[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-442166-105":3,"detail-sidebar-cat-0-en-105":81,"doc-detail-442166-en":130},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":74,"head_meta":76,"extra_data":78,"updated_unix":80},105,"en","association-between-isolation-room-admission-in-intensive-care-units-and-long-term-psychiatric-disorders-a-nationwide-cohort-study","Association between isolation room admission in intensive care units and long-term psychiatric disorders - a nationwide cohort study","","ICU single-bed isolation room admission and its relationship to later psychiatric morbidity remains unclear. A nationwide retrospective cohort study used South Korea’s National Health Insurance Service data to follow adult ICU patients admitted between 2020 and 2022. New-onset depression, anxiety disorder, or PTSD within one year after ICU admission were assessed. Among 517,917 survivors, 26.3% developed a disorder; isolation admission showed a modest association, mainly depression, with small effects per isolation day.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/association-between-isolation-room-admission-in-intensive-care-units-and-long-term-psychiatric-disorders-a-nationwide-cohort-study/442166/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/association-between-isolation-room-admission-in-intensive-care-units-and-long-term-psychiatric-disorders-a-nationwide-cohort-study/442166.png","ImageObject",300,407,{"name":42,"@type":43},"Grenda","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-11-03","2026-09-29",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",9,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"What was the main research question of the study?","Question",{"text":63,"@type":64},"Whether admission to a single-bed ICU isolation room is associated with new-onset psychiatric disorders among ICU survivors.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"What psychiatric outcomes were measured after discharge?",{"text":68,"@type":64},"New diagnoses of depression, anxiety disorder, or post-traumatic stress disorder (PTSD) within one year after ICU admission.",{"name":70,"@type":61,"acceptedAnswer":71},"What did the study find about isolation-room admission and depression?",{"text":72,"@type":64},"ICU isolation-room admission was modestly associated with any psychiatric disorder, primarily driven by depression, and the association increased slightly with each additional isolation day.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},442166,1791092748,{"code":4,"msg":82,"data":83},"success",[84,88,92,96,101,106,110,115,119,122,126],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":85,"show_sort_weight":86,"slug":87},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":89,"show_sort_weight":90,"slug":91},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":93,"show_sort_weight":94,"slug":95},"Exam",70,"exam",{"id":97,"doc_module":4,"doc_module_name":25,"category_name":98,"show_sort_weight":99,"slug":100},5,"Comic",60,"comic",{"id":102,"doc_module":4,"doc_module_name":25,"category_name":103,"show_sort_weight":104,"slug":105},6,"Technology",50,"technology",{"id":107,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":108,"slug":109},7,40,"healthcare",{"id":111,"doc_module":4,"doc_module_name":25,"category_name":112,"show_sort_weight":113,"slug":114},8,"Research & Report",30,"research-report",{"id":55,"doc_module":4,"doc_module_name":25,"category_name":116,"show_sort_weight":117,"slug":118},"Religion & Spirituality",20,"religion-spirituality",{"id":117,"doc_module":4,"doc_module_name":25,"category_name":120,"show_sort_weight":117,"slug":121},"World Cup","world-cup",{"id":123,"doc_module":4,"doc_module_name":25,"category_name":124,"show_sort_weight":123,"slug":125},10,"Lifestyle","lifestyle",{"id":127,"doc_module":4,"doc_module_name":25,"category_name":128,"show_sort_weight":97,"slug":129},19,"General","general",{"code":4,"msg":82,"data":131},{"doc_id":79,"user_id":132,"nickname":42,"user_avatar":133,"doc_module":4,"category_id":107,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":139,"language":140,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":12,"update_tm":144,"read_time":145,"preview_page_count":4},7971474921005,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","Song et al. Critical Care (2026) 30:5 Critical Care  \n[https://doi.org/10.1186/s13054-025-05770-4](https://doi.org/10.1186/s13054-025-05770-4)  \nRESEARCH Open Access  \nAssociation between isolation room admission in intensive care units and longterm psychiatric disorders: a nationwide cohort study  \nIn-Ae Song 1,2, Hye Yoon Park3 and Tak Kyu Oh 1,2*  \nAbstract  \nBackground Whether admission to a single-bed intensive care unit (ICU) isolation room is associated with subsequent psychiatric morbidity remains uncertain. We investigated the association between ICU isolation and newonset psychiatric disorders after discharge.  \nMethods Using South Korea’s National Health Insurance Service database, we conducted a nationwide retrospective cohort study including adults admitted to any ICU between Jan 1 2020 and Dec 31 2022. We excluded patients \u003C 18 years, those who died within 1 year, and those with psychiatric diagnoses in the preceding 12 months. Outcomes were new diagnoses of depression, anxiety disorder, or post-traumatic stress disorder (PTSD) within 1 year after ICU admission. Exposure was any stay in a single-bed ICU isolation room; isolation duration (days) was also analyzed. Results Among 517 917 ICU survivors, 136 172 (26 . 3%) developed a psychiatric disorder within 1 year (depression 15. 6%, anxiety 16. 8%, PTSD 0 . 1%) . Admission to an ICU isolation room was modestly associated with any psychiatric disorder (odds ratio [OR], 1. 03; 95% confidence interval [CI], 1.01–1. 06; P = 0 . 034) . This association was primarily driven by depression (OR, 1. 06; 95% CI, 1.03–1. 10; P \u003C 0. 001) . There were no significant associations with anxiety disorder (P = 0 . 64) or PTSD (P = 0 . 307) . When treating the duration of ICU isolation as a continuous variable, each additional day of isolation showed a small incremental association with psychiatric disorder (OR per day, 1. 01; 95% CI, 1.01–1. 01; P \u003C 0. 001) and depression (OR, 1. 01; 95% CI, 1.01–1. 02; P \u003C 0. 001) .  \nConclusions ICU admission to a single-bed isolation room showed a small yet consistent association with post-ICU psychiatric morbidity, mainly depression. Given the minimal absolute difference and observational design, causality cannot be inferred. Nevertheless, isolation represents a potentially modifiable environmental exposure that warrants further confirmatory and mechanistic research, as well as pragmatic evaluation of mitigation strategies such as improved communication, family engagement, and circadian cueing.  \n*Correspondence: Tak Kyu Oh[airohtak@hotmail.com](airohtak@hotmail.com)  \nFull list of author information is available at the end of the article  \n© The Author(s) 2025. Open Access This article is licensed under a Creative Commons Attribution-NonCommercial-NoDerivatives 4.0 International License, which permits any non-commercial use, sharing, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if you modified the licensed material. You do not have permission under this licence to share adapted material derived from this article or parts of it. The images or other third party material in this article are included in the article’s Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit [http://creati](http://creati)[vecommons.org/l](vecommons.org/l)icenses/by-nc-nd/4.0/.  \nKey points  \n• Question: Is admission to a single-bed ICU isolation room associated with new-onset psychiatric disorders among ICU survivors?  \n• Findings: In a nationwide cohort of 517,917 survivors, 26. 3% developed a psychiatric disorder withi","cbCaibgQ1fVZbVxf","https://ap.wps.com/l/cbCaibgQ1fVZbVxf","pdf",1433322,11,"English","# Abstract\n## Background\n## Methods\n## Results\n## Conclusions\n# Key points\n## Question\n## Findings\n## Meaning\n# Keywords\n# Background\n## Psychiatric sequelae after ICU\n## Risk factors and need for environmental exposure research","[{\"question\":\"What was the main research question of the study?\",\"answer\":\"Whether admission to a single-bed ICU isolation room is associated with new-onset psychiatric disorders among ICU survivors.\"},{\"question\":\"What psychiatric outcomes were measured after discharge?\",\"answer\":\"New diagnoses of depression, anxiety disorder, or post-traumatic stress disorder (PTSD) within one year after ICU admission.\"},{\"question\":\"What did the study find about isolation-room admission and depression?\",\"answer\":\"ICU isolation-room admission was modestly associated with any psychiatric disorder, primarily driven by depression, and the association increased slightly with each additional isolation day.\"}]","Association between isolation room admission in intensive care units and long-term psychiatric disorders - a nationwide cohort study | PDF",1790699261,28]