[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-458652-105":59,"doc-detail-458652-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","an-atypical-case-of-lactobacillus-jensenii-discitis-and-osteomyelitis","An Atypical Case of Lactobacillus jensenii Discitis and Osteomyelitis","","Lactobacillus species are generally considered beneficial and are not typically pathogenic in humans. Bloodstream and tissue infections are uncommon and usually occur in immunocompromised patients. This case report describes a 63-year-old woman with L. jensenii lumbosacral discitis and osteomyelitis, complicated by small bilateral psoas abscesses and myositis. L4-L5 biopsy confirmed L. jensenii by next-generation sequencing after negative conventional cultures. Piperacillin-tazobactam for six weeks was followed by amoxicillin-clavulanate, with symptom resolution and no concerning recurrence.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/an-atypical-case-of-lactobacillus-jensenii-discitis-and-osteomyelitis/458652/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/an-atypical-case-of-lactobacillus-jensenii-discitis-and-osteomyelitis/458652.png","ImageObject",300,407,{"name":92,"@type":93},"Mimi","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why was Lactobacillus jensenii considered unusual in this patient?","Question",{"text":112,"@type":113},"Lactobacillus species are generally considered beneficial and are not typically pathogenic, and bloodstream or tissue infections are uncommon. In this case, vertebral discitis and osteomyelitis developed despite negative conventional cultures.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How was the diagnosis of Lactobacillus jensenii confirmed?",{"text":117,"@type":113},"L4-L5 disc biopsy was positive for L. jensenii using next-generation sequencing. Conventional tissue cultures were negative, while inflammatory markers were elevated.",{"name":119,"@type":110,"acceptedAnswer":120},"What treatment was used and what was the outcome?",{"text":121,"@type":113},"The patient received piperacillin-tazobactam for six weeks, then transitioned to amoxicillin-clavulanate to complete an approximately two-month antimicrobial course. Gait instability and recurrent falls resolved satisfactorily, with no concerning recurrence after stopping antibiotics.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},458652,1790820883,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},2336477974920,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","Review began 11/20/2025  \nReview ended 12/04/2025  \nPublished 12/08/2025  \n© Copyright 2025  \nChiborise et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CCBY 4.0. , which permits unrestricted use , distribution , and reproduction in any medium , provided the original author and source are credited.  \nDOI: 10.7759/cureus.98774  \nOpen Access Case Report  \nAn Atypical Case of Lactobacillus jensenii Discitisand Osteomyelitis  \nTarisai D. Chiborise 1 , Tarvinder S. Gilotra 1  \n1. Infectious Diseases, Catholic Health, Kenmore, USA  \nCorresponding author: Tarisai D. Chiborise, [tarisaidennis@gmail.com](tarisaidennis@gmail.com)  \nAbstract  \nLactobacillus species are generally considered beneficial and are not typically pathogenic in humans. Bloodstream and tissue infections are uncommon and usually occur in immunocompromised patients. We present a case of a 63-year-old female with Lactobacillus jensenii lumbosacral discitis and osteomyelitis, complicated by small bilateral psoas abscesses and myositis. L4-L5 lumbar biopsy confirmed the presence of L. jensenii via next-generation sequencing after conventional tissue and blood cultures were negative. The presumed etiology of this infection was a genitourinary source. The patient received piperacillin-tazobactam for six weeks, followed by a transition to amoxicillin-clavulanate as a consolidative regimen, completing a roughly two-month antimicrobial course. Her symptoms, including gait instability and recurrent falls, resolved satisfactorily, with no concerning recurrence after discontinuation of antibiotics.  \nCategories: Medical Education, Internal Medicine, Infectious Disease  \nKeywords: lactobacillus bacteria, lactobacillus jensenii, lactobacillus species, vertebral discitis, vertebralosteomyelitis  \nIntroduction  \nVertebral and disc infections are most often associated with Gram-positive cocci and, less frequently, Gramnegative pathogens [1] . The most commonly isolated organisms from tested specimens include Staphylococcus aureus, coagulase-negative Staphylococcus species, and Streptococcus species [2] . Infections may spread hematogenously or contiguously from skin or visceral organ infections [1] . In immunosuppressed patients, less common organisms such as Mycobacterium tuberculosis, fungi, Pseudomonas aeruginosa, and, rarely, Lactobacillus species may be encountered [1,2] . Frequently reported predisposing factors include immunodeficiency states, vertebral surgery, intravenous drug use, intravenous catheter use, diabetes mellitus, infective endocarditis, malignancy, and dental infections or procedures [1,2] .  \nCase Presentation  \nWe present a case of a 63-year-old female who experienced progressive lower back pain and lower extremity weakness over a two-month period, resulting in gait instability and recurrent falls. Examination revealed flaccid paraparesis of the bilateral lower extremities with symmetric hyporeflexia. Bilateral Babinski reflexes and plantar responses were negative.  \nMRI demonstrated lumbosacral discitis and osteomyelitis, with a paravertebral phlegmonous process including small bilateral psoas abscesses and surrounding myositis. The source of infection was unclear, with no major risk factors identified other than pancytopenia of unclear etiology. Further evaluation of pancytopenia was unrevealing and included negative serologies for human immunodeficiency virus, hepatitis B, hepatitis C, Epstein-Barr virus, and cytomegalovirus. Vitamin B12 and folate levels were normal. There was no evidence of hemolysis, and the peripheral smear revealed no malignant cells. Biopsy staining was negative for acid-fast bacilli and fungal elements. Inflammatory markers were elevated. A transthoracic echocardiogram showed no vegetations.  \nHer medical history was notable for diabetes mellitus and maxillary dentures. She also reported prolonged vaginal bleeding following new sexual intercourse after many years of absti","cbCais8ohL08ioDx","https://ap.wps.com/l/cbCais8ohL08ioDx","pdf",2913694,"English","# Abstract\n# Introduction\n# Case Presentation\n# How to cite this article\n# Laboratory findings on admission\n# MRI figures","[{\"question\":\"Why was Lactobacillus jensenii considered unusual in this patient?\",\"answer\":\"Lactobacillus species are generally considered beneficial and are not typically pathogenic, and bloodstream or tissue infections are uncommon. In this case, vertebral discitis and osteomyelitis developed despite negative conventional cultures.\"},{\"question\":\"How was the diagnosis of Lactobacillus jensenii confirmed?\",\"answer\":\"L4-L5 disc biopsy was positive for L. jensenii using next-generation sequencing. Conventional tissue cultures were negative, while inflammatory markers were elevated.\"},{\"question\":\"What treatment was used and what was the outcome?\",\"answer\":\"The patient received piperacillin-tazobactam for six weeks, then transitioned to amoxicillin-clavulanate to complete an approximately two-month antimicrobial course. Gait instability and recurrent falls resolved satisfactorily, with no concerning recurrence after stopping antibiotics.\"}]","An Atypical Case of Lactobacillus jensenii Discitis and Osteomyelitis | PDF",1790753980,13]