[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-356482-105":59,"doc-detail-356482-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","breast-cancer-metastasis-with-a-ureteral-obstruction-and-bladder-mass","Breast Cancer Metastasis with a Ureteral Obstruction and Bladder Mass","","Breast cancer is a leading cause of cancer mortality among women and a substantial fraction of patients develop metastatic disease. This open-access case report describes breast cancer metastasis presenting with ureteral obstruction and a bladder mass in a 60-year-old African-American female. After a decade of surveillance following bilateral radical mastectomy for invasive ductal carcinoma, incidental imaging revealed hydronephrosis. Cystoscopy identified a bladder mass obstructing the right ureteral orifice, and pathology supported metastatic breast cancer, highlighting rare solitary involvement and the clinical value of imaging and immunohistochemical confirmation.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/breast-cancer-metastasis-with-a-ureteral-obstruction-and-bladder-mass/356482/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/breast-cancer-metastasis-with-a-ureteral-obstruction-and-bladder-mass/356482.png","ImageObject",300,407,{"name":92,"@type":93},"Aurelia","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-29","2026-09-23",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",13,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What makes this case of breast cancer metastasis unusual?","Question",{"text":113,"@type":114},"The patient remained asymptomatic for over a decade, and the bladder was the solitary metastatic site associated with ureteral obstruction. Bladder metastases are also uncommon, and many reported cases involve invasive lobular carcinoma rather than invasive ductal carcinoma.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How was the bladder mass and ureteral obstruction diagnosed?",{"text":118,"@type":114},"Incidental imaging revealed right hydronephrosis. Subsequent cystoscopy showed a bladder mass obstructing the right ureteral orifice, and transurethral resection plus ureteral stent placement were performed.",{"name":120,"@type":111,"acceptedAnswer":121},"How did clinicians determine the bladder lesion was metastatic breast cancer?",{"text":122,"@type":114},"Pathology findings favored metastatic breast cancer, supported by immunohistochemical markers consistent with the primary invasive ductal carcinoma.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},356482,1790156392,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":29,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145},1099514068365,"https://ap-avatar.wpscdn.com/avatar/10000253d8d9f28188e?_k=1776742907772140068","Review began 12/31/2025  \nReview ended 02/07/2026  \nPublished 02/11/2026  \n© Copyright 2026  \nMainer et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0. , which permits unrestricted use , distribution , and reproduction in any medium , provided the original author and source are credited.  \nDOI: 10.7759/cureus.103428  \nOpen Access Case Report  \nBreast Cancer Metastasis with a Ureteral Obstruction and Bladder Mass  \nSasha Mainer 1 , Hannah Lachmayr 1, Benjamin Lemon 2, Wylly Killorin 3  \n1. Urology, Mercer University School of Medicine, Columbus, USA 2. Urology, Mercer University School of Medicine, Valdosta, USA 3. Urology, St. Francis Hospital, Columbus, USA  \nCorresponding author: Sasha Mainer, [sasha.adaiah.mainer@live.mercer.edu](sasha.adaiah.mainer@live.mercer.edu)  \nAbstract  \nBreast cancer is the most common cause of cancer mortality in females globally, and a significant proportion of patients develop metastatic disease. Common metastatic sites of breast cancer include bone, lung, liver, and brain. Secondary neoplasms (metastases from other primary sites) represent a minority of all malignant bladder tumors  \nIn this report, we describe a case of breast cancer metastasis with ureteral obstruction and bladder mass in a 60-year-old African-American female. For over a decade, this patient was asymptomatic and had been under surveillance following bilateral radical mastectomy for invasive ductal carcinoma (IDC) with adjuvant chemoradiotherapy. Unrelated imaging revealed an incidental finding of right hydronephrosis. Subsequent cystoscopy revealed a bladder mass obstructing the right ureteral orifice. Transurethral resection of a bladder tumor and ureteral stent placement were performed, and the pathology findings favored metastatic breast cancer.  \nThe details of the case are intended to help further knowledge of urinary bladder metastases. This case is unusual in that the patient was asymptomatic, her breast cancer type is associated with a lower incidence of bladder metastases, and the bladder was the solitary location of metastasis.  \nCategories: Urology, Obstetrics/Gynecology, Oncology  \nKeywords: breast cancer metastasis, hydronephrosis, invasive ductal carcinoma, metastasis to bladder, metastatic breast carcinoma, ureteral obstruction  \nIntroduction  \nBreast cancer is the most common cancer in women globally. About one in eight women in the United States will be diagnosed with invasive breast cancer, and the median age at the time of breast cancer diagnosis is 62 years [1] . The five-year relative survival rate of all stages of breast cancer is 91%, while that of distant stages is 32%[1] . Black and American Indian/Alaska Native women are most likely to be diagnosed with regionalor distant-stage breast cancer, rather than localized-stage breast cancer [1] .  \nMost breast cancer is sporadic (90% to 95%), and only 5% to 10% of patients have an identifiable genetic mutation [2] . Gene mutation is most common in the genes BRCA1 and BRCA2 [2] . The histologic types of invasive breast cancer include ductal adenocarcinoma, lobular carcinoma, mucinous carcinoma, tubular carcinoma, and medullary carcinoma. Invasive ductal carcinoma (IDC) comprises 50% to 75% of all invasive breast cancers. Breast cancer subtypes can be further classified based on immunohistochemical expression of hormone receptors, which include estrogen receptor positive (ER+), progesterone receptor positive (PR+), and human epidermal growth factor receptor positive (HER2+) . Additionally, the Ki-67 antigen is a cellular marker of proliferation.  \nBreast cancer metastases are not uncommon. Though only 6% of breast cancers are metastatic at the time of diagnosis [3], about 30% of patients initially diagnosed with earlier stages of breast cancer eventually develop recurrent or metastatic disease. Common breast cancer metastatic sites are the bone, lung, liver, and brain [4-5]. Metastases to t","cbCaifqtmGQ8mXG4","https://ap.wps.com/l/cbCaifqtmGQ8mXG4","pdf",1882089,"English","# Abstract\n# Introduction\n# Case Presentation","[{\"question\":\"What makes this case of breast cancer metastasis unusual?\",\"answer\":\"The patient remained asymptomatic for over a decade, and the bladder was the solitary metastatic site associated with ureteral obstruction. Bladder metastases are also uncommon, and many reported cases involve invasive lobular carcinoma rather than invasive ductal carcinoma.\"},{\"question\":\"How was the bladder mass and ureteral obstruction diagnosed?\",\"answer\":\"Incidental imaging revealed right hydronephrosis. Subsequent cystoscopy showed a bladder mass obstructing the right ureteral orifice, and transurethral resection plus ureteral stent placement were performed.\"},{\"question\":\"How did clinicians determine the bladder lesion was metastatic breast cancer?\",\"answer\":\"Pathology findings favored metastatic breast cancer, supported by immunohistochemical markers consistent with the primary invasive ductal carcinoma.\"}]","Breast Cancer Metastasis with a Ureteral Obstruction and Bladder Mass | PDF",1790125519,15]