[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-27541-en":3,"doc-seo-27541-105":27,"detail-sidebar-cat-0-en-105":69},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"doc_content":15,"file_id":16,"file_url":17,"file_type":18,"file_size":19,"view_count":4,"is_deleted":4,"is_public":20,"is_downloadable":20,"audit_status":20,"page_count":20,"language":21,"language_code":22,"site_id":23,"html_lang":22,"table_of_contents":15,"faqs":15,"seo_title":24,"seo_description":14,"update_tm":25,"read_time":26},27541,549758146520,"Patrick","https://ap-avatar.wpscdn.com/avatar/80002397d8c0411e94?_k=1775819394049821470",7,"Healthcare","Antihypertensives Angiotensin Receptor Blockers","This document focuses on Angiotensin Receptor Blockers (ARBs), a class of antihypertensive medications. It details their mechanism of action, explaining how they block angiotensin II, leading to vasodilation and a decrease in blood pressure. The document outlines the primary reasons for prescribing ARBs, including the treatment of hypertension and heart failure, with specific monitoring instructions for patients. It emphasizes careful assessment for angioedema and fluid overload, and advises patients to rise slowly and avoid salt substitutes due to the risk of hyperkalemia. A comprehensive list of adverse effects is provided, categorized by physiological system (CNS, CV, EENT, Endo, GI, GU, F&E, MS, Misc), with specific mention of angioedema and fever. Contraindications and precautions are highlighted, particularly for patients with heart failure, volume depletion, bilateral renal artery stenosis, angioedema, and during pregnancy (2nd/3rd trimester) due to the risk of neonatal death. The document also details numerous drug interactions, including reduced hypotensive effects with NSAIDs, decreased ACE1 effects with Rifampin, increased hypersensitivity risk with Allopurinol, potential decreased digoxin levels, diminished loop diuretic effects, possible lithium toxicity, increased risk of hypoglycemia with hypoglycemics, and elevated potassium levels with potassium-sparing diuretics. Finally, a nursing mnemonic is provided: ARBs typically end in \"-TAN,\" and they are often used as an alternative to ACE inhibitors in African American populations or when ACE inhibitors cause intolerable side effects.","","cbCaisjNG58eq65X","https://ap.wps.com/l/cbCaisjNG58eq65X","pdf",600157,1,"English","en",105,"Antihypertensives Angiotensin Receptor Blockers | PDF",1778275522,3,{"code":4,"msg":28,"data":29},"ok",{"site_id":23,"language":22,"slug":30,"title":13,"keywords":15,"description":14,"schema_data":31,"social_meta":64,"head_meta":66,"extra_data":68,"updated_unix":25},"antihypertensives-angiotensin-receptor-blockers",{"@graph":32,"@context":63},[33,49],{"@type":34,"itemListElement":35},"BreadcrumbList",[36,40,44,46],{"item":37,"name":38,"@type":39,"position":20},"https://docshare.wps.com","Home","ListItem",{"item":41,"name":42,"@type":39,"position":43},"https://docshare.wps.com/document/","Document",2,{"item":45,"name":12,"@type":39,"position":26},"https://docshare.wps.com/document/healthcare/",{"item":47,"name":13,"@type":39,"position":48},"https://docshare.wps.com/document/antihypertensives-angiotensin-receptor-blockers/27541",4,{"url":47,"name":13,"@type":50,"author":51,"headline":13,"publisher":53,"fileFormat":56,"description":14,"dateModified":57,"datePublished":57,"encodingFormat":56,"isAccessibleForFree":58,"interactionStatistic":59},"DigitalDocument",{"name":9,"@type":52},"Person",{"url":37,"name":54,"@type":55},"DocShare","Organization","application/pdf","2026-05-08",true,{"@type":60,"interactionType":61,"userInteractionCount":4},"InteractionCounter",{"@type":62},"ViewAction","https://schema.org",{"og:url":47,"og:type":65,"og:title":13,"og:site_name":54,"og:description":14},"article",{"robots":67,"canonical":47},"index,follow",{"doc_id":7,"site_id":23},{"code":4,"msg":5,"data":70},[71,75,79,83,88,93,96,101,106,109,113],{"id":20,"doc_module":4,"doc_module_name":42,"category_name":72,"show_sort_weight":73,"slug":74},"Story & Novel",90,"story-novel",{"id":43,"doc_module":4,"doc_module_name":42,"category_name":76,"show_sort_weight":77,"slug":78},"Literature",80,"literature",{"id":48,"doc_module":4,"doc_module_name":42,"category_name":80,"show_sort_weight":81,"slug":82},"Exam",70,"exam",{"id":84,"doc_module":4,"doc_module_name":42,"category_name":85,"show_sort_weight":86,"slug":87},5,"Comic",60,"comic",{"id":89,"doc_module":4,"doc_module_name":42,"category_name":90,"show_sort_weight":91,"slug":92},6,"Technology",50,"technology",{"id":11,"doc_module":4,"doc_module_name":42,"category_name":12,"show_sort_weight":94,"slug":95},40,"healthcare",{"id":97,"doc_module":4,"doc_module_name":42,"category_name":98,"show_sort_weight":99,"slug":100},8,"Research & Report",30,"research-report",{"id":102,"doc_module":4,"doc_module_name":42,"category_name":103,"show_sort_weight":104,"slug":105},9,"Religion & Spirituality",20,"religion-spirituality",{"id":104,"doc_module":4,"doc_module_name":42,"category_name":107,"show_sort_weight":104,"slug":108},"World Cup","world-cup",{"id":110,"doc_module":4,"doc_module_name":42,"category_name":111,"show_sort_weight":110,"slug":112},10,"Lifestyle","lifestyle",{"id":114,"doc_module":4,"doc_module_name":42,"category_name":115,"show_sort_weight":84,"slug":116},19,"General","general"]