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FISHER PATRICK J. HEAGERTY THOMAS LUMLEY  \nDepartment of Biostatistics and Department of Environmental and Occupational Health Sciences University of Washington Seattle, Washington  \nA JOHN WILEY & SONS, INC., PUBLICATION  \nCopyright 􀀁 2004 by John Wiley & Sons, Inc. All rights reserved.  \nPublished by John Wiley & Sons, Inc., Hoboken, New Jersey.  \nPublished simultaneously in Canada.  \nNo part of this publication may be reproduced, stored in a retrieval system, or transmitted in any form or by any means, electronic, mechanical, photocopying, recording, scanning, or otherwise, except as permitted under Section 107 or 108 of the 1976 United States Copyright Act, without either the prior written permission of the Publisher, or authorization through payment of the appropriate per-copy fee to the Copyright Clearance Center, Inc., 222 Rosewood Drive, Danvers, MA 01923, 978-750-8400, fax 978-646-8600, or on the web [at www.copyright.com. Requests](at www.copyright.com. Requests) to the Publisher for permission should be addressed to the Permissions Department, John Wiley & Sons, Inc., 111 River Street, Hoboken, NJ 07030,(201) 748-6011, fax (201) 748-6008 .  \nLimit of Liability/Disclaimer of Warranty: While the publisher and author have used their best efforts in preparing this book, they make no representations or warranties with respect to the accuracy or completeness of the contents of this book and specifically disclaim any implied warranties of merchantability or fitness for a particular purpose. No warranty may be created or extended by sales representatives or written sales materials. The advice and strategies contained herein may not be suitable for your situation. You should consult with a professional where appropriate. Neither the publisher nor author shall be liable for any loss of profit or any other commercial damages, including but not limited to special, incidental, consequential, or other damages.  \nFor general information on our other products and services please contact our Customer Care Department within [the U.S. at](the U.S. at) 877-762-2974, outside [the U.S. at](the U.S. at) 317-572-3993 or fax 317-572-4002 .  \nWiley also publishes its books in a variety of electronic formats. Some content that appears in print, however, may not be available in electronic format.  \nLibrary of Congress Cataloging-in-Publication Data:  \nBiostatistics: a methodology for the health sciences / Gerald van Belle ... [et al.]– 2nd ed.  \n[p. cm](p. cm).–(Wiley series in probability and statistics) First ed. published in 1993, entered under Fisher, Lloyd.  \nIncludes bibliographical references and index.  \nISBN 0-471-03185-2 (cloth)  \n1. Biometry. I. Van Belle, Gerald. II. Fisher, Lloyd, 1939– Biostatistics. III. Series.  \nQH323.5.B562 2004 610′.1′ 5195–dc22  \n2004040491  \nPrinted in the United States of America.  \n10 9 8 7 6 5 4 3 2 1  \nAd majorem Dei gloriam  \nContents  \nPreface to the First Edition ix  \nPreface to the Second Edition xi  \n1. Introduction to Biostatistics 1  \n2. Biostatistical Design of Medical Studies 10  \n3. Descriptive Statistics 25  \n4. Statistical Inference: Populations and Samples 61  \n5. One-and Two-Sample Inference 117  \n6. Counting Data 151  \n7. Categorical Data: Contingency Tables 208  \n8. Nonparametric, Distribution-Free, and Permutation Models:  \nRobust Procedures 253  \n9. Association and Prediction: Linear Models with One  \nPredictor Variable 291  \n10. Analysis of Variance 357  \n11. Association and Prediction: Multiple Regression Analysis  \nand Linear Models with Multiple Predictor Variables 428  \n12. Multiple Comparisons 520  \n13. Discrimination and Classification 550  \n14. Principal Component Analysis and Factor Analysis 584  \nviii CONTENTS  \n15. Rates and Proportions 640  \n16. Analysis of the Time to an Event: Survival Analysis 661  \n17. Sample Sizes for Observational Studies 709  \n18. Longitudinal Data Analysi","cbCaihJpHkiPdaGS","https://ap.wps.com/l/cbCaihJpHkiPdaGS","pdf",8394496,888,"English","# Preface\n# Contents\n## 1. Introduction to Biostatistics\n## 2. Biostatistical Design of Medical Studies\n## 3. Descriptive Statistics\n## 4. Statistical Inference: Populations and Samples\n## 5. One-and Two-Sample Inference\n## 6. Counting Data\n## 7. Categorical Data: Contingency Tables\n## 8. Nonparametric, Distribution-Free, and Permutation Models: Robust Procedures\n## 9. Association and Prediction: Linear Models with One Predictor Variable\n## 10. Analysis of Variance\n## 11. Association and Prediction: Multiple Regression Analysis and Linear Models with Multiple Predictor Variables\n## 12. Multiple Comparisons\n## 13. Discrimination and Classification\n## 14. Principal Component Analysis and Factor Analysis\n## 15. Rates and Proportions\n## 16. Analysis of the Time to an Event: Survival Analysis\n## 17. Sample Sizes for Observational Studies\n## 18. Longitudinal Data Analysis\n## 19. Randomized Clinical Trials\n## 20. Personal Postscript\n# Appendix","[{\"question\":\"Who is the book written for?\",\"answer\":\"The book targets readers learning to apply statistical methods to biomedical sciences, including those with no prior statistics training and basic mathematical knowledge through algebra.\"},{\"question\":\"What kinds of data and models are covered?\",\"answer\":\"It addresses descriptive statistics, inferential methods, one- and two-sample inference, counting and categorical data (contingency tables), nonparametric/distribution-free and permutation models, and robust procedures.\"},{\"question\":\"Does the book include study designs and clinical research topics?\",\"answer\":\"Yes. It includes biostatistical design of medical studies, randomized clinical trials, sample size considerations for observational studies, survival analysis, and longitudinal data analysis.\"}]","Biostatistics - A Methodology for the Health Sciences - Second Edition | PDF",1789975239,2238]