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This cross-sectional study analyzed 120 adults (30–60) with HbA1c-defined prediabetes, measuring serum 25(OH)D and glycemic indicators including FBG, HbA1c, and insulin resistance to assess associations.",{"@graph":14,"@context":76},[15,34,55],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/association-between-serum-vitamin-d-levels-and-glycemic-status-in-prediabetic-adults/460283/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/association-between-serum-vitamin-d-levels-and-glycemic-status-in-prediabetic-adults/460283.png","ImageObject",300,407,{"name":42,"@type":43},"awa","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-11-07","2026-09-30",true,{"@type":52,"interactionType":53,"userInteractionCount":26},"InteractionCounter",{"@type":54},"ViewAction",{"@type":56,"mainEntity":57},"FAQPage",[58,64,68,72],{"name":59,"@type":60,"acceptedAnswer":61},"What was the main purpose of the study?","Question",{"text":62,"@type":63},"To examine whether serum vitamin D levels are associated with glycemic status in adults with prediabetes, using measures such as FBG and HbA1c.","Answer",{"name":65,"@type":60,"acceptedAnswer":66},"How were participants diagnosed with prediabetes and classified by vitamin D levels?",{"text":67,"@type":63},"Participants were identified using HbA1c between 5.7% and 6.4%. Serum 25(OH)D was categorized as deficient (\u003C20 ng/mL), insufficient (20–29 ng/mL), and sufficient (≥30 ng/mL).",{"name":69,"@type":60,"acceptedAnswer":70},"What relationships did the study find between vitamin D and glycemic indicators?",{"text":71,"@type":63},"The insufficient vitamin D group showed higher average FBG and higher HbA1c than the sufficient group. Serum 25(OH)D also showed a strong negative correlation with HbA1c (r = –0.42, P \u003C 0.01).",{"name":73,"@type":60,"acceptedAnswer":74},"What does the conclusion suggest for people with prediabetes?",{"text":75,"@type":63},"Low vitamin D is strongly linked to poorer blood sugar management, so checking and correcting vitamin D levels may help delay or avoid type 2 diabetes.","https://schema.org",{"og:url":32,"og:type":78,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":80,"canonical":32},"index,follow",{"doc_id":82,"site_id":7},460283,1790758137,{"code":4,"msg":85,"data":86},"success",[87,91,95,99,104,109,113,118,123,126,130],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":88,"show_sort_weight":89,"slug":90},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":92,"show_sort_weight":93,"slug":94},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":96,"show_sort_weight":97,"slug":98},"Exam",70,"exam",{"id":100,"doc_module":4,"doc_module_name":25,"category_name":101,"show_sort_weight":102,"slug":103},5,"Comic",60,"comic",{"id":105,"doc_module":4,"doc_module_name":25,"category_name":106,"show_sort_weight":107,"slug":108},6,"Technology",50,"technology",{"id":110,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":111,"slug":112},7,40,"healthcare",{"id":114,"doc_module":4,"doc_module_name":25,"category_name":115,"show_sort_weight":116,"slug":117},8,"Research & Report",30,"research-report",{"id":119,"doc_module":4,"doc_module_name":25,"category_name":120,"show_sort_weight":121,"slug":122},9,"Religion & Spirituality",20,"religion-spirituality",{"id":121,"doc_module":4,"doc_module_name":25,"category_name":124,"show_sort_weight":121,"slug":125},"World Cup","world-cup",{"id":127,"doc_module":4,"doc_module_name":25,"category_name":128,"show_sort_weight":127,"slug":129},10,"Lifestyle","lifestyle",{"id":131,"doc_module":4,"doc_module_name":25,"category_name":132,"show_sort_weight":100,"slug":133},19,"General","general",{"code":4,"msg":85,"data":135},{"doc_id":82,"user_id":136,"nickname":42,"user_avatar":137,"doc_module":4,"category_id":110,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":138,"file_id":139,"file_url":140,"file_type":141,"file_size":142,"view_count":26,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":30,"language":143,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":144,"faqs":145,"seo_title":146,"seo_description":12,"update_tm":83,"read_time":114,"preview_page_count":4},3985747858093,"https://ap-avatar.wpscdn.com/davatar_3d24733baf745e90a7e4bdd5f77d97b2","Original Article  \nAssociation Between Serum Vitamin D Levels and Glycemic Status in Prediabetic Adults  \nNitin Wathore ¹, Dibyanshu², Samreen Farooqui3, Tanvi Patel⁴, Sangeeta Gupta⁵, Mayur N. Vasava ⁶  \n1Department of Medicine, Symbiosis Medical College for Women and Symbiosis University Hospital and Research Centre, Symbiosis International (Deemed University),  \nPune, Maharashtra, India, 2Department of Community and Family Medicine, All India Institute of Medical Sciences, Deoghar, Jharkhand, India, 3Department of Basic Medical Sciences (Physiology), College of Medicine, Jazan University, Jazan, Saudi Arabia, 4Department of Anatomy, GMERS Medical College and Hospital, Vadodara, Gujarat, India, 5Department of Physiology, All India Institute of Medical Sciences, Gorakhpur, Uttar Pradesh, India, 6Department of Anesthesiology,  \nDr N. D. Desai Faculty of Medical Science and Research, Dharmsinh Desai University, Nadiad, Gujarat, India  \nSubmitted: 21‑Jun‑2025  \nRevised: 03‑Jul‑2025  \nAccepted: 26‑Jul‑2025  \nPublished: 17‑Dec‑2025  \nAbstract  \nBackground: Vitamin D is very important for insulin secretion and sensitivity, and not getting enough of it has been related to problems with glucose metabolism. Prediabetes is a stage of glucose intolerance that can be reversed. Finding modifiable risk factors, such as a lack of vitamin D, can aid with early intervention. Materials and Methods: A cross‑sectional analytical investigation was done with 120 persons between the ages of 30 and 60 who had been diagnosed with prediabetes based on HbA1c readings between 5.7% and 6.4% . We used a chemiluminescent immunoassay to find out how much 25-hydroxyvitamin D [25(OH)D] was in the serum. We put the participants into three categories based on their vitamin D levels: deficient (\u003C20 ng/mL), insufficient (20–29 ng/mL), and sufficient (≥30 ng/mL) . We looked at glycemic indicators, such as fasting blood glucose (FBG), HbA1c, and homeostatic model assessment of insulin resistance among groups. Results: Out of 120 people, 48 (40%) were low in vitamin D, 44 (36.7%) were not getting enough, and 28 (23.3%) were getting enough. The average FBG was much greater in the group that did not get enough vitamin D (112.3 ± 9.4 mg/dL) than in the group that did (102.1 ± 8.6 mg/dL) (P = 0.003) . In the same way, the average HbA1c levels were 6.3% ±0.2% in the insufficient group and 5.9% ±0.3% in the sufficient group (P = 0.001) . There was a strong negative connection between serum 25(OH)D and HbA1c (r = –0.42, P \u003C 0.01) . Conclusion: A lack of vitamin D is strongly linked to poor blood sugar management in persons who are prediabetic. Checking and fixing vitamin D levels may help those who are at risk of getting type 2 diabetes delay or avoid getting it.  \nKeywords: Glycemic control, HbA1c, insulin resistance, prediabetes, serum 25(OH)D, vitamin D   \nIntroduction  \nrediabetes is a stage of hyperglycemia that is  \nlbsetwareeenhinghoermar thlaanndusdiaualbeticbut .Intotisywethen bin thloode disuabgetairc range. This is an important time to step in since people with prediabetes are more likely to develop type 2 diabetes mellitus (T2DM) and heart problems that go along with it.[1,2] Finding things that can be changed at  \n\n| Access this article online |  |\n| --- | --- |\n| Quick Response Code:\u003Cbr>| Website: [https://journals.lww.com/jpbs](https://journals.lww.com/jpbs) |\n|  | DOI: 10.4103/jpbs.jpbs_1112_25 |\n\nthis stage can be very helpful in stopping or delaying the progression to full‑blown diabetes.  \nVitamin D is a fat‑soluble secosteroid that may change how glucose is used by the body by affecting the  \nAddress for correspondence: Dr. Tanvi Patel,  \nDepartment of Anatomy, GMERS Medical College and Hospital, Gotri, Vadodara, Gujarat, India.  \nE‑mail: [tanvipatel1608@gmail.com](tanvipatel1608@gmail.com)  \nThis is an open access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 License (CC BY-NC-ND), where it is p","cbCaiuNDIoCnCIcK","https://ap.wps.com/l/cbCaiuNDIoCnCIcK","pdf",598498,"English","# Abstract\n# Introduction\n# Materials and Methods","[{\"question\":\"What was the main purpose of the study?\",\"answer\":\"To examine whether serum vitamin D levels are associated with glycemic status in adults with prediabetes, using measures such as FBG and HbA1c.\"},{\"question\":\"How were participants diagnosed with prediabetes and classified by vitamin D levels?\",\"answer\":\"Participants were identified using HbA1c between 5.7% and 6.4%. Serum 25(OH)D was categorized as deficient (\\u003c20 ng/mL), insufficient (20–29 ng/mL), and sufficient (≥30 ng/mL).\"},{\"question\":\"What relationships did the study find between vitamin D and glycemic indicators?\",\"answer\":\"The insufficient vitamin D group showed higher average FBG and higher HbA1c than the sufficient group. Serum 25(OH)D also showed a strong negative correlation with HbA1c (r = –0.42, P \\u003c 0.01).\"},{\"question\":\"What does the conclusion suggest for people with prediabetes?\",\"answer\":\"Low vitamin D is strongly linked to poorer blood sugar management, so checking and correcting vitamin D levels may help delay or avoid type 2 diabetes.\"}]","Association Between Serum Vitamin D Levels and Glycemic Status in Prediabetic Adults | PDF"]