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Data were drawn from GLOBOCAN 2022, C15 plus cancer incidence series, and GBD 2021, assessing incidence, mortality, DALYs, and risk factors using join-point regression and linear regression. Results show higher incidence, mortality, and DALYs in China, with notable diet-related risks and smoking-linked lung DALYs, and an emerging rise in breast and thyroid cancers.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/research-report/","Research & Report",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/cancer-burden-and-attributable-risk-factors-of-cancers-in-china-epidemiological-insights-and-comparisons-with-india/328824/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/cancer-burden-and-attributable-risk-factors-of-cancers-in-china-epidemiological-insights-and-comparisons-with-india/328824.png","ImageObject",300,407,{"name":42,"@type":43},"Levi","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-10-28","2026-09-21",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",7,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"What was the study’s main objective regarding cancer in China and India?","Question",{"text":63,"@type":64},"To comprehensively analyze cancer burden, time trends, and attributable risk factors in China and compare these patterns with India.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"Which data sources and statistical approaches were used?",{"text":68,"@type":64},"The study used GLOBOCAN 2022, the C15 plus series, and GBD 2021, with join-point regression for time trends and linear regression to relate DALY rates with risk factors.",{"name":70,"@type":61,"acceptedAnswer":71},"What were the key findings about China versus India?",{"text":72,"@type":64},"China showed higher incidence, mortality, and DALY rates for multiple cancers. 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Understanding the epidemiology of cancer can guide the development of effective prevention and control strategies. This study aimed to comprehensively analyze the cancer burden, time trends, and attributable risk factors of cancers in China and compare them with those in India.  \nMethods: We utilized the GLOBOCAN database for 2022, Cancer Incidence in Five Continents (C15 plus) series, and Global Burden of Disease (GBD) 2021 to extract data on cancer incidence, mortality, disability-adjusted life years (DALYs), and risk factors. Time-trend analysis was performed using a join-point regression model. Correlations between cancer DALY rates and risk factors were analyzed using linear regression.  \nResults: In 2022, China experienced 4,824,703 new cancer cases and 2,574,176 cancer-related deaths. Cancers also caused approximately 71.2 million DALYs in China in 2021. Compared with India, China has higher incidence, mortality, and DALY rates for various cancers. Breast and thyroid cancers in China have shown a rapid increase in the age-standardized incidence rate (ASIR), along with a substantial burden of lung, stomach, esophageal, and colorectal cancer. However, stomach and liver cancersin China showed a downward trend in ASIR. In 2021, diet low in milk was a major risk factor among females for colorectal cancer DALYs in China (23% of age-standardized DALYs) and India (22.9%). In China, smoking has been associated with increased DALYs due to lung cancer.  \nConclusions: China has a heavier cancer burden than India. The heavy burden of lung, stomach, esophageal, and colorectal cancers, combined with the rising incidence of breast and thyroid cancers, pose a critical challenge to public health in China. Cancer burden may be reduced through public health initiatives that prioritize primary prevention, prompt identification, and therapeutic intervention.  \nKeywords  \nincidence, mortality, neoplasms, epidemiology, risk factors  \nReceived May 17, 2024. Received revised July 2, 2024. Accepted for publication August 2, 2024.  \nIntroduction  \nCancer is a major public health issue worldwide. During the current century, cancer is likely to be the principal cause of premature mortality globally and the most significant barrier to further advancements in life expectancy.1 The incidence and mortality rates of cancer vary among countries due to various factors, including socioeconomic status, health care  \n1 Cancer Institute, The Fourth Hospital of Hebei Medical University and Hebei Tumor Hospital, Shijiazhuang, China  \nCorresponding Author:  \nYutong He, Cancer Institute, The Fourth Hospital of Hebei Medical University and Hebei Tumor Hospital, Shijiazhuang 050011, China.  \nEmail: [heyutong@hebmu.edu.cn](heyutong@hebmu.edu.cn)  \nData Availability Statement included at the end of the article  \nCreative Commons Non Commercial CC BY-NC: This article is distributed under the terms of the Creative Commons  \nAttribution-NonCommercial 4.0 License ([https://creativecommons.org/licenses/by-nc/4.0/](https://creativecommons.org/licenses/by-nc/4.0/)) which permits non-commercial use,  \nreproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages ([https://us.sagepub.com/en-us/nam/open-access-at-sage](https://us.sagepub.com/en-us/nam/open-access-at-sage)).  \naccessibility, and lifestyle choices. High-income countries have high rates of c","cbCais8sikifUZ0U","https://ap.wps.com/l/cbCais8sikifUZ0U","pdf",3722054,18,"English","# Abstract\n## Background\n## Methods\n## Results\n## Conclusions\n# Introduction\n## Global and country-level cancer burden\n## China–India comparisons and key trends","[{\"question\":\"What was the study’s main objective regarding cancer in China and India?\",\"answer\":\"To comprehensively analyze cancer burden, time trends, and attributable risk factors in China and compare these patterns with India.\"},{\"question\":\"Which data sources and statistical approaches were used?\",\"answer\":\"The study used GLOBOCAN 2022, the C15 plus series, and GBD 2021, with join-point regression for time trends and linear regression to relate DALY rates with risk factors.\"},{\"question\":\"What were the key findings about China versus India?\",\"answer\":\"China showed higher incidence, mortality, and DALY rates for multiple cancers. The study also reported rapid increases in breast and thyroid cancers in China and identified major risk factors such as diet low in milk for colorectal cancer DALYs among females.\"}]","Cancer Burden and Attributable Risk Factors of Cancers in China - Epidemiological Insights and Comparisons With India | PDF",1789981221,45]