[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-457008-105":59,"doc-detail-457008-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","an-association-of-mycoplasma-pneumonia-with-lung-function-and-laboratory-parameters","An association of Mycoplasma pneumonia with lung function and laboratory parameters","","A clinical study examines how Mycoplasma pneumoniae infection affects lung function over time in children aged 5 years and older. Participants included M. pneumoniae-infected children and healthy volunteers recruited from Nanjing Gaochun People’s Hospital between February 2022 and January 2023. Lung function was assessed at admission, discharge, and at 4, 8, and 12 months post-discharge, and dynamic recovery patterns were analyzed alongside laboratory parameters. Infection correlated with lung function and showed gradual improvement.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/an-association-of-mycoplasma-pneumonia-with-lung-function-and-laboratory-parameters/457008/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/an-association-of-mycoplasma-pneumonia-with-lung-function-and-laboratory-parameters/457008.png","ImageObject",300,407,{"name":92,"@type":93},"Mia  ","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"What is the main aim of this study?","Question",{"text":113,"@type":114},"To observe dynamic changes in lung function after Mycoplasma pneumoniae infection in children over a one-year period.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"When was lung function assessed in the participants?",{"text":118,"@type":114},"Lung function was assessed at admission, discharge, and at the 4th, 8th, and 12th months after discharge.",{"name":120,"@type":111,"acceptedAnswer":121},"Which factors were associated with lung function in infected children?",{"text":122,"@type":114},"Several factors correlated with lung function, including lymphocyte count, albumin, prealbumin, carbon dioxide levels, A/G ratio, triglycerides, and apolipoprotein B.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},457008,1790928304,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":105,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},687207024478,"https://ap-avatar.wpscdn.com/davatar_a8503ba1806abce46bf441b54a3ca4cd","[www. nature.com/scientificreports](www. nature.com/scientificreports)  \nOPEN  \nAn association of Mycoplasma pneumonia with lung function and laboratory parameters  \nPing Liu1,2, Anni Cao1, Xinyi Jia1, Qiangquan Rong2􀀍 & Feng Liu1􀀍  \nMycoplasma pneumoniae (M. pneumoniae) is a significant pathogen causing community-acquired pneumonia in children aged 5 years and older. While numerous studies have demonstrated that M. pneumoniae infection can impair lung function, the dynamic changes in lung function following M. pneumoniae infection remain poorly understood. This study aimed to observe the dynamic changes in lung function after M. pneumoniae infection in children. Children with M. pneumoniae infection and healthy volunteers were recruited from Nanjing Gaochun People’s Hospital between February 2022 and January 2023. The M. pneumoniae-infected children were followed up for one year, with lung function assessed at admission, discharge, and atthe 4th, 8th, and 12th months post-discharge. M. pneumoniae infection was found to be associated with lung function, which gradually recovered over time. Several factors were found to be associated with lung function, including lymphocyte count, albumin, prealbumin, carbon dioxide levels, A/G ratio, triglycerides, and apolipoprotein B. M. pneumoniae infection is indeed associated with pulmonary function in children.  \nKeywords Mycoplasma pneumonia, Lung function, Dynamics, Children  \nM. pneumoniae pneumonia is a notable cause of community-acquired pneumonia (CAP) in children, contributing to 10% to 40% of pediatric hospitalizations for CAP1. M. pneumoniae, the causative agent of M. pneumoniae pneumonia, is the smallest pathogenic microorganism that can live independently in cell-free culture media, positioned between bacteria and viruses. M. pneumoniae pneumonia refers to the pulmonary inflammation caused by M. pneumoniae infection, which can involve the bronchi, bronchioles, alveoli, and pulmonary interstitium. The condition may progress to severe M. pneumoniae pneumonia (SMPP)2. Some patients may progress even with active treatment, which is known as refractory M. pneumoniae pneumonia3.  \nThe incidence of M. pneumoniae pneumonia is increasing annually, particularly among children aged 5 to 15 years4, with a notable trend toward younger age groups5. M. pneumoniae infections tend to occur in periodic outbreaks, with infection rates reaching 30% to 50% during epidemic years6. In 2023, during the Mycoplasma pneumoniae pandemic, data from the Shanghai Hospital Healthcare Quality Assessment and Improvement Platform revealed that M. pneumoniae pneumonia cases in Shanghai began to rise in June and July 2023, peaking in October and November7. In the eastern region of the country, analysis of over 30,000 PCR specimens and bronchoscopies showed a 50% positive rate for M. pneumoniae since July 20238.Pathogen surveillance revealed that, although multiple pathogens were detected, M. pneumoniae infection was the predominant one9. According to data from Beijing, in the fall and winter of 2023, the positive detection rate of M. pneumoniae was 25.4% in outpatients, 48.4% in hospitalized children, and as high as 61.1% in children with respiratory symptoms. In respiratory wards, over 50% of the hospitalized children were diagnosed with M. pneumoniae pneumonia10.  \nMultiple studies have shown that infection with M. pneumoniae may lead to a decline in lung function11, 12, 13, and M. pneumoniae is closely related to wheezing in children and even the onset of asthma14, 15, 16. Infection is the most important trigger for worsening asthma. Rhinovirus (RV) is a common cold virus and the most prevalent pathogen constantly spreading in the community. Respiratory syncytial virus (RSV) has long been considered the cause of lower respiratory tract infections in infants. Wheezing caused by both of these viruses is associated with subsequent asthma17. Human parainfluenza virus, coronavirus, influenza virus, adenovirus, boca","cbCaiax7a8q2ht36","https://ap.wps.com/l/cbCaiax7a8q2ht36","pdf",4876210,"English","# Introduction\n## Background: Mycoplasma pneumoniae in pediatric community-acquired pneumonia\n## Rationale: limited knowledge of recovery-phase lung function dynamics\n## Study design and aims","[{\"question\":\"What is the main aim of this study?\",\"answer\":\"To observe dynamic changes in lung function after Mycoplasma pneumoniae infection in children over a one-year period.\"},{\"question\":\"When was lung function assessed in the participants?\",\"answer\":\"Lung function was assessed at admission, discharge, and at the 4th, 8th, and 12th months after discharge.\"},{\"question\":\"Which factors were associated with lung function in infected children?\",\"answer\":\"Several factors correlated with lung function, including lymphocyte count, albumin, prealbumin, carbon dioxide levels, A/G ratio, triglycerides, and apolipoprotein B.\"}]","An association of Mycoplasma pneumonia with lung function and laboratory parameters | PDF",1790747977,28]