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As mentioned in our article, the early neurodegenerative changes of the retina in diabetic subjects with no diabetic retinopathy were shown as a decrease in the thickness of the ganglion cell layer + internal plexiform layer. This finding, according to comment of Thiago Gonsalves, could be due to a disruptions in glutamate metabolism in the retina.  \nData availability statement  \nData sharing isnot applicable to this article as no datasets were generated or analyzed during the current study.  \nFinancial support and sponsorship  \nNil.  \nConflicts of interest  \nThe author declares that there are no conflicts of interests of this paper.  \nMonireh Mahjoob*  \nHealth Promotion Research Center, Department of Optometry, Rehabilitation Sciences Faculty, Zahedan University of Medical Sciences, Zahedan, Iran  \n*Address for correspondence:  \nDr. Monireh Mahjoob,  \nHealth Promotion Research Center, Department of Optometry, Rehabilitation Sciences Faculty, Zahedan University of Medical Sciences, Zahedan, Iran.  \n[E-mail: mahjoob_opt@yahoo.com](E-mail: mahjoob_opt@yahoo.com)  \nSubmission: 07-10-2024  \nAccepted: 03-11-2024  \nPublished: 26-03-2025  \nReference  \n1. Martins TG, Martins DG. Comment on optical coherence tomography and contrast sensitivity in early diabetic retinopathy. Taiwan J Ophthalmol 2025;14:666-667 .  \nHow to cite this article: Mahjoob M. Author’s response to letter of editor for “Optical coherence tomography and contrast sensitivity in early diabetic retinopathy”. Taiwan J Ophthalmol 2025;15:670 .  \n© 2025 Taiwan J Ophthalmol | Published by Wolters Kluwer-Medknow  \n670 © 2025 Taiwan J Ophthalmol | Published by Wolters Kluwer-Medknow","cbCaikEiP8OsrR5H","https://ap.wps.com/l/cbCaikEiP8OsrR5H","pdf",220235,"English","# Author’s response\n## Study findings and interpretation\n## Data availability\n## Financial support and conflicts of interest\n## Correspondence and publication details\n## Reference and citation","[{\"question\":\"What do the comments from Thiago Gonçalves dos Santos Martins confirm?\",\"answer\":\"The author indicates the comments align with confirming the study’s results.\"},{\"question\":\"What retinal change did the study observe in diabetic subjects without diabetic retinopathy?\",\"answer\":\"The author reports decreased thickness of the ganglion cell layer plus internal plexiform layer.\"},{\"question\":\"Is data sharing applicable to this article, and were there financial or conflict disclosures?\",\"answer\":\"Data sharing is not applicable because no datasets were generated or analyzed. The author states financial support is nil and declares no conflicts of interest.\"}]","Author’s response to letter of editor for “Optical coherence tomography and contrast sensitivity in early diabetic retinopathy” | PDF",1790746387]