-in-2024/332981/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/cancer-situation-in-china-an-analysis-based-on-the-global-epidemiological-data-released-in-2024/332981.png","ImageObject",300,407,{"name":92,"@type":93},"Valentina","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-11","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What data sources were used to analyze cancer in China, the US, and the UK?","Question",{"text":112,"@type":113},"The analysis used cancer incidence, mortality, and DALYs from the GLOBOCAN 2022 online database and the Global Burden of Disease 2021 study (GBD 2021).","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How were cancer trends assessed over time?",{"text":117,"@type":113},"Joinpoint regression models were used to analyze trends in cancer incidence and mortality across China, the US, and the UK, including annual percent changes (APCs) and optimal joinpoints.",{"name":119,"@type":110,"acceptedAnswer":120},"What were the main findings for 2022 in China?",{"text":121,"@type":113},"In 2022, China recorded about 4,824,703 new cancer cases and 2,574,176 cancer-related deaths, contributing to 71,037,170 DALYs, with incidence lower than the US and UK but mortality higher than the US.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},332981,1790073508,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":46,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":31,"preview_page_count":4},13056703020460,"https://ap-avatar.wpscdn.com/avatar/be000253dac470eee5d?_k=1778207105932848923","DOI: 10.1002/cac2.12627  \nORIGINAL ARTICLE  \nCancer situation in China: an analysis based on the global epidemiological data released in 2024  \nXiayao Diao1 ,†  Chao Guo1 ,†  Xin Du1  Zhenchong Chen2  Wenwu Liu2   Jianrong Guo2  \nYukai Jin2 ,†  Bowen Li1  Xuehan Gao1 Minju Jo2  Yi Zeng2  Chao Ding2   \n Shanqing Li1   Haibo Qiu2   \n1 Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing, P. R. China  \n2 Department of Gastric Surgery, State Key Laboratory of Oncology in South China, Guangdong Provincial Clinical Research Center for Cancer, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong, P. R. China  \nCorrespondence  \nHaibo Qiu, Department of Gastric Surgery, Sun Yat-sen University Cancer Center, Guangzhou 510060, Guangdong, P. R. China.  \n[Email:](Email: qiuhb@sysucc.org.cn)[ qiuhb@sysucc.org.cn](Email: qiuhb@sysucc.org.cn)  \nShanqing Li, Department of Thoracic Surgery, Peking Union Medical College Hospital, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100730, P. R. China.  \nEmail: [lishanqing@pumch.cn](lishanqing@pumch.cn)  \nFunding information  \nNational Postdoctoral Innovation Talent Support Program, Grant/Award Number: BX20240042; National High-Level Hospital Clinical Research Funding, Grant/Award Number:  \n2022-PUMCH-B-011; Natural Science Foundation of Guangdong Province, Grant/Award Number: 2022A1515012347; Beijing CSCO research fund,  \nGrant/Award Number: Y-2019Roche-157  \nAbstract  \nBackground: Cancer remains a major cause of mortality and a significant economic burden in China. Exploring the disparities in cancer patterns and control strategies between China and developed countries may offer valuable insights for policy formulation and enhance cancer management efforts. This study examined the incidence, mortality, and disability-adjusted life year (DALY) burden of cancer in China, and compared these metrics with those observed in the United States (US) and the United Kingdom (UK) .  \nMethods: Data on cancer incidence, mortality, and DALYs for China, the US, and the UK were sourced from the GLOBOCAN 2022 online database and the Global Burden of Disease 2021 study (GBD 2021) . We utilized Joinpoint regression models to analyze trends in cancer incidence and mortality across these countries, calculating annual percent changes (APCs) and determining the optimal joinpoints.  \nResults: In 2022, China recorded around 4,824,703 new cancer cases and 2,574,176 cancer-related deaths, contributing to 71,037,170 DALYs. China exhibited a lower cancer incidence rate compared to the US and the UK. Although cancer-related mortality in China is slightly lower than that in the UK, it is significantly higher than that in the US. Additionally, China experienced significantly  \nList of abbreviations: AAPC, average annual percent change; APC, annual percent change; ASIR, age-standardized incidence rate; ASMR,  \nage-standardized mortality rate; CI, confidence interval; DALY, disability-adjusted life year; EBV, Epstein-Barr virus; GBD, Global Burden of Disease; GHDx, Global Health Data Exchange; H. pylori, Helicobacter pylori; HBV, hepatitis B virus; HPV, human papillomavirus; IARC, International Agency for Research on Cancer; IHME, Institute for Health Metrics and Evaluation; UK, United Kingdom; US, United States; WHO, World Health Organization.  \n†Xiayao Diao, Chao Guo, and Yukai Jin contributed equally to this work.  \nThis is an open access article under the terms of the Creative Commons Attribution-NonCommercial-NoDerivs License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non-commercial and no modifications or adaptations are made.  \n© 2024 The Author(s) . Cancer Communications published by John Wiley & Sons Australia, Ltd on behalf of Sun Yat-sen University Cancer Center.  \nDIAO et al.  \nhigher DALY rates compared to both the US and UK. ","cbCaic2o1eFnsm6Y","https://ap.wps.com/l/cbCaic2o1eFnsm6Y","pdf",2431747,"English","# Background\n## Methods\n## Results\n## Conclusions\n## List of abbreviations","[{\"question\":\"What data sources were used to analyze cancer in China, the US, and the UK?\",\"answer\":\"The analysis used cancer incidence, mortality, and DALYs from the GLOBOCAN 2022 online database and the Global Burden of Disease 2021 study (GBD 2021).\"},{\"question\":\"How were cancer trends assessed over time?\",\"answer\":\"Joinpoint regression models were used to analyze trends in cancer incidence and mortality across China, the US, and the UK, including annual percent changes (APCs) and optimal joinpoints.\"},{\"question\":\"What were the main findings for 2022 in China?\",\"answer\":\"In 2022, China recorded about 4,824,703 new cancer cases and 2,574,176 cancer-related deaths, contributing to 71,037,170 DALYs, with incidence lower than the US and UK but mortality higher than the US.\"}]","Cancer situation in China - an analysis based on the global epidemiological data released in 2024 | PDF",1790000271]