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This case report describes the first documented instance of metastatic BCC (mBCC) to the stomach, illustrating the need to consider atypical metastatic sites. A 52-year-old man with recurrent BCC and extensive bone metastases developed progressive dysphagia and neurologic symptoms.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/beyond-the-skin-metastatic-basal-cell-carcinoma-in-the-stomach-a-case-report/406347/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/beyond-the-skin-metastatic-basal-cell-carcinoma-in-the-stomach-a-case-report/406347.png","ImageObject",300,407,{"name":92,"@type":93},"Rizky","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What makes gastric metastasis from basal cell carcinoma exceptionally rare?","Question",{"text":112,"@type":113},"Gastric metastases from metastatic BCC occur at very low rates and have rarely been documented, making stomach involvement an atypical metastatic site compared with more common locations such as lymph nodes, lungs, and bones.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What symptoms did the patient present with in this case?",{"text":117,"@type":113},"The 52-year-old male presented with progressive dysphagia, cranial neuropathies, and generalized weakness, in the context of recurrent BCC and known metastatic disease to the bone.",{"name":119,"@type":110,"acceptedAnswer":120},"How was the diagnosis of metastatic BCC to the stomach confirmed?",{"text":121,"@type":113},"Gastroscopy showed subepithelial gastric lesions, and biopsies confirmed metastatic BCC, establishing an previously unreported site of dissemination.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},406347,1790911866,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":34,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},962085564807,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","| W | J | G | World Journal of\u003Cbr>Gastroenterology |\n| --- | --- | --- | --- |\n\nSubmit a Manuscript: [https://www.f6publishing.com](https://www.f6publishing.com) World J Gastroenterol 2025 December 14; 31(46): 112010  \nDOI: 10.3748/wjg.v31.i46.112010 ISSN 1007-9327 (print) ISSN 2219-2840 (online)  \nCASE REPORT  \nBeyond the skin-metastatic basal cell carcinoma in the stomach: A case report  \nShukria Ahmadi, Ishraq Joarder, Fahd Jowhari  \nSpecialty type: Gastroenterology and hepatology  \nProvenance and peer review:  \nUnsolicited article; Externally peer reviewed.  \nPeer-review model: Single blind  \nPeer-review report’s classification Scientific Quality: Grade B, Grade B, Grade B  \nNovelty: Grade A, Grade B, Grade B  \nCreativity or Innovation: Grade B, Grade B, Grade B  \nScientific Significance: Grade B, Grade B, Grade B  \nP-Reviewer: Gu CH, Academic Fellow, Lecturer, China; Shi B, PhD, China  \nReceived: July 17, 2025  \nRevised: August 5, 2025  \nAccepted: October 31, 2025  \nPublished online: December 14, 2025  \nProcessing time: 147 Days and 4.2 Hours  \nShukria Ahmadi, Department of Internal Medicine, University of Calgary, Calgary T2N 1N4, Alberta, Canada  \nIshraq Joarder, Department of Radiology, University of Calgary, Calgary T2N 1N4, Alberta, Canada  \nFahd Jowhari, Division of Gastroenterology, Kelowna General Hospital, University of British  \nColumbia Okanagan, Kelowna V1Y6J6, British Columbia, Canada Co-first authors: Shukria Ahmadi and Ishraq Joarder.  \nCorresponding author: Fahd Jowhari, MD, FRCPC, Division of Gastroenterology, Kelowna General Hospital, University of British Columbia Okanagan, 564 Leon Avenue, Kelowna V1Y6J6, British Columbia, [Canada.](Canada. fahd@kelownagi.ca)[ fahd@kelownagi.ca](Canada. fahd@kelownagi.ca)  \nAbstract  \nBACKGROUND  \nBasal cell carcinoma (BCC) is the most prevalent skin cancer, characterized by indolent growth and low metastatic rates. When metastatic BCC (mBCC) does occur, it most commonly involves lymph nodes, lungs, and bones, with metastases to other sites being exceptionally rare. This case reports the first documented instance of mBCC to the stomach, highlighting the importance of considering atypical metastatic sites, and the challenges associated with diagnosis and management.  \nCASE SUMMARY  \nA 52-year-old male with recurrent BCC and known mBCC to the bone presented with progressive dysphagia, cranial neuropathies and generalized weakness. He had been treated with immune checkpoint inhibitors, with intermittent therapy modifications due to treatment related toxicities. His past history was notable for malignant perineural invasion, radiotherapy for osseous metastases, immune checkpoint inhibitor-induced enteritis, and osteonecrosis of the jaw. Gastroscopy revealed subepithelial gastric lesions, and biopsies confirmed mBCC-a previously unreported site of disease dissemination. A multidisciplinary team involving gastroenterology, oncology, neurology, and palliative care guided his management. Given his declining functional status and poor prognosis, he was ultimately transitioned to hospice care.  \n WJG  [https://www.wjgnet.com](https://www.wjgnet.com) 1 December 14, 2025  Volume 31  Issue 46   \nAhmadi S et al. Gastric metastasis of BCC  \nCONCLUSION  \nClinicians should consider atypical metastatic sites in advanced BCC. A multidisciplinary approach remains essential for timely diagnosis and coordinated management.  \nKey Words: Basal cell carcinoma; Metastases; Gastric lesions; Immune checkpoint inhibitor; Immune-related adverse events; Gastric subepithelial lesions; Case report  \n©The Author(s) 2025. Published by Baishideng Publishing Group Inc. All rights reserved.  \nCore Tip: Metastatic basal cell carcinoma (BCC) rarely involves visceral organs, and gastric metastases have never been previously reported. We present the first documented case of metastatic BCC to the stomach in a patient with extensive bone metastases, highlighting the diagnostic challenges associated with this unu","cbCaiez5RsvdSzha","https://ap.wps.com/l/cbCaiez5RsvdSzha","pdf",3373690,"English","# Case report\n## Background\n## Case summary\n## Conclusion\n## Introduction","[{\"question\":\"What makes gastric metastasis from basal cell carcinoma exceptionally rare?\",\"answer\":\"Gastric metastases from metastatic BCC occur at very low rates and have rarely been documented, making stomach involvement an atypical metastatic site compared with more common locations such as lymph nodes, lungs, and bones.\"},{\"question\":\"What symptoms did the patient present with in this case?\",\"answer\":\"The 52-year-old male presented with progressive dysphagia, cranial neuropathies, and generalized weakness, in the context of recurrent BCC and known metastatic disease to the bone.\"},{\"question\":\"How was the diagnosis of metastatic BCC to the stomach confirmed?\",\"answer\":\"Gastroscopy showed subepithelial gastric lesions, and biopsies confirmed metastatic BCC, establishing an previously unreported site of dissemination.\"}]","Beyond the skin - metastatic basal cell carcinoma in the stomach - A case report | PDF",1790565040,18]