[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-379197-105":59,"doc-detail-379197-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","cancer-incidence-in-living-liver-donors-after-donor-hepatectomy","Cancer Incidence in Living Liver Donors After Donor Hepatectomy","","Living liver donors (LLDs) undergo screening for transmissible diseases, yet cancer risk after donation has not been well established. Using Korean National Health Insurance Services data, the study compared 12,372 LLDs registered in the Korean Network for Organ Sharing (2002–2018) with a matched healthy control group from the general population. Cancer was diagnosed in 1.4% of LLDs versus 0.8% of controls, with higher incidence rate ratios for liver and thyroid cancer. Incidences of 11 other specified cancers were similar.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/cancer-incidence-in-living-liver-donors-after-donor-hepatectomy/379197/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/cancer-incidence-in-living-liver-donors-after-donor-hepatectomy/379197.png","ImageObject",300,407,{"name":92,"@type":93},"Aditya","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-25","2026-09-24",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"How was cancer incidence in living liver donors evaluated in this study?","Question",{"text":112,"@type":113},"The study used Korean NHIS data and compared 12,372 living liver donors (donations from 2002 to 2018) with a matched healthy control group from the general Korean population.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What were the overall cancer diagnosis rates for donors versus controls?",{"text":117,"@type":113},"Cancer was diagnosed in 175 living liver donors (1.4%) and 1,014 controls (0.8%).",{"name":119,"@type":110,"acceptedAnswer":120},"Which cancer types showed significantly higher incidence in donors compared with controls?",{"text":121,"@type":113},"The incidence rate ratios were significantly higher for liver cancer (18.30) and thyroid cancer (1.39) in the living liver donor group.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},379197,1790431739,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":39,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144},962085564549,"https://ap-avatar.wpscdn.com/davatar_085a072bc5b1113ac321206ff7593b45","J Korean Med Sci. 2023 Sep 4;38(35):e277 [https://doi.org/10.3346/jkms.2023.38.e277](https://doi.org/10.3346/jkms.2023.38.e277)[ ](https://doi.org/10.3346/jkms.2023.38.e277)eISSN 1598-6357·pISSN 1011-8934  \nBrief Communication  \nOncology & Hematology  \nReceived: Feb 27, 2023  \nAccepted: Jun 26, 2023  \nPublished online: Aug 17, 2023  \nAddress for Correspondence:  \nJongman Kim, MD, PhD  \nDepartment of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, 81 Irwon-ro, Gangnam-gu, Seoul 06351, Korea. [Email: yjongman21@gmail.com](Email: yjongman21@gmail.com)  \n© 2023 The Korean Academy of Medical Sciences.  \nThis is an Open Access article distributed under the terms of the Creative Commons Attribution Non-Commercial License ([https://](https://)[ ](https://)[creativecommons.org/licenses/by-nc/4.0/](creativecommons.org/licenses/by-nc/4.0/)) which permits unrestricted non-commercial use, distribution, and reproduction in any medium, provided the original work is properly cited.  \nORCID iDs  \nJongman Kim  [https://orcid.org/0000-0002-1903-8354](https://orcid.org/0000-0002-1903-8354)[ ](https://orcid.org/0000-0002-1903-8354)Jae Heon Kim  [https://orcid.org/0000-0002-4490-3610](https://orcid.org/0000-0002-4490-3610)[ ](https://orcid.org/0000-0002-4490-3610)Hyun Jung Kim  [https://orcid.org/0000-0003-2018-2385](https://orcid.org/0000-0003-2018-2385)  \nFunding  \nThe present study was funded or supported by the Korean Network for Organ Sharing of the Ministry of Health and Welfare (NHIS- 2020-1-041) . The Korean NHIS helped with data collection in this study but had no influence on study design, data analysis, data interpretation, or drafting of the manuscript.  \nCancer Incidence in Living Liver Donors After Donor Hepatectomy  \nJongman Kim ,1 Jae Heon Kim ,2 and Hyun Jung Kim  3  \n1Department of Surgery, Samsung Medical Center, Sungkyunkwan University School of Medicine, Seoul, Korea  \n2Department of Urology, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Korea  \n3Department of Preventive Medicine, Korea University, Seoul, Korea  \nABSTRACT  \nLiving liver donors (LLDs) are screened for transmissible diseases including cancer. We investigated the actual cancer incidence of LLDs compared with a matched healthy control group from the general Korean population using data from the Korean National Health Insurance Services (NHIS). A total of 12,372 LLDs who donated a liver graft between 2002 and 2018 were registered in the Korean Network for Organ Sharing. They were compared to a matched healthy control group selected from the Korean NHIS. Cancer diagnosis was identified in 175 LLDs (1.4%) and 1,014 controls (0.8%). Compared to the healthy control group, the incidence rate ratio of liver and thyroid cancer in the LLD group were significantly higher at 18.30 and 1.39, respectively. The incidences of 11 other specified cancers were not different between the two groups. The present study suggests that LLD after donor hepatectomy may require medical surveillance, especially for liver cancer.  \nKeywords: Living Liver Donors; Liver Transplantation; Malignancy  \nLiving liver donors (LLDs) are carefully evaluated for transmissible diseases and other chronic medical morbidities that might influence the donor’s health and the viability of the donated liver graft.1-3 Thus, short-term outcomes following a donation in LLDs are generally excellent.3 Recently we reported that the mortality of LLDs is higher than in highly selected healthy control groups.2 LLDs are thoroughly evaluated before donation and are generally young and healthy, thus one may expect that cancer risk will not increase after donation, but this has not been studied at all. Our previous study showed that the incidence of malignancy in LLDs was significantly higher than in the healthy control group (incidence rate ratio [IRR] for malignancy among LLDs = 1.74 [range, 1.47–2.06]) .2  \nWe investigated whether there was a difference","cbCaiiTg0rSPNkee","https://ap.wps.com/l/cbCaiiTg0rSPNkee","pdf",962790,"English","# Abstract\n# Background and Rationale\n# Study Population and Data Sources\n# Cancer Incidence and Site-Specific Results\n# Definitions and Cancer Classification\n# Outcomes and Data Statements","[{\"question\":\"How was cancer incidence in living liver donors evaluated in this study?\",\"answer\":\"The study used Korean NHIS data and compared 12,372 living liver donors (donations from 2002 to 2018) with a matched healthy control group from the general Korean population.\"},{\"question\":\"What were the overall cancer diagnosis rates for donors versus controls?\",\"answer\":\"Cancer was diagnosed in 175 living liver donors (1.4%) and 1,014 controls (0.8%).\"},{\"question\":\"Which cancer types showed significantly higher incidence in donors compared with controls?\",\"answer\":\"The incidence rate ratios were significantly higher for liver cancer (18.30) and thyroid cancer (1.39) in the living liver donor group.\"}]","Cancer Incidence in Living Liver Donors After Donor Hepatectomy | PDF",1790234566,13]