[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-156459-105":59,"doc-detail-156459-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","brainstem-and-spinal-arachnoiditis-ossificans-associated-with-neurocysticercosis-a-case-report","Brainstem and Spinal Arachnoiditis Ossificans Associated With Neurocysticercosis - A Case Report","","Arachnoiditis ossificans (AO) is an extremely rare condition linked to spinal cord compression and severe neurological deficits through inflammatory and compressive mechanisms. The report describes a 65-year-old woman with neurocysticercosis diagnosed eight years earlier, complicated by obstructive hydrocephalus treated with bilateral ventriculoperitoneal shunts. She developed lower-limb paresis; imaging showed large calcified subdural plaques and she improved after high-dose steroid therapy.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/brainstem-and-spinal-arachnoiditis-ossificans-associated-with-neurocysticercosis-a-case-report/156459/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/brainstem-and-spinal-arachnoiditis-ossificans-associated-with-neurocysticercosis-a-case-report/156459.png","ImageObject",300,407,{"name":92,"@type":93},"Cipher","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-03","2026-08-28",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is arachnoiditis ossificans (AO) and how does it affect the nervous system?","Question",{"text":112,"@type":113},"AO is a very rare condition characterized by calcified plaques in the arachnoid space. In the spinal canal, it can compress the spinal cord and lead to multiple neurological symptoms.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What prior condition was present in the patient and how was it managed?",{"text":117,"@type":113},"The patient had neurocysticercosis diagnosed eight years earlier, which led to obstructive hydrocephalus. Treatment included bilateral ventriculoperitoneal shunting twice prior to the current presentation.",{"name":119,"@type":110,"acceptedAnswer":120},"How was the diagnosis supported and what treatment was given?",{"text":121,"@type":113},"CT demonstrated large calcified subdural spinal plaques, and CT myelography showed irregular partial filling compatible with AO. High-dose steroids were initiated, leading to clinical improvement after the third day.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},156459,1787959322,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":129,"read_time":143,"preview_page_count":4},687208528416,"https://ap-avatar.wpscdn.com/davatar_9964176cb1d06d4a9deccf72a44ae3dc","Open Access Case  \nReport DOI: 10.7759/cureus.46157  \nReview began 09/18/2023  \nReview ended 09/25/2023  \nPublished 09/28/2023  \n© Copyright 2023  \nMondragon-Soto et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0. , which permits unrestricted use , distribution , and reproduction in any medium , provided the original author and source are credited.  \nBrainstem and Spinal Arachnoiditis Ossificans Associated With Neurocysticercosis: A Case Report  \nMichel G. Mondragon-Soto 1 , Jaime Jesus Martinez Anda 2 , Jose Angel Romero Figueroa 3 , Jose Alfredo Gonzalez Soto 4 , Roberto A. De Leo Vargas 2  \n1. Department of Neurosurgery, National Institute of Neurology and Neurosurgery “Dr. Manuel Velasco Suárez”, Mexico City, MEX 2. Department of Neurosurgery, American British Cowdray Neurological Center, Mexico City, MEX 3. Department of Radiology, American British Cowdray Neurological Center, Mexico City, MEX 4. School of Medicine, Metropolitan Autonomous University, Mexico City, MEX  \nCorresponding author: Jose Alfredo Gonzalez Soto, [alfredo.glz.soto@gmail.com](alfredo.glz.soto@gmail.com)  \nAbstract  \nArachnoiditis ossificans (AO), a very rare entity that can cause severe neurological deficit, is associated with an inflammatory response and compressive effect on the spinal cord.  \nA 65-year-old woman with diagnosis of arachnoiditis ossificans, who had a past medical history of neurocysticercosis diagnosed eight years before the actual onset that was accompanied by obstructive hydrocephalus and required bilateral ventriculoperitoneal shunts, presented with lower limb paresis. The spinal CT reported large calcified subdural spinal plaques. She was treated with high-dose steroids with subsequent improvement of the clinical manifestations.  \nSpinal neurocysticercosis is a rare manifestation of this disease, although the Mexican population is especially prone to it, due to the endemic presence of this entity, it can provoke spinal arachnoiditis. We conclude that the chronic inflammation of the spinal meninges induced by the cysticercosis could encourage the arachnoid cells to go through osteoblastic metaplasia with consequent production of thick calcium deposits, such as those found in AO. Thus it may be associated with AO. We present, to our knowledge, the first patient with AO-associated neurocysticercosis.  \nCategories: Neurology, Neurosurgery, Infectious Disease  \nKeywords: brainstem, spine, ossification, neurocysticercosis, arachnoiditis ossificans  \nIntroduction  \nArachnoiditis ossificans (AO) is a very rare condition in which the subdural arachnoid space has calcified plaques associated with arachnoiditis; in the spinal canal, it causes direct compression of the spinal cord which can originate several neurological symptoms. It differs from chronic spinal arachnoiditis by presenting with chronic proliferative changes in the meninges associated with replacement of large spinal arachnoid membranes by dense calcifications similar to bone, and an ossified shell that encases the spinal cord [1] .  \nVery few cases of arachnoiditis ossificans have been previously described in the literature [2] . To our knowledge, our patient is the first case of AO associated with brainstem and spinal neurocysticercosis.  \nCase Presentation  \nA 65-year-old female presented to the emergency room with gait instability and nausea for 48 hours before admission. She had past medical history of neurocysticercosis eight years before being diagnosed by a noncontrast brain CT scan, a condition which resulted in hydrocephalus, and was treated with bilateral ventriculoperitoneal shunting twice several years prior to the present clinical manifestations.  \nOn examination, she had bilateral lower extremity paresis (4/5 bilaterally), proprioceptive impairment was evident starting from the T4 dermatome, hyperreflexia and positive Babinski sign in both lower limbs; ataxic gait was also present. The Brain ","cbCaigQ5CaxzL3cX","https://ap.wps.com/l/cbCaigQ5CaxzL3cX","pdf",484594,"English","# Introduction\n## Case Presentation\n## Imaging Findings\n## Treatment and Outcome","[{\"question\":\"What is arachnoiditis ossificans (AO) and how does it affect the nervous system?\",\"answer\":\"AO is a very rare condition characterized by calcified plaques in the arachnoid space. In the spinal canal, it can compress the spinal cord and lead to multiple neurological symptoms.\"},{\"question\":\"What prior condition was present in the patient and how was it managed?\",\"answer\":\"The patient had neurocysticercosis diagnosed eight years earlier, which led to obstructive hydrocephalus. Treatment included bilateral ventriculoperitoneal shunting twice prior to the current presentation.\"},{\"question\":\"How was the diagnosis supported and what treatment was given?\",\"answer\":\"CT demonstrated large calcified subdural spinal plaques, and CT myelography showed irregular partial filling compatible with AO. High-dose steroids were initiated, leading to clinical improvement after the third day.\"}]","Brainstem and Spinal Arachnoiditis Ossificans Associated With Neurocysticercosis - A Case Report | PDF",13]