[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-217257-en":3,"doc-seo-217257-105":29,"detail-sidebar-cat-0-en-105":95},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":20,"is_deleted":4,"is_public":20,"is_downloadable":20,"audit_status":20,"page_count":21,"language":22,"language_code":23,"site_id":24,"html_lang":23,"table_of_contents":25,"faqs":26,"seo_title":27,"seo_description":14,"update_tm":28,"read_time":11},217257,5909887256941,"Mason","https://ap-avatar.wpscdn.com/davatar_9964176cb1d06d4a9deccf72a44ae3dc",8,"Research & Report","Bilateral sialocele associated with osseous metaplasia in a dog - Case Report","Sialocele is a saliva-filled lesion delimited by granulation tissue and commonly seen in canine salivary glands. A 12-year-old mixed-breed male dog presented with a cervical swelling; aspiration yielded saliva and the case was managed with referral for sialoadenectomy. Surgery revealed bilateral sialoceles with stony material delimiting both lesions. Histopathology showed cavities lacking epithelial delimitation, with osseous metaplasia and chronic inflammation, supporting bilateral sialocele associated with osseous metaplasia.","Bilateral sialocele associated with osseous metaplasia in a dog  \nBraz J Vet Pathol, 2023, 16(3), 225-227  \nDOI: [https://10.24070/bjvp.1983-0246.v16i3p225-227](https://10.24070/bjvp.1983-0246.v16i3p225-227)  \n225  \nCase Report  \nBilateral sialocele associated with osseous metaplasia in a dog  \nJamile M Garcia 1 *, Luiz A S Silva 1, Nathalia S R Elias2, Andressa G C Nitrini2, Ticiana B Ervedosa 1,  \nMaria Lucia Z Dagli 1, Claudia Momo 1  \n1 Serviço de Patologia Animal, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo (USP), São Paulo, SP, Brazil  \n2 Departamento de Cirurgia, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo (USP), São Paulo, SP, Brazil  \n*Corresponding author: [jamile.garcia@usp.br](jamile.garcia@usp.br)[ ](jamile.garcia@usp.br)Submitted: July 26th, 2023. Accepted: September 23rd, 2023.  \nAbstract  \nSialocele is a lesion characterized by a cavity filled with saliva and delimited by granulation tissue and is the most commonly observed condition in dogs’ salivary glands. A cervical swelling was observed in a male, mixed breed, 12-year-old dog. When punctured, the local was filled with saliva. The animal was referred for sialoadenectomy, and bilateral involvement was observed, with stony material delimiting the sialoceles on both sides. Samples were sent for histopathological examination, which showed cavity areas without epithelial delimitation, with osseous metaplasia and chronic inflammation. Such characteristics allowed the diagnosis of bilateral sialocele associated with osseous metaplasia. The presence ofosseous metaplasia in sialoceles is extremely rare, with only four other cases described, which makes it difficult to reach conclusions related to epidemiology and pathogenesis.  \nKeywords: salivary gland, salivary mucocele, osseous metaplasia, canine, pathology.  \nIntroduction  \nSalivary glands secrete saliva and are located indifferent regions of the head and neck (5, 15) . They vary in number and location among the species, but all of them have the parotid, mandibular, and sublingual glands as their main glands. In the case of carnivores, the zygomatic glands are also added (5) .  \nSialocele is an accumulation of saliva in a cavity surrounded by granulation tissue (11, 14) . Such accumulation is always located near a salivary gland or a ruptured duct (11) . The article reports an unusual case ofosseous metaplasia ina cervical sialocele. This study is the first known report of this condition being described bilaterally, to the best of the author’s knowledge.  \nCase description  \nA 12-year-old mixed-breed male dog was admitted to the Veterinary Teaching Hospital of the School of Veterinary  \nMedicine and Animal Science from the University of São Paulo (HOVET – FMVZ – USP), São Paulo, Brazil, due toa painless and firm submandibular swelling measuring 5.5 x 5.0 x 4.5 cm. An aqueous fluid was aspirated through fine needle aspiration, and the case was clinically diagnosed assialocele. Initial treatment consisted of carprofen 25mg twice a day and warm compresses. Two months later, after recurrence, the animal was referred for bilateral sialoadenectomy. During the procedure, close to the left mandibular salivary gland, a cavity area delimited by hard consistency tissue was observed, filled with approximately 48 ml of blood-tinged fluid. Inside the cavity, it was noted the presence of sialoliths. The right mandibular salivary gland had a small cavity area filled with a light amount of saliva and a plaque similar to that observed in the left sialocele. Samples were submitted to the Animal Pathology Service of the same institution for histopathological examination. The sialocele samples needed to undergo decalcification. The fragments were fixed in 10% formalin and routinely processed to obtain histological slides stained with hematoxylin and eosin. In the histopathological analysis, the walls of the sialoceles on both sides had mature  \n[Brazilian Journal of Veterinar","cbCaihrmFNmOPoZZ","https://ap.wps.com/l/cbCaihrmFNmOPoZZ","pdf",230638,1,3,"English","en",105,"# Abstract\n# Introduction\n# Case description\n# Discussion","[{\"question\":\"What clinical finding led to the diagnosis of sialocele in this dog?\",\"answer\":\"A male mixed-breed 12-year-old dog showed a painless firm submandibular/cervical swelling. Fine needle aspiration revealed saliva, supporting a clinical diagnosis of sialocele.\"},{\"question\":\"What did surgery reveal about the lesions?\",\"answer\":\"Bilateral sialoadenectomy showed cavity areas with hard consistency tissue and blood-tinged fluid near the mandibular salivary glands, including sialoliths on the left side.\"},{\"question\":\"How did histopathology confirm osseous metaplasia within the sialocele?\",\"answer\":\"Histology demonstrated cavity areas without epithelial lining, with mature bone tissue (osseous metaplasia) surrounded by fibrosis, hemorrhage, and chronic inflammation, allowing diagnosis of bilateral sialocele associated with osseous metaplasia.\"}]","Bilateral sialocele associated with osseous metaplasia in a dog - Case Report | PDF",1788831736,{"code":4,"msg":30,"data":31},"ok",{"site_id":24,"language":23,"slug":32,"title":13,"keywords":33,"description":14,"schema_data":34,"social_meta":90,"head_meta":92,"extra_data":94,"updated_unix":28},"bilateral-sialocele-associated-with-osseous-metaplasia-in-a-dog-case-report","",{"@graph":35,"@context":89},[36,52,72],{"@type":37,"itemListElement":38},"BreadcrumbList",[39,43,47,49],{"item":40,"name":41,"@type":42,"position":20},"https://docshare.wps.com","Home","ListItem",{"item":44,"name":45,"@type":42,"position":46},"https://docshare.wps.com/document/","Document",2,{"item":48,"name":12,"@type":42,"position":21},"https://docshare.wps.com/document/research-report/",{"item":50,"name":13,"@type":42,"position":51},"https://docshare.wps.com/document/bilateral-sialocele-associated-with-osseous-metaplasia-in-a-dog-case-report/217257/",4,{"url":50,"name":13,"@type":53,"image":54,"author":59,"headline":13,"publisher":61,"fileFormat":64,"inLanguage":23,"description":14,"dateModified":65,"datePublished":66,"encodingFormat":64,"isAccessibleForFree":67,"interactionStatistic":68},"DigitalDocument",{"url":55,"@type":56,"width":57,"height":58},"https://docshare.wps.com/thumbnails/bilateral-sialocele-associated-with-osseous-metaplasia-in-a-dog-case-report/217257.png","ImageObject",300,407,{"name":9,"@type":60},"Person",{"url":40,"name":62,"@type":63},"DocShare","Organization","application/pdf","2026-09-11","2026-09-08",true,{"@type":69,"interactionType":70,"userInteractionCount":20},"InteractionCounter",{"@type":71},"ViewAction",{"@type":73,"mainEntity":74},"FAQPage",[75,81,85],{"name":76,"@type":77,"acceptedAnswer":78},"What clinical finding led to the diagnosis of sialocele in this dog?","Question",{"text":79,"@type":80},"A male mixed-breed 12-year-old dog showed a painless firm submandibular/cervical swelling. Fine needle aspiration revealed saliva, supporting a clinical diagnosis of sialocele.","Answer",{"name":82,"@type":77,"acceptedAnswer":83},"What did surgery reveal about the lesions?",{"text":84,"@type":80},"Bilateral sialoadenectomy showed cavity areas with hard consistency tissue and blood-tinged fluid near the mandibular salivary glands, including sialoliths on the left side.",{"name":86,"@type":77,"acceptedAnswer":87},"How did histopathology confirm osseous metaplasia within the sialocele?",{"text":88,"@type":80},"Histology demonstrated cavity areas without epithelial lining, with mature bone tissue (osseous metaplasia) surrounded by fibrosis, hemorrhage, and chronic inflammation, allowing diagnosis of bilateral sialocele associated with osseous metaplasia.","https://schema.org",{"og:url":50,"og:type":91,"og:title":13,"og:site_name":62,"og:description":14},"article",{"robots":93,"canonical":50},"index,follow",{"doc_id":7,"site_id":24},{"code":4,"msg":5,"data":96},[97,101,105,109,114,119,124,127,132,135,139],{"id":20,"doc_module":4,"doc_module_name":45,"category_name":98,"show_sort_weight":99,"slug":100},"Story & Novel",90,"story-novel",{"id":46,"doc_module":4,"doc_module_name":45,"category_name":102,"show_sort_weight":103,"slug":104},"Literature",80,"literature",{"id":51,"doc_module":4,"doc_module_name":45,"category_name":106,"show_sort_weight":107,"slug":108},"Exam",70,"exam",{"id":110,"doc_module":4,"doc_module_name":45,"category_name":111,"show_sort_weight":112,"slug":113},5,"Comic",60,"comic",{"id":115,"doc_module":4,"doc_module_name":45,"category_name":116,"show_sort_weight":117,"slug":118},6,"Technology",50,"technology",{"id":120,"doc_module":4,"doc_module_name":45,"category_name":121,"show_sort_weight":122,"slug":123},7,"Healthcare",40,"healthcare",{"id":11,"doc_module":4,"doc_module_name":45,"category_name":12,"show_sort_weight":125,"slug":126},30,"research-report",{"id":128,"doc_module":4,"doc_module_name":45,"category_name":129,"show_sort_weight":130,"slug":131},9,"Religion & Spirituality",20,"religion-spirituality",{"id":130,"doc_module":4,"doc_module_name":45,"category_name":133,"show_sort_weight":130,"slug":134},"World Cup","world-cup",{"id":136,"doc_module":4,"doc_module_name":45,"category_name":137,"show_sort_weight":136,"slug":138},10,"Lifestyle","lifestyle",{"id":140,"doc_module":4,"doc_module_name":45,"category_name":141,"show_sort_weight":110,"slug":142},19,"General","general"]