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The case report describes a 57-year-old man with neck mass, hoarseness, and dysphagia. Imaging demonstrated cancer thrombus in bilateral internal jugular veins, and biopsy confirmed ATC. The report summarizes imaging and pathological characteristics, highlighting ultrasound’s value in assessing intravascular cancer thrombus for accurate diagnosis and management.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/anaplastic-thyroid-carcinoma-with-bilateral-internal-jugular-vein-tumour-thrombus-formation-a-case-report/371409/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/anaplastic-thyroid-carcinoma-with-bilateral-internal-jugular-vein-tumour-thrombus-formation-a-case-report/371409.png","ImageObject",300,407,{"name":92,"@type":93},"Margaret","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-23",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What clinical symptoms did the 57-year-old patient present with?","Question",{"text":112,"@type":113},"He presented with a rapidly enlarged anterior cervical mass, hoarseness, and difficulty swallowing.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What key imaging findings supported the diagnosis?",{"text":117,"@type":113},"Ultrasound showed abnormal thyroid morphology and internal jugular vein lumen filling with hypoechoic material that could not be fully deflated with probe pressure; color Doppler demonstrated abundant blood flow signals.",{"name":119,"@type":110,"acceptedAnswer":120},"How was the diagnosis confirmed and what was emphasized in the report?",{"text":121,"@type":113},"Ultrasound-guided coarse needle aspiration biopsy confirmed a malignant thyroid tumor consistent with ATC. The report emphasizes ultrasound’s role in evaluating intravascular cancer thrombus to aid accurate diagnosis and management.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},371409,1790816295,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":81,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":39},137451207643,"https://ap-avatar.wpscdn.com/davatar_3d24733baf745e90a7e4bdd5f77d97b2","Anaplastic thyroid carcinoma with bilateral internal jugular vein tumour thrombus formation: a case report  \nRuiqian Yan, MM1 , Junxi Gao, MD1,􀀃  \n1 Department of Ultrasound Diagnosis Abdomen, The First Affiliated Hospital of Xinjiang Medical University, Urumqi, Xinjiang 830011, China 􀀃 Corresponding author: Junxi Gao, MD, Department of Ultrasound Diagnosis Abdomen, The First Affiliated Hospital of Xinjiang Medical University, Beijing Road Street, Urumqi, Xinjiang 830011, China ([gjx-1974@163.com](gjx-1974@163.com))  \nAbstract  \nAnaplastic thyroid carcinoma (ATC) is a highly aggressive thyroid malignancy, comprising 1%-4% of thyroid cancers, with rapid local invasion and distant metastasis. We report a 57-year-old male with ATC presenting with a neck mass, hoarseness, and dysphagia. Imaging showed cancer thrombus in bilateral internal jugular veins, with a biopsy confirming ATC. This case highlights the imaging and pathological features of ATC and emphasizes the importance of ultrasound in evaluating intravascular cancer thrombus, aiding accurate diagnosis and management.  \nKeywords: interstitial thyroid carcinoma; conventional ultrasound; jugular vein cancer thrombus.  \nClinical presentation  \nA 57-year-old male patient, who found an anterior cervical mass 1 year ago, was admitted to our hospital 1 month ago because of a markedly enlarged anterior cervical mass accompanied by hoarseness and difficulty in swallowing.  \nImaging findings  \nUltrasound showed that the right lobe of the thyroid gland was about 4.2 cm thick, the left lobe was about 4.0 cm thick, and the isthmus was about 2.2 cm thick, with abnormal morphology; multiple strong echoes could be seen in the thyroid gland, some of which were in tiny clusters, some of them were in the shape of a ring, with no acoustic shadows at the back, and the rest of the thyroid gland tissues were hypoechoic; tortuous tubular hypoechoic echogenicity could be seen around the thyroid glands bilaterally, mainly in the isthmus, and the colour Doppler showed that hyperechogenicity could be seen in the form of point streaks of blood flow signals. The lumen of the internal jugular vein and its cervical branches was full of hypoechoic sound, and the lumen could not be completely deflated after probe pressure was applied, and the colour Doppler showed that the hypoechoic sound was richly distributed with blood flow signals (Figure 1) . Ultrasound-guided coarse needle aspiration biopsy suggested a malignant tumour of the thyroid gland. Enhanced CT showed that the volume of the thyroid gland increased significantly and the enhancement of bilateral lobes was uneven, ring-shaped, and nodular calcification foci could be seen in the thyroid gland, the trachea was narrowed by compression, and the lumen of bilateral jugular veins was not uniformly densely packed, with slightly low-density shadows, and nodular and irregularly shaped high-density shadows could be seen (Figure 2) .  \nTreatment, outcome, and follow-up  \nRadical thyroid cancer surgery was performed in the clinic. During the operation, the volume of the thyroid gland increased significantly, cystic and solid occupations were palpable in the thyroid gland, the tumour tissue invaded the surrounding muscles and blood vessels, and the blood vessels around the thyroid gland were thickened significantly. The tumour tissue pushed the internal jugular vein to cross and infiltrative growth to the vein. Under the microscope, the tumour tissue in the thyroid gland showed solid nest-like growth, with papillary structures in the local area, and the cell nuclei were easily seen (Figure 3) . Immunohistochemistry: cytokeratin (CK) (þ), thyroid transcription factor-1 (TTF-1) (þ), paired box gene (Pax-8) (þ), CD56 (þ), VIM (þ), Ki-67 (45%) . Clinical diagnosis: interstitial thyroid carcinoma with necrosis and intravascular cancerous thrombosis.  \nDiscussion  \nAnaplastic thyroid carcinoma (ATC) is a highly aggressive malignant tumour of the thyroid, accountin","cbCaickxGi4kIBlC","https://ap.wps.com/l/cbCaickxGi4kIBlC","pdf",789057,"English","# Abstract\n# Clinical presentation\n# Imaging findings\n# Treatment, outcome, and follow-up\n# Discussion","[{\"question\":\"What clinical symptoms did the 57-year-old patient present with?\",\"answer\":\"He presented with a rapidly enlarged anterior cervical mass, hoarseness, and difficulty swallowing.\"},{\"question\":\"What key imaging findings supported the diagnosis?\",\"answer\":\"Ultrasound showed abnormal thyroid morphology and internal jugular vein lumen filling with hypoechoic material that could not be fully deflated with probe pressure; color Doppler demonstrated abundant blood flow signals.\"},{\"question\":\"How was the diagnosis confirmed and what was emphasized in the report?\",\"answer\":\"Ultrasound-guided coarse needle aspiration biopsy confirmed a malignant thyroid tumor consistent with ATC. The report emphasizes ultrasound’s role in evaluating intravascular cancer thrombus to aid accurate diagnosis and management.\"}]","Anaplastic thyroid carcinoma with bilateral internal jugular vein tumour thrombus formation - a case report | PDF",1790192006]