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Key side effects and important considerations for ondansetron, such as the risk of Serotonin Syndrome, are detailed, including symptoms like muscle rigidity, hypertension, tachycardia, and agitation. The document also mentions contraindications for Metoclopramide, such as a bleeding duodenal ulcer, and emphasizes the importance of reporting specific symptoms like lip smacking, puffing of cheeks, and blinking of eyes to a healthcare provider immediately, as these can be indicative of serious adverse reactions such as extrapyramidal symptoms or tardive dyskinesia. 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