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The activities also include analyzing how loss of cell-cycle control contributes to cancer and examining meiosis with crossing over in Sordaria. The module provides experiment components, requirements, background concepts of the cell cycle and interphase, investigation procedures, study questions, results analysis, and safety/distribution notes for educational use.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/ap07-cell-division-mitosis-and-meiosis/457234/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/ap07-cell-division-mitosis-and-meiosis/457234.png","ImageObject",300,407,{"name":92,"@type":93},"SundayMiles","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",13,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What is the main goal of this experiment on cell division?","Question",{"text":113,"@type":114},"Students identify and differentiate stages of mitosis and meiosis. Onion root tips are stained to visualize mitotic stages and measure their durations.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How does the lab connect cell division to cancer?",{"text":118,"@type":114},"Students analyze mechanisms involving loss of cell-cycle control in cancer as part of Investigation III.",{"name":120,"@type":111,"acceptedAnswer":121},"Which organism is used to study meiosis and crossing over?",{"text":122,"@type":114},"The lab examines meiosis and crossing over in Sordaria (Sordaria fimicola), using provided Sordaria pictures for analysis.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},457234,1791168799,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":140,"language":141,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":142,"faqs":143,"seo_title":144,"seo_description":67,"update_tm":145,"read_time":146,"preview_page_count":4},1099529839202,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","BIG IDEA73  \nEDVO-Kit: AP07  \nCell Division:  \nMitosis and Meiosis  \nSee Page 3 for storage instructions.  \nEXPERIMENT OBJECTIVE:  \nThe objective of this experiment is for students to identify and differentiate various stages in mitosis and meiosis. Onion root tips are stained to identify the various stages and duration of mitosis. Students will also have an opportusnity to analyze mechanism involved with loss of cell cycle control in cancer. Meiosis and Crossing Over in Sordaria is also examined in this experiment.  \nEVTAP07.121213  \nEXPERIMENT  \nAP07 Cell Division: Mitosis and Meiosis  \nTable of Contents  \nPage  \nExperiment Components 3  \nExperiment Requirements 3  \nBackground Information 4  \nExperiment Procedures  \nExperiment Overview 12  \nInvestigations I & IV: Modeling Mitosis and Meiosis 13  \nInvestigation II: Studying the Effects of Environment on Mitosis 17  \nInvestigation III: Loss of Cell Cycle Control in Cancer 19  \nInvestigation V: Meiosis and Crossing Over in Sordaria 22  \nStudy Questions 23  \nInstructor’s Guidelines  \nNotes to the Instructor 25  \nPre-Lab Preparations 26  \nExperiment Results and Analysis 28  \nStudy Questions and Answers 32  \nMaterial Safety Data Sheets 34  \nThe Advanced Placement (AP) Program is a registered trademark of the College Entrance Examination Board. These laboratory materials have been prepared by EDVOTEK, Inc. which bears sole responsibility for their contents.  \nAll components are intended for educational research only. They are not to be used for diagnostic or drug purposes, nor administered to or consumed by humans or animals.  \nTHIS EXPERIMENT DOES NOT CONTAIN HUMAN DNA. None of the experiment components are derived from human sources.  \nEDVOTEK and The Biotechnology Education Company are registered trademarks of EDVOTEK, Inc.  \nThe Biotechnology Education Company® • 1-800-EDVOTEK • [www.edvotek.com](www.edvotek.com)  \nDuplication of any part of this document is permitted for non-proﬁt educational purposes only. Copyright © 1989-2012 EDVOTEK, Inc., all rights reserved. EVT AP07.121213  \n EXPERIMENT  \nCell Division: Mitosis and Meiosis AP07  \nExperiment Components  \nInvestigations I & IV  \n• 3-cm long Pipe cleaners (in 2 colors)  \n• Beads  \n• Small plastic bags  \nInvestigations II  \n• Carbol-fuschin (Ziehl-Neelson) stain  \n• Lectin (phytohemagglutinin PHA-M from Phaseolus vulgaris)  \n• Microscope slides and covers  \n• 10 plastic cups (to grow onion root tips)  \n• Sand  \n• 50 ml conical tubes  \nInvestigations III  \n• Karyotype pictures of normal individuals  \n• Karyotype pictures of patients 1, 2, and 3  \nInvestigations V  \n• Pictures of Sordaria ﬁmicola (Color pictures recommended)  \nStore the entire experiment at room temperature.  \nThis experiment is designed for 10 lab groups.  \nRequirements  \nInvestigations I & IV  \n• Colored pencils (2 colors)  \nInvestigation II  \n• Microscope  \n• 10 green onions (or scallions) with roots  \n• Ethanol  \n• Glacial acetic acid (12 M)  \n• Hydrochloric acid  \n• Razor blades  \n• Scissors  \n• Scientiﬁc cleaning wipes (Kimwipes)  \n• Disposable gloves  \nInvestigations III & V  \n• Photocopier  \nThe Biotechnology Education Company® • 1-800-EDVOTEK • [www.edvotek.com](www.edvotek.com)  \nDuplication of any part of this document is permitted for non-proﬁt educational purposes only. Copyright © 1989-2012 EDVOTEK, Inc., all rights reserved. EVT AP07.121213  \nEXPERIMENT  \nAP07 Cell Division: Mitosis and Meiosis  \nBackground Information  \nMITOSIS AND MEIOSIS  \nThe growth and development of every organism depends on the precise replication of the genetic material during each cell division. It is remarkable when one considers that as individuals we have all arisen from the fertilization of a single egg with a single sperm. From this single cell we develop into unique individuals with highly differentiated tissue types. The instructions for the precise timing of development, growth and maturation are all contained within DNA, which is organized as nucleotides encod","cbCaiuIS1Z6xs8md","https://ap.wps.com/l/cbCaiuIS1Z6xs8md","pdf",2558915,33,"English","# Experiment Components\n## Investigations I & IV\n## Investigations II\n## Investigations III\n## Investigations V\n# Experiment Procedures\n## Experiment Overview\n## Investigation I & IV: Modeling Mitosis and Meiosis\n## Investigation II: Studying the Effects of Environment on Mitosis\n## Investigation III: Loss of Cell Cycle Control in Cancer\n## Investigation V: Meiosis and Crossing Over in Sordaria\n# Study Questions\n# Instructor’s Guidelines\n## Notes to the Instructor\n## Pre-Lab Preparations\n## Experiment Results and Analysis\n# Study Questions and Answers\n# Material Safety Data Sheets","[{\"question\":\"What is the main goal of this experiment on cell division?\",\"answer\":\"Students identify and differentiate stages of mitosis and meiosis. Onion root tips are stained to visualize mitotic stages and measure their durations.\"},{\"question\":\"How does the lab connect cell division to cancer?\",\"answer\":\"Students analyze mechanisms involving loss of cell-cycle control in cancer as part of Investigation III.\"},{\"question\":\"Which organism is used to study meiosis and crossing over?\",\"answer\":\"The lab examines meiosis and crossing over in Sordaria (Sordaria fimicola), using provided Sordaria pictures for analysis.\"}]","AP07 Cell Division - Mitosis and Meiosis | PDF",1790748671,83]