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The work provides an overview of studying cancer in non-model organisms and reviews available detection, measurement, and quantification methods.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/research-report/","Research & Report",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/approaches-and-methods-to-study-wildlife-cancer/332955/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/approaches-and-methods-to-study-wildlife-cancer/332955.png","ImageObject",300,407,{"name":42,"@type":43},"Aurelia","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-10-30","2026-09-21",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",9,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"What motivates studying cancer in wildlife?","Question",{"text":63,"@type":64},"Field ecologists and evolutionary biologists have shown increasing interest in wildlife neoplasia, and this aligns with a One Health Approach that connects people, animals, and changing environments.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"What are the main methodological limitations in this field?",{"text":68,"@type":64},"The document highlights constraints in detecting cancer using non-invasive sampling, which limits progress in wildlife studies.",{"name":70,"@type":61,"acceptedAnswer":71},"Why is choosing a unique model species difficult?",{"text":72,"@type":64},"Suspected differential susceptibility and resistance among species can make it hard for field biologists to justify a single model species.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},332955,1791519117,{"code":4,"msg":82,"data":83},"success",[84,88,92,96,101,106,111,115,119,122,126],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":85,"show_sort_weight":86,"slug":87},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":89,"show_sort_weight":90,"slug":91},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":93,"show_sort_weight":94,"slug":95},"Exam",70,"exam",{"id":97,"doc_module":4,"doc_module_name":25,"category_name":98,"show_sort_weight":99,"slug":100},5,"Comic",60,"comic",{"id":102,"doc_module":4,"doc_module_name":25,"category_name":103,"show_sort_weight":104,"slug":105},6,"Technology",50,"technology",{"id":107,"doc_module":4,"doc_module_name":25,"category_name":108,"show_sort_weight":109,"slug":110},7,"Healthcare",40,"healthcare",{"id":112,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":113,"slug":114},8,30,"research-report",{"id":55,"doc_module":4,"doc_module_name":25,"category_name":116,"show_sort_weight":117,"slug":118},"Religion & Spirituality",20,"religion-spirituality",{"id":117,"doc_module":4,"doc_module_name":25,"category_name":120,"show_sort_weight":117,"slug":121},"World Cup","world-cup",{"id":123,"doc_module":4,"doc_module_name":25,"category_name":124,"show_sort_weight":123,"slug":125},10,"Lifestyle","lifestyle",{"id":127,"doc_module":4,"doc_module_name":25,"category_name":128,"show_sort_weight":97,"slug":129},19,"General","general",{"code":4,"msg":82,"data":131},{"doc_id":79,"user_id":132,"nickname":42,"user_avatar":133,"doc_module":4,"category_id":112,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":139,"language":140,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":12,"update_tm":144,"read_time":145,"preview_page_count":4},1099514068365,"https://ap-avatar.wpscdn.com/avatar/10000253d8d9f28188e?x-image-process=image/resize,m_fixed,w_180,h_180&k=1794309523707217728","Author Manuscr ipt Author Manuscr ipt Author Manuscr ipt Author Manuscript  \n\n| | HHS Public Access\u003Cbr>Author manuscript\u003Cbr>J Anim Ecol. Author manuscript; available in PMC 2025 January 20. |\n| --- | --- |\n\nPublished in final edited form as:  \nJ Anim Ecol. 2024 October ; 93(10): 1410–1428. doi:10.1111/1365-2656.14144 .  \nApproaches and methods to study wildlife cancer  \nMathieu Giraudeau 1 , Orsolya Vincze 1,2,3,4 , Sophie M. Dupont 1,5 , Tuul Sepp6 , Ciara Baines7 , Jean-Francois Lemaitre8 , Karin Lemberger9 , Sophie Gentès 1 , Amy Boddy 10 , Antoine M. Dujon 11,12 , Georgina Bramwell 11 , Valerie Harris 13 , Beata Ujvari 11,14 , Catherine Alix-Panabières 15 , Stephane Lair16 , David Sayag 17 , Dalia A. Conde 18,19 , Fernando Colchero 19,20,21 , Tara M. Harrison22 , Samuel Pavard23 , Benjamin Padilla-Morales24 , Damien Chevallier5 , Rodrigo Hamede 14,25 , Benjamin Roche 12,26,27 , Tamas Malkocs 1,28 , Athena  \nC. Aktipis 13,29 , Carlo Maley 13 , James DeGregori30 , Guillaume Le Loc’h31 , Frédéric Thomas 12,26  \n1Littoral Environnement et Sociétés (LIENSs), UMR 7266 CNRS-La Rochelle Université, La Rochelle, France  \n2 ImmunoConcEpT, CNRS UMR 5164, University of Bordeaux, Bordeaux, France  \n3 Hungarian Department of Biology and Ecology, Evolutionary Ecology Group, Babeş-Bolyai University, Cluj-Napoca, Romania  \n4 HUN-REN-DE Conservation Biology Research Group, Debrecen, Hungary  \n5Laboratoire de Biologie des ORganismes et Ecosystèmes Aquatiques (BOREA), FRE 2030, Muséum National d’Histoire Naturelle, CNRS, IRD, Sorbonne Université, Université de Caen Normandie, Université des Antilles, Paris, France  \n6 Institute of Ecology and Earth Sciences, University of Tartu, Tartu, Estonia  \n7 Department of Biological Sciences, University of Leeds, Leeds, United Kingdom  \n8Laboratoire de Biométrie et Biologie Évolutive, CNRS, UMR5558, Université Lyon 1, Villeurbanne, France  \n9Vet Diagnostics, Lyon, France  \n10 Department of Anthropology, University of California Santa Barbara, Santa Barbara, California, USA  \n11School of Life and Environmental Sciences, Deakin University, Waurn Ponds, Victoria, Australia  \n12CREEC/CANECEV, MIVEGEC, Unité Mixte de Recherches, IRD 224–CNRS5290–Université de Montpellier, Montpellier, France  \nThis is an open access article under the terms of the Creative Commons Attribution License, which permits use, distribution and reproduction in any medium, provided the original work is properly cited.  \nCorrespondence: Mathieu Giraudeau, [giraudeau.mathieu@gmail.com](giraudeau.mathieu@gmail.com).  \nMathieu Giraudeau and Orsolya Vincze contributed equally.  \nAUTHOR CONTRIBUTIONS  \nMG conceived the ideas of the manuscript, designed its structure and led the writing. All authors contributed to the writing of the manuscript.  \nCONFLICT OF INTEREST STATEMENT No conflict of interest to declare.  \nAuthor Manuscr ipt Author Manuscr ipt Author Manuscr ipt Author Manuscript  \nGiraudeau et al. Page 2  \n13Arizona Cancer Evolution Center, Biodesign Institute, Arizona State University, Tempe, Arizona, USA  \n14Centre de Recherches Ecologiques et Evolutives sur le Cancer, Montpellier, France;  \n15Laboratory of Rare Human Circulating Cells (LCCRH), University Medical Centre of Montpellier, Montpellier, France  \n16 Faculté de médecine vétérinaire, Canadian Wildlife Health Cooperative/Centre québécois sur lasanté des animaux sauvages, Université de Montréal, Saint-Hyacinthe, Quebec, Canada  \n17ONCOnseil—Unité d’expertise en oncologie vétérinaire, Toulouse, France  \n18 Department of Biology, University of Southern Denmark, Odense M, Denmark  \n19 Interdisciplinary Centre on Population Dynamics, University of Southern Denmark, Odense M, Denmark  \n20 Department of Primate Behavior and Evolution, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany  \n21 Department of Mathematics and Computer Sciences, University of Southern Denmark, Odense M, Denmark  \n22 Department of Clinical Sciences, College of Veterinary Medicine, North ","cbCaiu18knOMj0Ol","https://ap.wps.com/l/cbCaiu18knOMj0Ol","pdf",507263,33,"English","# Abstract\n## Background and motivation\n## Methodological constraints\n## Model-species selection challenges\n## Scope and reviewed approaches","[{\"question\":\"What motivates studying cancer in wildlife?\",\"answer\":\"Field ecologists and evolutionary biologists have shown increasing interest in wildlife neoplasia, and this aligns with a One Health Approach that connects people, animals, and changing environments.\"},{\"question\":\"What are the main methodological limitations in this field?\",\"answer\":\"The document highlights constraints in detecting cancer using non-invasive sampling, which limits progress in wildlife studies.\"},{\"question\":\"Why is choosing a unique model species difficult?\",\"answer\":\"Suspected differential susceptibility and resistance among species can make it hard for field biologists to justify a single model species.\"}]","Approaches and methods to study wildlife cancer | PDF",1790000120,83]