[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-439913-105":59,"doc-detail-439913-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","an-incidental-finding-of-duodenal-gastrointestinal-stromal-tumor-dgist-a-case-report","An incidental finding of duodenal gastrointestinal stromal tumor (dGIST): a case report","","Duodenal gastrointestinal stromal tumors (dGISTs) are rare mesenchymal tumors that are often discovered incidentally but typically present with longer-standing abdominal mass, bleeding, or obstruction. This case report describes an older male with only 10 days of fever and progressive abdominal swelling, initially lacking classic gastrointestinal bleeding, weight loss, or vomiting. Imaging suggested alternative diagnoses such as vascular or intestinal causes, delaying recognition. The patient underwent complete surgical management and recovered well with adjuvant imatinib therapy, supporting early consideration of dGIST for favorable outcomes.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/an-incidental-finding-of-duodenal-gastrointestinal-stromal-tumor-dgist-a-case-report/439913/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/an-incidental-finding-of-duodenal-gastrointestinal-stromal-tumor-dgist-a-case-report/439913.png","ImageObject",300,407,{"name":92,"@type":93},"Grenda","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why was the dGIST diagnosis delayed in this case?","Question",{"text":112,"@type":113},"The tumor presented with acute, nonspecific symptoms of fever and an abdominal mass, which is unusual for dGIST and can mimic other conditions.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the patient treated after diagnosis?",{"text":117,"@type":113},"The patient received complete surgical resection and recovered well on imatinib therapy after surgery.",{"name":119,"@type":110,"acceptedAnswer":120},"What does the case emphasize about evaluating short-duration abdominal symptoms?",{"text":121,"@type":113},"It highlights the importance of considering dGIST even when abdominal symptoms have been present for a short period, enabling earlier diagnosis and favorable outcomes.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},439913,1790916354,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},7971474921005,"https://ap-avatar.wpscdn.com/davatar_29158cc5080c5b710cf443261637dec0","Case Report  \nAn incidental finding of duodenal gastrointestinal stromal tumor (dGIST): a case report  \nAbsar Nazir, MBBS, FCPS, MRCS, Nadir Khurram Rehman, MBBS, MD*, Fizza Khalid, MBBS, Arishba Arshad, MBBS  \nIntroduction: Duodenal gastrointestinal stromal tumors (dGISTs) are rare mesenchymal tumors of the gastrointestinal tract, comprising only 4–5% of them. Usually they are presented with a longstanding history of an abdominal mass, blood in stools or obstruction symptoms. But in our case, the patient presented with a 10-day history offever along with an abdominal swelling and is recovering well on imatinib therapy after surgery.  \nCase Presentation: Here, we document a case of an unusual presentation of dGIST with a short history of fever and abdominal mass, which incidentally got diagnosed and treated with surgery and imatinib.  \nClinical Discussion: The presentation of dGIST with acute, nonspecific symptoms of fever and abdominal mass is unusual, which delays its diagnosis. Complete surgical resection with or without tyrosine kinase inhibitors remains the mainstay of curative treatment.  \nConclusion: This case signifies the importance of considering dGIST even in patients with a short history of abdominal symptoms. Early diagnosis and surgical management helps in achieving favorable outcomes.  \nKeywords: duodenum, gastrointestinal stromal tumor, imatinib, KIT  \nIntroduction  \nThe most common mesenchymal tumors of the gastrointestinal tract are the gastrointestinal stromal tumors (GISTs), among which duodenal stromal tumors are only 4–5%[1,2] . They are most commonly diagnosed in patients in their sixth decade of life[3] . Among duodenal ones, they usually involve the second and third parts of the duodenum[4] . Initially being asymptomatic, 5–40% have an incidental diagnosis[3] . Then, as their size increases, patients may complain of blood in stools, abdominal pain, abdominal mass, and intestinal obstruction[4] .  \nGISTs tend to arise from interstitial cells of Cajal, involving activating proto-oncogene for tyrosine kinase receptor (KIT) mutations (70%) followed by platelet-derived growth factor receptor alpha (PDGFRA) mutations (10–15%), leading to uncontrolled cellular proliferation[5,6] . Though CT is the first investigation sought for the GIST’s diagnosis, and its extent, the final diagnosis is based on histopathology, immunohistochemistry, and tumor marker detection[6] .  \nDepartment of Surgery, Sir Gangaram Hospital, Lahore, Pakistan  \nSponsorships or competing interests that may be relevant to content are disclosed at the end of this article.  \n*Corresponding author. Address: Department of Surgery, Sir Gangaram Hospital, Shara-I-Fatima Jinnah, Queen’s Road, Jinnah Town, Lahore 54000, Pakistan.  \nTel.: +[924299200572. E-mail: nadirrehman7@gmail.com](924299200572. E-mail: nadirrehman7@gmail.com) (N.K. Rehman). Copyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc. This isan open access article distributed under the Creative Commons Attribution License 4.0 (CCBY), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.  \nAnnals of Medicine & Surgery (2026) 88:866–870  \nReceived 29 August 2025; Accepted 13 November 2025  \nPublished online 25 November 2025  \n[http://dx.doi.org/10.1097/MS9.0000000000004404](http://dx.doi.org/10.1097/MS9.0000000000004404)  \nHIGHLIGHTS  \n● Gastrointestinal stromal tumor (GIST) is an overall rare, but the most common mesenchymal tumor of the Gastrointestinal Tract.  \n● Duodenal gastrointestinal stromal tumors (dGIST) account for only 4–5% of GISTs.  \n● dGIST usually presents as an abdominal mass, with symptoms of gastrointestinal bleeding such as melena or hematemesis and may also present with symptoms of obstruction and/or perforation.  \n● Here, we document a case presented with a short, 10-day history of nonspecific symptoms such as a newly presenting localized abdominal mass with fever which was incid","cbCaihDKuki1k6fb","https://ap.wps.com/l/cbCaihDKuki1k6fb","pdf",2522596,"English","# Introduction\n## Case Presentation\n## Clinical Discussion\n## Conclusion\n# Keywords","[{\"question\":\"Why was the dGIST diagnosis delayed in this case?\",\"answer\":\"The tumor presented with acute, nonspecific symptoms of fever and an abdominal mass, which is unusual for dGIST and can mimic other conditions.\"},{\"question\":\"How was the patient treated after diagnosis?\",\"answer\":\"The patient received complete surgical resection and recovered well on imatinib therapy after surgery.\"},{\"question\":\"What does the case emphasize about evaluating short-duration abdominal symptoms?\",\"answer\":\"It highlights the importance of considering dGIST even when abdominal symptoms have been present for a short period, enabling earlier diagnosis and favorable outcomes.\"}]","An incidental finding of duodenal gastrointestinal stromal tumor (dGIST): a case report | PDF",1790690520,13]