[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-331315-105":59,"doc-detail-331315-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","an-unexpected-turn-an-unusual-case-of-a-metastatic-ovarian-carcinoma-arising-from-a-colorectal-malignancy","An Unexpected Turn - An Unusual Case of a Metastatic Ovarian Carcinoma Arising from a Colorectal Malignancy","","Krukenberg tumors are very rare, and their origin can be difficult to define when gross appearance mimics primary ovarian cancer. A 24-year-old Filipino woman presented with an enlarging abdominal mass and low back pain without clear gastrointestinal symptoms, leading initially to primary ovarian malignancy and genitourinary tuberculosis. Imaging and work-up supported malignant ovarian disease and multi-organ involvement, but surgery with histopathology confirmed metastatic mucinous adenocarcinoma of colonic origin. The case underscores diagnostic differentiation between benign and malignant ovarian lesions and between primary and metastatic ovarian neoplasms.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/an-unexpected-turn-an-unusual-case-of-a-metastatic-ovarian-carcinoma-arising-from-a-colorectal-malignancy/331315/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/an-unexpected-turn-an-unusual-case-of-a-metastatic-ovarian-carcinoma-arising-from-a-colorectal-malignancy/331315.png","ImageObject",300,407,{"name":92,"@type":93},"Miles","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-28","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why was the case initially suspected to be primary ovarian cancer or genitourinary tuberculosis?","Question",{"text":112,"@type":113},"The gross and radiologic findings showed bilateral ovarian new growth with non-benign features and associated lesions. The pattern also overlapped with tuberculosis, so early diagnoses included malignant ovarian disease and genitourinary tuberculosis.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What clinical symptoms and physical findings were reported?",{"text":117,"@type":113},"The patient had a 4-month history of low back pain and difficulty in ambulation, progressive abdominal enlargement, hypogastric pain, unintentional weight loss, and vomiting episodes. Exam revealed a palpable non-tender, immovable hypogastric mass about 8.0 x 11.0 cm.",{"name":119,"@type":110,"acceptedAnswer":120},"What confirmed the final diagnosis?",{"text":121,"@type":113},"Surgery was performed, and histopathology revealed metastatic mucinous adenocarcinoma of colonic origin rather than primary ovarian cancer.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},331315,1790089975,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":29,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144},13056703019404,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","CASE REPORT  \nAn Unexpected Turn: An Unusual Case of a Metastatic Ovarian Carcinoma Arising from a Colorectal Malignancy  \nPatricia Jarmin L. Pua, MD, Mary Nel B. Bacalso, MD and Mariaem M. Andres, MD  \nInstitute of Radiology, St. Luke’s Medical Center, Quezon City, Philippines  \nABSTRACT  \nKrukenberg tumors are very rare. Its origin is difficult to define especially if its gross features mimic a primary ovarian cancer. We present a case of a 24-year-old Filipino female patient with metastatic mucinous ovarian adenocarcinoma of colonic origin that mimicked primary ovarian cancer and genitourinary tuberculosis. Surgery was done and histopathology revealed that the cancer was a metastatic mucinous adenocarcinoma of colonic origin. This case highlights the importance of differentiating between benign and malignant ovarian lesions as well as distinction between primary and metastatic ovarian neoplasms. Radiological imaging has an evolving role in diagnosis of different cancers, which may be improved through better clinical correlation and developing meaningful differential diagnosis while advancing to a more strategized algorithm in the diagnostic approach.  \nKeywords: Krukenberg tumor, ovarian cancer, mucinous adenocarcinoma, ovarian metastasis, colorectal cancer  \nINTRODUCTION  \nOral Presentation – Philippine College of Radiology Annual National Interesting Case Competition, February 2021 via online platform.  \neISSN 2094-9278 (Online) Published: August 30, 2024  \n[https://doi.org/10.47895/amp.vi0.7969](https://doi.org/10.47895/amp.vi0.7969)  \n[Corresponding author: Patricia Jarmin L. Pua](Corresponding author: Patricia Jarmin L. Pua), MD Institute of Radiology  \nSt. Luke’s Medical Center  \n279 E. Rodriguez Sr. Ave., Quezon City 1112, Philippines  \nEmail: [patriciajarmin.pua@gmail.com](patriciajarmin.pua@gmail.com)  \nORCiD: [https://orcid.org/0000-0002-6306-3696](https://orcid.org/0000-0002-6306-3696)  \nKrukenberg tumors are metastatic ovarian neoplasms that contain mucin-secreting cells originating from the gastrointestinal tract, with majority originating from the stomach.1 Only 11% of Krukenberg tumors arise from the colon.2 Clinical presentation includes increasing abdominal girth and abdominal pain. In this case report, we have a 24-year-old patient with an unusual presentation of low back pain, difficulty in ambulation, and an enlarging abdominal mass without apparent gastrointestinal symptoms. Initial diagnoses were primary ovarian malignancy and genitourinary tuberculosis but eventually turned out to be metastatic mucinous ovarian carcinoma.  \nCASE REPORT  \nA 24-year-old Filipino female patient without comorbidities presented with a 4-month history of low back pain and difficulty in ambulation. Progressive abdominal enlargement with associated hypogastric pain, unintentional weight loss, and vomiting episodes were noted. However, there were no changes in bowel movement, fever, abnormal vaginal bleeding, or anorexia. Pertinent physical examination showed a palpable non-tender immovable hypogastric mass measuring approximately 8.0 x 11.0 cm (W x L). The patient previously had a history of pulmonary tuberculosis but completed treatment. There is also a family history of colon, ovarian, and breast cancer. Upon consult, abdominal ultrasound (US) (Figure 1) was done which  \nKrukenberg Tumor  \nshowed bilateral ovarian new growth with non-benign features, aortic lymphadenopathies, and liver nodules. Initial considerations were malignant bilateral ovarian new growth and abdominopelvic tuberculosis.  \nFurther work-up showed anemia (serum hemoglobin: 10.9 mg/dL; Normal range: 12 to 15 mg/dL), and elevated CA 19-9 (1653 U/mL; normal range \u003C37 U/m), CA 125 (49.60 U/mL; normal range \u003C35 U/mL) and Carcinoembryonic antigen (CEA) (377.50 ng/mL; normal range \u003C2.5ng/mL) .  \nContrast-enhanced Computed Tomography (CECT) scan of the abdomen showed an enlarged, lobulated, predominantly cystic pelvic mass (Figure 2) . The mass shows intralesion","cbCaigfRJsjxVICX","https://ap.wps.com/l/cbCaigfRJsjxVICX","pdf",3844470,"English","# Abstract\n# Introduction\n# Case report\n## Clinical presentation and initial assessment\n## Imaging findings\n## Laboratory results and tumor markers\n## Surgical and intraoperative findings\n## Histopathology and diagnostic conclusion","[{\"question\":\"Why was the case initially suspected to be primary ovarian cancer or genitourinary tuberculosis?\",\"answer\":\"The gross and radiologic findings showed bilateral ovarian new growth with non-benign features and associated lesions. The pattern also overlapped with tuberculosis, so early diagnoses included malignant ovarian disease and genitourinary tuberculosis.\"},{\"question\":\"What clinical symptoms and physical findings were reported?\",\"answer\":\"The patient had a 4-month history of low back pain and difficulty in ambulation, progressive abdominal enlargement, hypogastric pain, unintentional weight loss, and vomiting episodes. Exam revealed a palpable non-tender, immovable hypogastric mass about 8.0 x 11.0 cm.\"},{\"question\":\"What confirmed the final diagnosis?\",\"answer\":\"Surgery was performed, and histopathology revealed metastatic mucinous adenocarcinoma of colonic origin rather than primary ovarian cancer.\"}]","An Unexpected Turn - An Unusual Case of a Metastatic Ovarian Carcinoma Arising from a Colorectal Malignancy | PDF",1789992623,15]