[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-331249-105":59,"doc-detail-331249-en":134},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":127,"head_meta":129,"extra_data":131,"updated_unix":133},105,"en","burden-of-major-cancer-types-in-almaty-kazakhstan","Burden of major cancer types in Almaty, Kazakhstan","","Burden of major cancer types in Almaty, Kazakhstan (2017–2021) evaluates common cancers using Ministry of Health information system data. The study estimates DALYs from disability (YLD) and premature death (YLL), finding 25,016.60 total DALYs in 2021, with mortality dominating disability (95.2% vs. 4.7%). Non-fatal burden (YLD) share increased for most selected cancers, except stomach and cervical. Patterns show overall growth alongside declines in specific cancers, supporting cancer control effectiveness. Results emphasize continuous, comprehensive strategies, including HPV vaccination, stomach screening, and awareness initiatives.",{"@graph":69,"@context":126},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/burden-of-major-cancer-types-in-almaty-kazakhstan/331249/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/burden-of-major-cancer-types-in-almaty-kazakhstan/331249.png","ImageObject",300,407,{"name":92,"@type":93},"Theodore","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-22","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":29},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118,122],{"name":109,"@type":110,"acceptedAnswer":111},"What cancers and time period does the study cover in Almaty?","Question",{"text":112,"@type":113},"The analysis evaluates the burden of common cancers in Almaty, Kazakhstan, over 2017 to 2021 using Ministry of Health data.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How are DALYs used to assess cancer burden?",{"text":117,"@type":113},"DALYs combine years of life lost due to premature mortality (YLL) and years lived with disability (YLD), using disability weights to quantify severity.",{"name":119,"@type":110,"acceptedAnswer":120},"What is the 2021 DALY burden and how much is due to mortality versus disability?",{"text":121,"@type":113},"In 2021, selected cancer types accounted for a total DALY burden of 25,016.60, with mortality contributing more than disability (95.2% vs. 4.7%).",{"name":123,"@type":110,"acceptedAnswer":124},"Which factors does the study suggest to support continuous cancer control?",{"text":125,"@type":113},"The results highlight the need for ongoing strategies including HPV vaccination, stomach cancer screening programs, and initiatives to increase cancer awareness.","https://schema.org",{"og:url":83,"og:type":128,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":130,"canonical":83},"index,follow",{"doc_id":132,"site_id":62},331249,1790174753,{"code":4,"msg":5,"data":135},{"doc_id":132,"user_id":136,"nickname":92,"user_avatar":137,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":138,"file_id":139,"file_url":140,"file_type":141,"file_size":142,"view_count":29,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":143,"language":144,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":145,"faqs":146,"seo_title":147,"seo_description":67,"update_tm":148,"read_time":149},7971461740886,"https://ap-avatar.wpscdn.com/davatar_3d24733baf745e90a7e4bdd5f77d97b2","[www. nature.com/scientificreports](www. nature.com/scientificreports)  \nOPEN  \nBurden of major cancer types in Almaty, Kazakhstan  \nFatima Kassymbekova1, Natalya Glushkova2*, Gauhar Dunenova2, Dilyara Kaidarova3, Katarzyna Kissimova‑Skarbek4, AnneleneWengler8, Indira Zhetpisbayeva5,  \nOxana Shatkovskaya3, Olga Andreyeva7, Kairat Davletov 5, ArdakAuyezova6 & Alexander Rommel8  \nGlobally, cancer is the second leading cause of death, with a growing burden also observed in Kazakhstan. This study evaluates the burden of common cancers in Almaty, Kazakhstan’s major city, from 2017 to 2021, utilizing data from the Information System of the Ministry of Health. In Kazakhstan, most common cancers among men include lung, stomach, and prostate cancer, while breast, cervical, and colorectal cancers are predominant among women. Employing measures like disability‑adjusted life years (DALYs), we found that selected cancer types accounted for a total DALY burden of 25,016.60 in 2021, with mortality contributing more than disability (95.2% vs. 4.7%) with the ratio of non‑fatal to fatal outcomes being 1.4 times higher in women than in men. The share of non‑fatal burden (YLD) proportion within DALYs increased for almost all selected cancer types, except stomach and cervical cancer over the observed period in Almaty. Despite the overall increase in cancer burden observed during the time period, a downward trend in specific cancers suggests the efficacy of implemented cancer control strategies. Comparison with global trends highlights the significance of targeted interventions. This analysis underscores the need for continuous comprehensive cancer control strategies in Almaty and Kazakhstan, including vaccination against human papillomavirus, stomach cancer screening programs, and increased cancer awareness initiatives.  \nKeywords Burden of disease, Disability-adjusted life years, Neoplasms, Almaty, Kazakhstan  \nThe disability-adjusted life year (DALY) was introduced by the World Bank in 1993 to assess the worldwide burden of disease and help in prioritizing the development of health policies1. The DALY is a quantitative measure that combines both death (measured in years of life lost owing to premature mortality [YLL]) and disability (measured in years lived with disability [YLD]) over a specific period of time. Thus, the main aim of the burden of disease concept is to make disease and death comparable on a unified scale, which is the YLL, allowing for ranking of the impacts of different diseases on population health. To this end, adjustments are made when calculating YLD using disability weights (DW) to weight disease in populations according to level of severity. Cancer has become the second most common cause of death worldwide2, estimated at over 18.1 million new cases (without non-melanoma skin cancer) and nearly 10.0 million cancer-related deaths in 20203. This makes cancer the main obstacle to increasing life expectancy in all countries worldwide4. The burden of malignant diseases continues to increase globally. A 47% rise in cancer incidence is projected on a global scale by 2040, with most of this increase in transitioning countries owing to population growth and aging3. The most prevalent types of malignant neoplasm are breast, lung, colorectal, prostate, stomach, and cervical cancers5. Kazakhstan belongs to the countries with a high-middle Socio-Demographic index (SDI) (0.723 in 2019) and is in the early stages of demographic aging with an increasing proportion of older people in the age structure of the country’s population (7.1% in 2009 and 8.3% in 2023) and city residents (56.1% in 2009 and up to 61.2% in 2023)6,7. Kazakhstan is a country with a relatively young population with high under age 25 fertility rate of 0.867 (over 60% higher than in average in high-middle SDI group of countries, which in year 2019 was 0.537)8. At the same time, the socio-economic and cultural landscape of Kazakhstan is characterized by significant differen","cbCaivjF3ERsjboS","https://ap.wps.com/l/cbCaivjF3ERsjboS","pdf",1437172,14,"English","# Study overview\n## Cancer burden measurement (DALYs)\n## Findings across cancer types (2017–2021)\n## Implications for cancer control strategies","[{\"question\":\"What cancers and time period does the study cover in Almaty?\",\"answer\":\"The analysis evaluates the burden of common cancers in Almaty, Kazakhstan, over 2017 to 2021 using Ministry of Health data.\"},{\"question\":\"How are DALYs used to assess cancer burden?\",\"answer\":\"DALYs combine years of life lost due to premature mortality (YLL) and years lived with disability (YLD), using disability weights to quantify severity.\"},{\"question\":\"What is the 2021 DALY burden and how much is due to mortality versus disability?\",\"answer\":\"In 2021, selected cancer types accounted for a total DALY burden of 25,016.60, with mortality contributing more than disability (95.2% vs. 4.7%).\"},{\"question\":\"Which factors does the study suggest to support continuous cancer control?\",\"answer\":\"The results highlight the need for ongoing strategies including HPV vaccination, stomach cancer screening programs, and initiatives to increase cancer awareness.\"}]","Burden of major cancer types in Almaty, Kazakhstan | PDF",1789992405,35]