[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-269568-105":59,"doc-detail-269568-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","astar-research-issue-49-feature-articles-and-research-highlights","A*STAR Research - Issue 49 - Feature articles and research highlights","","A*STAR Research Issue 49 (September–October 2025) compiles scientific feature stories and research highlights across multiple institutes and disciplines. The edition foregrounds integrity and forward-looking discovery, including immunology, neuroscience, bioengineering, genomics, and broader urban solutions. Coverage also extends to energy, food science, fusion energy, language models for dementia care, optics and photonics, sensors, and manufacturing themes such as seeing the invisible and improving materials surfaces.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/astar-research-issue-49-feature-articles-and-research-highlights/269568/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/astar-research-issue-49-feature-articles-and-research-highlights/269568.png","ImageObject",300,407,{"name":92,"@type":93},"Noah","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-16","2026-09-15",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",16,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What is included in A*STAR Research Issue 49?","Question",{"text":113,"@type":114},"The issue includes an editorial section, a cover story, a feature section, and research highlights spanning human health and potential, urban solutions and sustainability, smart nation and digital economy, and manufacturing themes.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"Which months does Issue 49 cover?",{"text":118,"@type":114},"Issue 49 is dated September–October 2025.",{"name":120,"@type":111,"acceptedAnswer":121},"Where can readers access the articles?",{"text":122,"@type":114},"Articles are first published online on the A*STAR Research website and are available free to readers.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},269568,1789453132,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":36,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":130,"read_time":144,"preview_page_count":4},8796095462418,"https://ap-avatar.wpscdn.com/avatar/80000253c1241d02b47?x-image-process=image/resize,m_fixed,w_180,h_180&k=1778826106357471780","[www.research.a-star.edu.sg](www.research.a-star.edu.sg)  \nA*STAR Research is a publication of the Agency for Science, Technology and Research (A*STAR)—Singapore’s lead government agency for fostering world-class scientific research.  \nA*STAR Research is published bimonthly, presenting research highlights and feature articles. All articles are first published online on the A*STAR Research website and available free to all readers. Register online to receive our monthly e-newsletter by email.  \n© 2025 Agency for Science, Technology and Research. This publication may be reproduced in its original form for personal use only. Modification or commercial use without prior permission from the copyright holder is prohibited.  \nA*STAR Research is published for A*STAR by the custom media publishing unit of Wildtype Media Group Pte Ltd.  \nEDITORIAL  \nAgency for Science, Technology and Research  \n1 Fusionopolis Way, Connexis North Tower, \\#20-10 Singapore 138632  \nEditor-in-Chief  \nAndy Hor (DCE(R))  \nEditorial Board  \nMolecular & Cellular Sciences  \nCaroline Wee (A*STAR IMCB) Qi Jing Li (A*STAR IMCB)  \nWeiping Han (A*STAR IMCB) Xinyi Su (A*STAR IMCB)  \nYue Wan (A*STAR GIS)  \nHuman Health & Disease Sciences  \nAnand Andiappan (A*STAR SIgN) Jean Yeung (A*STAR IHDP) Jingmei Li (A*STAR GIS)  \nMarco Vignuzzi (A*STAR IDL) Rachel Watson (A*STAR SRL) Ying Swan Ho (A*STAR BTI)  \nComputer & Data Sciences  \nBasura Fernando (A*STAR IHPC) Yao Zhu (A*STAR IME)  \nYew Soon Ong (SERC)  \nYinping Yang (A*STAR IHPC)  \nManufacturing & Materials Science  \nDi Zhu (A*STAR IMRE)  \nJinghua Teng (A*STAR IMRE) Kui Yao (A*STAR IMRE)  \nSharon Nai (A*STAR SIMTech) Xian Jun Loh (A*STAR IMRE) Yun Zong (RO)  \nDCE(R): Deputy Chief Executive (Research)  \nBMRC: Biomedical Research Council R&TD: Research and Talent Development ISSN 2010-0531  \nUrban Technology & Sustainability  \nJason Lim (A*STAR IMRE)  \nLili Zhang (A*STAR ISCE²)  \nZhi Wei Seh (A*STAR IMRE)  \nAdvisory Board  \nAshok Venkitaraman (BMRC)  \nBarry Halliwell (BMRC)  \nHuck Hui Ng (R&TD)  \nIrene Cheong (I&E)  \nJohn O’Reilly (SERC)  \nKeng Hui Lim (SERC)  \nLisa Ooi (BMRC)  \nYee Chia Yeo (I&E)  \nEarly Career Advisory Board  \nBowei Dong (A*STAR IME)  \nKenneth Lay (A*STAR SRL)  \nShuang Liu (A*STAR IMCB)  \nWan Ru Leow (A*STAR ISCE²)  \nYi-Hao Chan (A*STAR IDL)  \nYong Kiam Tan (A*STAR I²R)  \nCo-Managing Editors  \nKrishnaveni Rajagopal (RO)  \nNafisah Mohamad Ismail (RO)  \nXin Ying Toh (RO)  \nSERC: Science and Engineering Research Council I&E: Innovation and Enterprise  \nRO: Research Office  \nThe Agency for Science, Technology and Research (A*STAR) is Singapore’s lead government agency dedicated to fostering world-class scientific research and talent for a vibrant knowledge-based economy.  \nA*STAR actively nurtures public-sector research and development in biomedical sciences, physical sciences and engineering, and spurs growth in Singapore’s key economic clusters by providing human, intellectual and industrial capital to our partners in industry and the healthcare sector.  \nA*STAR currently oversees the following research institutes, national centres and programmes, and supports extramural research with universities, hospital research centres and other local and international partners:  \nA*STAR Research Institutes (ARES)  \nA*STAR Advanced Remanufacturing and Technology Centre (A*STAR ARTC)  \nA*STAR Bioinformatics Institute (A*STAR BII)  \nA*STAR Bioprocessing Technology Institute (A*STAR BTI)  \nA*STAR Genome Institute of Singapore (A*STAR GIS)  \nA*STAR Infectious Diseases Labs (A*STAR IDL)  \nA*STAR Institute for Human Development and Potential (A*STAR IHDP)  \nA*STAR Institute for Infocomm Research (A*STAR I²R)  \nA*STAR Institute of High Performance Computing (A*STAR IHPC)  \nA*STAR Institute of Materials Research and Engineering (A*STAR IMRE)  \nA*STAR Institute of Microelectronics (A*STAR IME)  \nA*STAR Institute of Molecular and Cell Biology (A*STAR IMCB)  \nA*STAR Institute of Sustainability for Chemicals, Energy and Environmen","cbCaihS8Mk93Qe8O","https://ap.wps.com/l/cbCaihS8Mk93Qe8O","pdf",7381350,"English","# Contents\n## Issue 49 | September – October 2025\n## Editorial\n### Editorial notes\n## Cover Story\n### A lodestar for integrity\n## Feature\n### Driving science to new horizons\n## Research Highlights\n### Immunology: Tired T cells get a power up\n### Neuroscience: Obesity genes also speak for the growing brain\n### Bioengineering: Unraveling sticky situations with antibodies\n### Genomics: Single-cell maps unveil Asia’s immune diversity\n### Urban Solutions and Sustainability\n### Energy: Amplifying hidden faces of aluminium batteries\n### Food Science: Digesting the difference between plant and animal proteins\n### Energy: On the wave to fusion energy\n### Smart Nation and Digital Economy\n### Language Models: A tireless friend in dementia care\n### Optics and Photonics: Rippling new colours from quantum emitters\n### Sensors: SEA-ing into machines’ future life\n### Manufacturing, Trade and Connectivity\n### Optics: Seeing the invisible\n### Materials Science: Washing surface defects away\n### Materials Science: Shaping strength with thinner co","[{\"question\":\"What is included in A*STAR Research Issue 49?\",\"answer\":\"The issue includes an editorial section, a cover story, a feature section, and research highlights spanning human health and potential, urban solutions and sustainability, smart nation and digital economy, and manufacturing themes.\"},{\"question\":\"Which months does Issue 49 cover?\",\"answer\":\"Issue 49 is dated September–October 2025.\"},{\"question\":\"Where can readers access the articles?\",\"answer\":\"Articles are first published online on the A*STAR Research website and are available free to readers.\"}]","A*STAR Research - Issue 49 - Feature articles and research highlights | PDF",101]