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This study analyzed associations and interactions between EE domains and intrinsic capacity (IC), a World Health Organization framework for functional ability in older adults. Cross-sectional data from 5,454 participants in the English Longitudinal Study of Ageing assessed physical activity, cognitive engagement, and social engagement. Ordinal logistic models adjusted for key demographics found independent positive links of each EE domain with higher IC levels and a cognitive engagement–physical activity interaction.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/association-between-multidimensional-environmental-enrichment-domains-and-intrinsic-capacity-among-older-adults/427700/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/association-between-multidimensional-environmental-enrichment-domains-and-intrinsic-capacity-among-older-adults/427700.png","ImageObject",300,407,{"name":92,"@type":93},"Kyle","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-07","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":29},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is intrinsic capacity in this study?","Question",{"text":112,"@type":113},"Intrinsic capacity (IC) is defined using World Health Organization (WHO) guidance as a holistic framework for assessing functional health that supports independence in older age.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How were environmental enrichment domains measured?",{"text":117,"@type":113},"EE domains were assessed via self-reported physical activity level (high/low), frequency of stimulating cognitive activities, and frequency of social/community interactions.",{"name":119,"@type":110,"acceptedAnswer":120},"What did the study find about the relationship between EE and IC?",{"text":121,"@type":113},"Each EE domain showed significant independent associations with higher IC levels, and an interaction between cognitive engagement and physical activity indicated combined effects beyond individual contributions.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},427700,1791198090,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":29,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":8,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":81},3985741905716,"https://ap-avatar.wpscdn.com/davatar_994ba38a5ba835b3df7d355c54d3ed8d","Innovation in Aging, 2025, Vol. 9, No. S2 785  \neffects. Interactions involving social engagement were not significant. Findings support translating EE concepts into human aging research, highlighting multidimensional lifestyle approaches, especially integrating physical and cognitive activities, to promote healthy aging. Future longitudinal studies and intervention trials are needed to confirm these findings and test the effectiveness of multidimensional EE interventions for optimizing intrinsic capacity and related health outcomes.  \nAbstract citation ID: igaf122.2665  \nASSOCIATION BETWEEN MULTIDIMENSIONAL  \nENVIRONMENTAL ENRICHMENT DOMAINS AND  \nINTRINSIC CAPACITY AMONG OLDER ADULTS  \nGuanzhou Wang, and Minqing Zhang, Duke University, Durham, North Carolina, United States  \nEnvironmental enrichment (EE), extensively studied in animal models, integrates cognitive, physical, and social stimulation to enhance functional health, but its translation to human aging research remains limited. Intrinsic capacity (IC), defined by the World Health Organization (WHO), provides a holistic framework for assessing functional health essential for independence in older age. This study examined associations and interactions between EE domains and IC among older adults. Using cross-sectional data from 5,454 older adults in the English Longitudinal Study of Ageing (ELSA), EE domains were assessed through self-reported physical activity (high/low), cognitive engagement (frequency of stimulating activities), and social  \nengagement (frequency of social and community interactions) .  \nIC was classified into high, medium, or low based on WHO’s Integrated Care for Older People (ICOPE) guidelines. Ordinal logistic regressions, adjusted for age, sex, education, smoking, and alcohol use, were performed. Results indicated significant independent associations between each EE domain and higher IC levels: physical activity (OR = 1.35, 95% CI = 1.17–1.56, p\u003C.001), cognitive engagement (OR = 1.21, 95% CI = 1.12–1.30, p\u003C.001), and social engagement (OR = 1.07, 95% CI = 1.02–1.11, p=.002).A significant interaction between cognitive engagement and physical activity (OR = 0.77, 95% CI = 0.66–0.89, p\u003C.001) indicated combined influences distinct from their individual","cbCaiurFoDfSRoMW","https://ap.wps.com/l/cbCaiurFoDfSRoMW","pdf",707414,"English","# Abstract\n## Study rationale: EE and intrinsic capacity\n## Methods: ELSA data and variable definitions\n## Results: independent associations and interactions\n## Implications and need for future trials","[{\"question\":\"What is intrinsic capacity in this study?\",\"answer\":\"Intrinsic capacity (IC) is defined using World Health Organization (WHO) guidance as a holistic framework for assessing functional health that supports independence in older age.\"},{\"question\":\"How were environmental enrichment domains measured?\",\"answer\":\"EE domains were assessed via self-reported physical activity level (high/low), frequency of stimulating cognitive activities, and frequency of social/community interactions.\"},{\"question\":\"What did the study find about the relationship between EE and IC?\",\"answer\":\"Each EE domain showed significant independent associations with higher IC levels, and an interaction between cognitive engagement and physical activity indicated combined effects beyond individual contributions.\"}]","ASSOCIATION BETWEEN MULTIDIMENSIONAL ENVIRONMENTAL ENRICHMENT DOMAINS AND INTRINSIC CAPACITY AMONG OLDER ADULTS | PDF",1790644616]