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This study evaluates the gastrointestinal cancer burden in 2019, quantifies temporal trends from 1990–2019, and projects future patterns through 2044. Incidence, deaths, and DALYs were derived from the 2019 Global Burden of Disease, injuries, and Risk Factors study, including estimated annual percentage changes.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/burden-of-gastrointestinal-cancers-among-adolescent-and-young-adults-in-asia-pacific-region-trends-from-1990-to-2019-and-future-predictions-to-2044/331529/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/burden-of-gastrointestinal-cancers-among-adolescent-and-young-adults-in-asia-pacific-region-trends-from-1990-to-2019-and-future-predictions-to-2044/331529.png","ImageObject",300,407,{"name":92,"@type":93},"Quinn","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-04","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is the main goal of the study on gastrointestinal cancer burden?","Question",{"text":112,"@type":113},"To assess the gastrointestinal cancer burden among adolescents and young adults in the Asia-Pacific region in 2019, while analyzing trends from 1990 to 2019 and projecting future patterns to 2044.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How were incidence, deaths, and DALYs estimated in this research?",{"text":117,"@type":113},"Annual case numbers and age-standardized rates for incidence, death, and DALYs were derived from the Global Burden of Disease, injuries, and Risk Factors study 2019, with estimated annual percentage changes computed for trends.",{"name":119,"@type":110,"acceptedAnswer":120},"What were the key findings for 2019 in the Asia-Pacific region?",{"text":121,"@type":113},"In 2019 there were 117,714 incident cases, 61,578 deaths, and 3,483,053 DALYs due to gastrointestinal cancers, representing large shares of global burden in this population.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},331529,1790082935,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},962075114765,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","AnnAls of Medicine  \n2024, Vol. 56, no. 1, 2427367  \n[https://doi.org/10.1080/07853890.2024.2427367](https://doi.org/10.1080/07853890.2024.2427367)  \nReseaRch aRticle    \nBurden of gastrointestinal cancers among adolescent and young adults in Asia-Pacific region: trends from 1990 to 2019 and future predictions to 2044  \nDecai Zhanga,b, shaojun liua,b, Zhaoqi lia,b, Minxue shenc, Zihao lid,e and Rui Wanga,b   \nadepartment of Gastroenterology, The Third Xiangya Hospital of central south University, changsha, Hunan Province, china; bHunan Key laboratory of nonresolving inflammation and cancer, changsha, Hunan Province, china; cdepartment of social Medicine and Health Management, Xiangya school of Public Health, central south University, changsha, china; ddepartment of epidemiology and Health statistics, Xiangya school of Public Health, central south University, changsha, china; eThe first People’s Hospital of changde city, changde city, Hunan Province, china  \nABSTRACT  \nBackground: Gastrointestinal cancer is a significant cause of cancer incidence and mortality. Nevertheless, the epidemiology of the burden among adolescents and young adults (aYas, aged 15–39 years) remains limited in the asia-Pacific region, despite the region’s significant population. this study aims to explore the gastrointestinal cancer burden among aYas in the asia-Pacific region for the year 2019, while also analysing trends from 1990 to 2019 and projecting future trends up to 2044.  \nMethods: annual case numbers, age-standardized rates of incidence, death, and disability-adjusted life-years (DalYs) and their estimated annual percentage changes (eaPcs) for gastrointestinal cancers were derived from the Global Burden of Disease, injuries, and Risk Factors study 2019. trends over the next 25 years have also been predicted.  \nResults: in 2019, there were 117,714 incident cases, 61,578 deaths and 3,483,053 DalYs due to gastrointestinal cancers in the asia-Pacific region, accounting for 68.5%, 67.6% and 72.4%, respectively, of global gastrointestinal cancers in this population. the highest agestandardized rates occurred in countries with a middle socio-demographic index. From 1990 to 2019, there was a decline in the age-standardized rates of incidence, death and DalY attributed to gastrointestinal cancers, with eaPc of −1.10, −2.48 and −2.44, respectively. these rates are expected to stabilize over 25 years, with notable variations in individual gastrointestinal cancers. Conclusions: Gastrointestinal cancers among aYas in the asia-Pacific region have posed a significant burden over the past 30 years and are expected to persist in the coming years.  \nAbbreviations: Gi: cancers, gastrointestinal cancers; aYas: adolescents and young adults; GBD: Global Burden of Disease, injuries, and Risk Factors study; asR: age-standardized rate; ci: confidence interval; DalY: Disability-adjusted life-year; eaPc: estimated annual percentage change; sDi: sociodemographic index; Ui: Uncertainty interval; YlD: Years lived with disability.  \nARTICLE HISTORY  \nReceived 21 august 2023 Revised 13 October 2024 accepted 21 October 2024  \nKEYWORDS  \nGastrointestinal cancers; adolescent and young adults; asia-Pacific region; global burden of disease; disability-adjusted life years; prediction  \nIntroduction  \nindividuals aged 15–39 years were defined as adolescents and young adults (aYas) [1,2] . the incidence of cancer among aYas is a significant concern because it can have far-reaching social consequences, primarily stemming from the potential for prolonged organ dysfunction, diminished fertility and premature mortality [3] . the distinctive cancer biology of aYas results in a  \nrelatively poor treatment response compared to younger and older groups [4] . Unfortunately, this population is usually grouped with adult patients in clinical studies and the assessment of epidemiological patterns is inadequate [1] .  \nGastrointestinal (Gi) cancers are one of the most common cancers worldwide, ac","cbCaisSCLbg4ADzW","https://ap.wps.com/l/cbCaisSCLbg4ADzW","pdf",2013753,14,"English","# Abstract\n## Background\n## Methods\n## Results\n## Conclusions\n## Abbreviations\n# Introduction","[{\"question\":\"What is the main goal of the study on gastrointestinal cancer burden?\",\"answer\":\"To assess the gastrointestinal cancer burden among adolescents and young adults in the Asia-Pacific region in 2019, while analyzing trends from 1990 to 2019 and projecting future patterns to 2044.\"},{\"question\":\"How were incidence, deaths, and DALYs estimated in this research?\",\"answer\":\"Annual case numbers and age-standardized rates for incidence, death, and DALYs were derived from the Global Burden of Disease, injuries, and Risk Factors study 2019, with estimated annual percentage changes computed for trends.\"},{\"question\":\"What were the key findings for 2019 in the Asia-Pacific region?\",\"answer\":\"In 2019 there were 117,714 incident cases, 61,578 deaths, and 3,483,053 DALYs due to gastrointestinal cancers, representing large shares of global burden in this population.\"}]","Burden of gastrointestinal cancers among adolescent and young adults in Asia-Pacific region: trends from 1990 to 2019 and future predictions to 2044 | PDF",1789993755,35]