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The emphasis on local phytotherapeutic options highlights the distinctive character of Djibouti’s flora and its phytoconstituents, proposed to counter carcinomas. This overview examines oncological risk factors, essential control prerequisites, and dietary habits, then reviews indigenous essential oil therapies and supports further 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Promising Endeavors in Local Essential Oil Treatment  \nFatouma Mohamed Abdoul-Latif 1, *, Ayoub Ainane 2, Ibrahim Houmed Aboubaker 3, Jalludin Mohamed 1 and Tarik Ainane 2  \nCitation: Abdoul-Latif, F.M.; Ainane, A.; Houmed Aboubaker, I.; Mohamed, J.; Ainane, T. An Overview of Cancer in Djibouti:  \nCurrent Status, Therapeutic Approaches, and Promising Endeavors in Local Essential Oil Treatment. Pharmaceuticals 2023, 16, 1617. [https://doi.org/10.3390/](https://doi.org/10.3390/)[ ](https://doi.org/10.3390/)ph16111617  \nAcademic Editor: Daniela De Vita  \nReceived: 7 October 2023  \nRevised: 24 October 2023  \nAccepted: 31 October 2023  \nPublished: 16 November 2023  \nCopyright: © 2023 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ([https://](https://)[ ](https://)[creativecommons.org/licenses/by/](creativecommons.org/licenses/by/)[ ](creativecommons.org/licenses/by/)[4.0/](4.0/)) .  \n1 Medicinal Research Institute, Center for Studies and Research of Djibouti, IRM-CERD, Route de l'A²roport, Haramous, Djibouti P.O. Box 486, Djibouti; [mohamed.jalludin@gmail.com](mohamed.jalludin@gmail.com)  \n2 Superior School of Technology of Khenifra (EST-Khenifra), University of Sultan Moulay Slimane, P.O. Box 170, Khenifra 54000, Morocco; [a.ainane@usms.ma](a.ainane@usms.ma) (A.A.); [t.ainane@usms.ma](t.ainane@usms.ma) (T.A.)  \n3 Peltier Hospital of Djibouti, Djibouti City P.O. Box 2123, Djibouti; [ibrahimhoumed@yahoo.fr](ibrahimhoumed@yahoo.fr)  \n* Correspondence: [fatoumaabdoulatif@gmail.com](fatoumaabdoulatif@gmail.com)  \nAbstract: Djibouti, a developing economy, grapples with significant socioeconomic obstacles and the prevalence of infectious pathologies, including certain forms of neoplasms. These challenges are exacerbated by limited access to affordable medical technologies for diagnosis, coupled with a lack of preventive interventions, particularly in disadvantaged areas. The attention devoted to local phytotherapeutic treatments underscores the uniqueness of Djibouti's flora, resulting from its distinctive geographical position. International focus specifically centers on harnessing this potential as a valuable resource, emphasizing the phytoconstituents used to counter pathologies, notably carcinomas. This comprehensive overview covers a broad spectrum, commencing with an examination of the current state of knowledge, namely an in-depth investigation of oncological risk factors. Essential elements of control are subsequently studied, highlighting the fundamental prerequisites for effective management. The significance of dietary habits in cancer prevention and support is explored in depth, while traditional methods are examined, highlighting the cultural significance of indigenous essential oil therapies and encouraging further research based on the promising results.  \nKeywords: cancer; Djibouti; essential oils; phytotherapy; status; treatment  \n1. Introduction  \nCancer remains a significant global cause of mortality, and though strides have been taken, substantial headway in curbing its impact has proven elusive [1] . The genesis of cancers can be attributed to a trio of factors: erroneous dietary habits, genetic predisposition, and environmental influences. Remarkably, up to 95% of cancer occurrences stem from lifestyle choices, with a latency period of 20 to 30 years before symptoms manifest [2] . Insights from reputable sources such as the American Cancer Society and the International Union Against Cancer indicate that an estimated 12 million cancer diagnoses and 7 million deaths occur globally—a figure anticipated to double by 2030 (projected at 27 million cases with 17 million deaths) [3] . The challenge of efficaciously eradicating cancer and comprehensively managing its progression looms l","cbCaiePnzi12R8dU","https://ap.wps.com/l/cbCaiePnzi12R8dU","pdf",2353383,24,"English","# Abstract\n# Introduction\n## Global cancer burden and lifestyle risk factors\n## Current pharmaceutical interventions and mechanisms\n## Natural products and phytotherapy for cancer prevention\n## Djibouti’s geographic context and local therapies","[{\"question\":\"What barriers worsen cancer management challenges in Djibouti?\",\"answer\":\"Limited access to affordable medical technologies for diagnosis and a lack of preventive interventions, particularly in disadvantaged areas, intensify the situation.\"},{\"question\":\"Which oncological risk factors does the overview emphasize?\",\"answer\":\"It highlights dietary habits, genetic predisposition, and environmental influences as key drivers of cancer development.\"},{\"question\":\"How does the document relate essential oils and phytotherapy to cancer treatment?\",\"answer\":\"It discusses Djibouti’s unique flora and phytoconstituents and reviews indigenous essential oil therapies, encouraging further research based on promising results.\"}]","An Overview of Cancer in Djibouti - Current Status, Therapeutic Approaches, and Promising Endeavors in Local Essential Oil Treatment | PDF",1790224866]