[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-336591-105":59,"doc-detail-336591-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","advances-in-medicine-photodynamic-therapy-review","Advances in Medicine: Photodynamic Therapy - Review","","Over the past decades, medicine has made major progress through modern technologies and innovative therapeutic approaches, with photodynamic therapy (PDT) emerging as a particularly promising direction. PDT combines light of a specific wavelength with designed photosensitizing substances to target cancer cells, bacterial infections, and other treatment-resistant diseases. By activating photosensitizers with properly adjusted light, PDT can induce cell death while reducing injury to surrounding healthy tissues. The article examines mechanisms, clinical uses, and future development prospects, including recent research and patient experiences.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/advances-in-medicine-photodynamic-therapy-review/336591/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/advances-in-medicine-photodynamic-therapy-review/336591.png","ImageObject",300,407,{"name":92,"@type":93},"Ezra","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-27","2026-09-21",true,{"@type":102,"interactionType":103,"userInteractionCount":44},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What is photodynamic therapy (PDT) and how does it work?","Question",{"text":112,"@type":113},"PDT uses light of a specific wavelength together with specially designed photosensitizing substances. Appropriate light activation can induce death of cancer or bacterial cells while minimizing damage to surrounding healthy tissues.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Which diseases does the article connect PDT with?",{"text":117,"@type":113},"The text highlights potential roles in the fight against cancer and bacterial infections, as well as other diseases resistant to traditional treatment methods.",{"name":119,"@type":110,"acceptedAnswer":120},"How is the historical development of PDT described in the introduction?",{"text":121,"@type":113},"The introduction traces mentions of PDT back to ancient civilizations and then discusses further developments in Europe during the 18th and 19th centuries, leading into major advances in the 20th century.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},336591,1790108364,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":44,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":139,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145},1099514068035,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","Review  \nAdvances in Medicine: Photodynamic Therapy  \nDavid Aebisher 1, *, Jakub Szpara 2 and Dorota Bartusik-Aebisher 3  \nCitation: Aebisher, D.; Szpara, J.; Bartusik-Aebisher, D. Advances in Medicine: Photodynamic Therapy. Int. J. Mol. Sci. 2024, 25, 8258 . [https://doi.org/10.3390/](https://doi.org/10.3390/)[ ](https://doi.org/10.3390/)ijms25158258  \nAcademic Editors: Bertrand Liagre and Young-Il Jeong  \nReceived: 11 May 2024  \nRevised: 24 July 2024  \nAccepted: 25 July 2024  \nPublished: 29 July 2024  \nCopyright: © 2024 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license ([https://](https://)[ ](https://)[creativecommons.org/licenses/by/](creativecommons.org/licenses/by/)[ ](creativecommons.org/licenses/by/)[4.0/](4.0/)) .  \n1 Department of Photomedicine and Physical Chemistry, Medical College of The Rzeszów University, 35-025 Rzeszów, Poland  \n2 English Division Science Club, Medical College of The Rzeszów University, 35-025 Rzeszów, Poland; [js126214@stud.ur.edu.pl](js126214@stud.ur.edu.pl)  \n3 Department of Biochemistry and General Chemistry, Medical College of The Rzeszów University, 35-025 Rzeszów, Poland; [dbartusikaebisher@ur.edu.pl](dbartusikaebisher@ur.edu.pl)  \n* Correspondence: [daebisher@ur.edu.pl](daebisher@ur.edu.pl)  \nAbstract: Over the past decades, medicine has made enormous progress, revolutionized by modern technologies and innovative therapeutic approaches. One of the most exciting branches of these developments is photodynamic therapy (PDT) . Using a combination of light of a specific wavelength and specially designed photosensitizing substances, PDT offers new perspectives in the fight against cancer, bacterial infections, and other diseases that are resistant to traditional treatment methods. In today’s world, where there is a growing problem of drug resistance, the search for alternative therapies is becoming more and more urgent. Imagine that we could destroy cancer cells or bacteria using light, without the need to use strong chemicals or antibiotics. This is what PDT promises. By activating photosensitizers using appropriately adjusted light, this therapy can induce the death of cancer or bacterial cells while minimizing damage to surrounding healthy tissues. In this work, we will explore this fascinating method, discovering its mechanisms of action, clinical applications, and development prospects. We will also analyze the latest research and patient testimonies to understand the potential of PDT for the future of medicine.  \nKeywords: photodynamic therapy; photosensitizers; history of photodynamic therapy; in vitro; in vivo; nanotechnology; development; cancer therapies  \n1. Introduction  \n1.1. Advances in PDT Research in Ancient Civilizations  \nPhotodynamic therapy (PDT) and its history may go back further than you might think. The first mentions and evidence of the use of this therapy date back several thousand years. In ancient civilizations such as Egypt, India, or China, where, by appropriately combining the rays of sunlight with plants and vegetables, it was possible to obtain appropriate reactions. Thanks to this special combination, they treated diseases such as:  \n• Psoriasis, which manifests itself as red spots and silvery scales resulting from the excessive multiplication of skin cells;  \n• Vitiligo, i.e., a disorder of melanin production, resulting in white spots all over the body;  \n• Rickets, caused by vitamin D deficiency [1–3] .  \nThe method used by the ancient Egyptians to pigment de-pigmented skin lesions was to produce a special powder, which included, among others, parsnip, parsley, or St. John’s wort, and then it was applied to designated areas on the skin and exposed to light, which caused skin pigmentation [4] .  \nIn China, these methods were completely different. An innovative therapy was introduced to these areas by Lingyan Tzu-Ming in the f","cbCaievjMENbcgwW","https://ap.wps.com/l/cbCaievjMENbcgwW","pdf",946382,22,"English","# Abstract\n# Keywords\n# 1. Introduction\n## 1.1. Advances in PDT Research in Ancient Civilizations\n## 1.2. Advances in PDT Research in the 18th and 19th Centuries","[{\"question\":\"What is photodynamic therapy (PDT) and how does it work?\",\"answer\":\"PDT uses light of a specific wavelength together with specially designed photosensitizing substances. Appropriate light activation can induce death of cancer or bacterial cells while minimizing damage to surrounding healthy tissues.\"},{\"question\":\"Which diseases does the article connect PDT with?\",\"answer\":\"The text highlights potential roles in the fight against cancer and bacterial infections, as well as other diseases resistant to traditional treatment methods.\"},{\"question\":\"How is the historical development of PDT described in the introduction?\",\"answer\":\"The introduction traces mentions of PDT back to ancient civilizations and then discusses further developments in Europe during the 18th and 19th centuries, leading into major advances in the 20th century.\"}]","Advances in Medicine: Photodynamic Therapy - Review | PDF",1790015757,55]