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The work combines clinical translation with technological innovation by building a sarcopenia database and biobank and supporting a 2024 standardized biobank and database expert consensus. It adds an AI diagnostic system, MFIAS, automating CT-based muscle quantification and enabling multidimensional metrics analysis, while a newly built rehabilitation unit uses isokinetic dynamometry for personalized training.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/advancing-sarcopenia-management-through-integrated-clinical-research-translation-and-innovation-abstract/428697/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/advancing-sarcopenia-management-through-integrated-clinical-research-translation-and-innovation-abstract/428697.png","ImageObject",300,407,{"name":92,"@type":93},"Rainbow Cat","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-02","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":39},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What integrated approach is used to address sarcopenia?","Question",{"text":112,"@type":113},"The document describes a multidimensional integration of clinical translation and technological innovation, combining a database/biobank with AI diagnostics and rehabilitation systems.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How does the AI diagnostic system (MFIAS) contribute?",{"text":117,"@type":113},"MFIAS automates CT-based muscle quantification and improves efficiency versus manual workflows, shifting analysis from single parameters to multidimensional metrics.",{"name":119,"@type":110,"acceptedAnswer":120},"What rehabilitation methods are implemented and what outcomes are reported?",{"text":121,"@type":113},"The rehabilitation unit uses isokinetic dynamometry testing and personalized training protocols, showing short-term improvements in physical performance scores and metabolic parameters.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},428697,1790816414,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":39,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":14,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":24,"preview_page_count":4},962090769181,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","Innovation in Aging, 2025, Vol. 9, No. S2 377  \nAbstract citation ID: igaf122.1282  \nADVANCING SARCOPENIA MANAGEMENT THROUGH INTEGRATED CLINICAL-RESEARCH TRANSLATION AND INNOVATION  \nYaomin Hu, Renji Hospital, Shanghai, Shanghai, China  \n(People’s Republic)  \nSarcopenia is closely linked to aging, driving our comprehensive clinical and scientific efforts to address this condition through a multidimensional integration of clinical translation and technological innovation. We established a database and biobank for sarcopenia, which formed the foundation for leading the development of the 2024 Chinese Expert Consensus on the Construction of Standardized Biobank and Database for Sarcopenia. This initiative has fostered a collaborative medical consortium network for sarcopenia management. Our self-developed AI diagnostic system, Muscle and Fat Intelligent Analysis System (MFIAS), automates CT-based muscle quantification, significantly improving analytical efficiency compared to the traditional manual approach, while shifting from single-parameter to multidimensional metrics analysis. The newly constructed skeletal muscle rehabilitation unit employs isokinetic dynamometry testing and training systems, demonstrating short-term improvements in physical performance scores and  \n378 Innovation in Aging, 2025, Vol. 9, No. S2  \nmetabolic parameters through personalized treatment protocols.  \nIn addition, in collaboration with the School of Basic Medical Sciences, we have established a basic science research team to investigate the molecular mechanisms underlying skeletal muscle aging. These innovations align with global trends in precision geriatrics, offering scalable solutions for promoting healthy aging for the ever-growing older adult population. By redefining sarcopenia as a modifiable aging trajectory rather than an inevitable decline, our work provides an actionable framework for early intervention and multidisciplinary care, addressing one of the most pressing challenges in gerontological health.","cbCaiuilQpoQD2gf","https://ap.wps.com/l/cbCaiuilQpoQD2gf","pdf",717915,"English","# Abstract","[{\"question\":\"What integrated approach is used to address sarcopenia?\",\"answer\":\"The document describes a multidimensional integration of clinical translation and technological innovation, combining a database/biobank with AI diagnostics and rehabilitation systems.\"},{\"question\":\"How does the AI diagnostic system (MFIAS) contribute?\",\"answer\":\"MFIAS automates CT-based muscle quantification and improves efficiency versus manual workflows, shifting analysis from single parameters to multidimensional metrics.\"},{\"question\":\"What rehabilitation methods are implemented and what outcomes are reported?\",\"answer\":\"The rehabilitation unit uses isokinetic dynamometry testing and personalized training protocols, showing short-term improvements in physical performance scores and metabolic parameters.\"}]","ADVANCING SARCOPENIA MANAGEMENT THROUGH INTEGRATED CLINICAL-RESEARCH TRANSLATION AND INNOVATION - Abstract | PDF",1790647360]