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This prospective cohort study evaluated dosimetric impacts of a 1.5 T magnetic field using MR-linac in 100 esophageal cancer patients. Multiple plan phases were compared for dose-volume changes in organs at risk and targets using Monaco.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":40,"@type":76,"position":81},"https://docshare.wps.com/document/research-report/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/assessing-the-impact-of-a-15-t-transverse-magnetic-field-in-radiotherapy-for-esophageal-cancer-patients/331801/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/assessing-the-impact-of-a-15-t-transverse-magnetic-field-in-radiotherapy-for-esophageal-cancer-patients/331801.png","ImageObject",300,407,{"name":92,"@type":93},"Jiven","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-06","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What was the purpose of the study?","Question",{"text":113,"@type":114},"To assess the dosimetric impact of a 1.5 T magnetic field in esophageal cancer radiotherapy using MR-linac, and to evaluate implications for adaptation and personalized medicine.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How were the radiotherapy plans and comparisons performed?",{"text":118,"@type":114},"Plans were generated on 3DCT with adjustments across different phases, producing five plan types per patient. Dose-volume parameters for organs at risk and the target region were compared using Monaco.",{"name":120,"@type":111,"acceptedAnswer":121},"What key dosimetric findings were reported?",{"text":122,"@type":114},"Slight dose distortions appeared at air-tissue interfaces under the magnetic field, with some patients showing higher dose at tissue interfaces and a drop in clinical target volume coverage versus reference plans.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},331801,1790172749,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":39,"category_name":40,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":44,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},1099513958607,"https://ap-avatar.wpscdn.com/avatar/100002390cf8733938c?x-image-process=image/resize,m_fixed,w_180,h_180&k=1778829742770036399","Assessing the Impact of a 1.5 T Transverse Magnetic Field in Radiotherapy for Esophageal Cancer Patients  \nYukun Li, MS, Baosheng Li, PhD, Jian Zhu, PhD, Yong Yin, PhD, and Zhenjiang Li, PhD   \nTechnology in Cancer Research & Treatment  \nVolume 23: 1-9  \n© The Author(s) 2024  \nArticle reuse guidelines: [sagepub.com/journals-permissions](sagepub.com/journals-permissions)[ ](sagepub.com/journals-permissions)[DOI: 10.1177/15330338241227291](DOI: 10.1177/15330338241227291)[ ](DOI: 10.1177/15330338241227291)[journals.sagepub.com/home/tct](journals.sagepub.com/home/tct)  \nAbstract  \nPurpose: Magnetic resonance (MR)-guided radiotherapy enables visualization of static anatomy, capturing tumor motion, and extracting quantitative image features for treatment verification and outcome monitoring. However, magnetic fields in online MR imaging (MRI) require efforts to ensure accurate dose measurements. This study aimed to assess the dosimetric impact of a 1.5 T magnetic field in esophageal cancer radiotherapy using MR-linac, exploring treatment adaptation potential and personalized medicine benefits. Methods: A prospective cohort study enrolled 100 esophageal squamous cell carcinoma patients undergoing 4DCT and 3DCT scans before radiotherapy. The heart was contoured on 3DCT, 4DCT end expiration (EE), and 4DCTend inhalation (EI) images by the same radiation oncologist. Reference RT plans were designed on 3DCT, with adjustments for different phases generating 5 plan types per patient. Variations in dose-volume parameters for organs at risk and the target area among different plans were compared using Monaco 5.40.04. Results: Slight dose distortions at air-tissue interfaces were observed in the magnetic field’s presence. Dose at air-tissue interfaces (chest wall and heart wall) was slightly higher in some patients (3.0% tissue increased by 4.3 Gy on average) compared to nonmagnetic conditions. Average clinical target volume coverage V100 dropped from 99% to 95% compared to reference plans (planEI and planEE). Dose-volume histogram variation between the original plan and reference plans was within 2.3%. Superior–inferior (SI) direction displacement was significantly larger than lateral and anterior–posterior directions (P \u003C .05). Conclusion: Significant SI direction shift in lower esophageal cancerous regions during RT indicates the magnetic field’s dosimetric impact, including the electron return effect at tissue-air boundaries. Changes in OAR dose could serve as valuable indicators of organ impairment and target dose alterations, especially for cardiac tissue when using the 1.5 T linac method. Reoptimizing the plan with the magnetic field enhances the feasibility of achieving a clinically acceptable treatment plan for esophageal cancer patients.  \nKeywords  \nMR guided radiotherapy, esophageal cancer, electron return effect  \nAbbreviations  \nMR guided radiotherapy; EC, Esophageal cancer; ERE, Electron return effect; AR, adaptive radiotherapy.  \nReceived: August 7, 2023; Revised: December 11, 2023; Accepted: December 26, 2023.  \nIntroduction  \nCompared to other conventional medical imaging modalities, such as computed tomography (CT), cone beam CT, and ultrasound images, 1–3 magnetic resonance imaging (MRI) offers superior soft tissue contrast, providing a clearer visualization of both tumors and organs at risk (OARs) . MRI encompasses various parameters that reflect diverse tumor characteristics, including tissue oxygenation, cell density, and cell function features. Notably, MRI employs non-ionizing radiation, enabling  \n1 Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, Jinan City, China  \nCorresponding Author:  \nZhenjiang Li, Department of Radiation Oncology Physics and Technology, Shandong Cancer Hospital and Institute, Shandong First Medical University and Shandong Academy of Medical Sciences, No.440 Jiyan road, Huaiyin distri","cbCaiqzGIDay7kUW","https://ap.wps.com/l/cbCaiqzGIDay7kUW","pdf",978717,"English","# Abstract\n## Purpose\n## Methods\n## Results\n## Conclusion\n# Introduction","[{\"question\":\"What was the purpose of the study?\",\"answer\":\"To assess the dosimetric impact of a 1.5 T magnetic field in esophageal cancer radiotherapy using MR-linac, and to evaluate implications for adaptation and personalized medicine.\"},{\"question\":\"How were the radiotherapy plans and comparisons performed?\",\"answer\":\"Plans were generated on 3DCT with adjustments across different phases, producing five plan types per patient. Dose-volume parameters for organs at risk and the target region were compared using Monaco.\"},{\"question\":\"What key dosimetric findings were reported?\",\"answer\":\"Slight dose distortions appeared at air-tissue interfaces under the magnetic field, with some patients showing higher dose at tissue interfaces and a drop in clinical target volume coverage versus reference plans.\"}]","Assessing the Impact of a 1.5 T Transverse Magnetic Field in Radiotherapy for Esophageal Cancer Patients | PDF",1789995219,23]