[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-382012-105":3,"detail-sidebar-cat-0-en-105":81,"doc-detail-382012-en":130},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":74,"head_meta":76,"extra_data":78,"updated_unix":80},105,"en","advanced-magnetic-resonance-imaging-of-mixed-mucinous-breast-cancer-a-case-report","Advanced magnetic resonance imaging of mixed mucinous breast cancer: A case report","","Well-differentiated adenocarcinoma represents a rare infiltrating ductal carcinoma subtype of breast mucinous cancer, accounting for about 2% of invasive cases. Pure and mixed mucinous carcinomas differ by mucin proportion and tumor cellularity, which affects prognosis and therapy. Surgery remains the primary treatment despite limited evidence for special forms. The report presents a case of mixed mucinous carcinoma in a 52-year-old woman evaluated using advanced breast MRI.",{"@graph":14,"@context":73},[15,34,56],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/advanced-magnetic-resonance-imaging-of-mixed-mucinous-breast-cancer-a-case-report/382012/",4,{"url":32,"name":10,"@type":35,"image":36,"author":41,"headline":10,"publisher":44,"fileFormat":47,"inLanguage":8,"description":12,"dateModified":48,"datePublished":49,"encodingFormat":47,"isAccessibleForFree":50,"interactionStatistic":51},"DigitalDocument",{"url":37,"@type":38,"width":39,"height":40},"https://docshare.wps.com/thumbnails/advanced-magnetic-resonance-imaging-of-mixed-mucinous-breast-cancer-a-case-report/382012.png","ImageObject",300,407,{"name":42,"@type":43},"RuangKosong","Person",{"url":19,"name":45,"@type":46},"DocShare","Organization","application/pdf","2026-10-30","2026-09-24",true,{"@type":52,"interactionType":53,"userInteractionCount":55},"InteractionCounter",{"@type":54},"ViewAction",7,{"@type":57,"mainEntity":58},"FAQPage",[59,65,69],{"name":60,"@type":61,"acceptedAnswer":62},"What distinguishes pure versus mixed mucinous breast carcinoma?","Question",{"text":63,"@type":64},"They are classified by the amount of mucin and tumor cellularity. Mixed carcinoma includes an infiltrating ductal epithelial component without mucin, while pure type mainly consists of tumor tissue with extracellular mucin synthesis in over 90% of the tumor.","Answer",{"name":66,"@type":61,"acceptedAnswer":67},"How was the breast lesion evaluated in this case?",{"text":68,"@type":64},"The patient underwent ultrasound and advanced MRI, including T1/T2-weighted sequences with fat suppression, diffusion assessment, perfusion features, and magnetic resonance spectroscopy.",{"name":70,"@type":61,"acceptedAnswer":71},"What were the key histopathology results?",{"text":72,"@type":64},"Core needle biopsy showed mixed mucinous breast carcinoma. Immunohistochemical analysis further characterized the lesion, supporting the final diagnosis.","https://schema.org",{"og:url":32,"og:type":75,"og:title":10,"og:site_name":45,"og:description":12},"article",{"robots":77,"canonical":32},"index,follow",{"doc_id":79,"site_id":7},382012,1790828385,{"code":4,"msg":82,"data":83},"success",[84,88,92,96,101,106,109,114,119,122,126],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":85,"show_sort_weight":86,"slug":87},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":89,"show_sort_weight":90,"slug":91},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":93,"show_sort_weight":94,"slug":95},"Exam",70,"exam",{"id":97,"doc_module":4,"doc_module_name":25,"category_name":98,"show_sort_weight":99,"slug":100},5,"Comic",60,"comic",{"id":102,"doc_module":4,"doc_module_name":25,"category_name":103,"show_sort_weight":104,"slug":105},6,"Technology",50,"technology",{"id":55,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":107,"slug":108},40,"healthcare",{"id":110,"doc_module":4,"doc_module_name":25,"category_name":111,"show_sort_weight":112,"slug":113},8,"Research & Report",30,"research-report",{"id":115,"doc_module":4,"doc_module_name":25,"category_name":116,"show_sort_weight":117,"slug":118},9,"Religion & Spirituality",20,"religion-spirituality",{"id":117,"doc_module":4,"doc_module_name":25,"category_name":120,"show_sort_weight":117,"slug":121},"World Cup","world-cup",{"id":123,"doc_module":4,"doc_module_name":25,"category_name":124,"show_sort_weight":123,"slug":125},10,"Lifestyle","lifestyle",{"id":127,"doc_module":4,"doc_module_name":25,"category_name":128,"show_sort_weight":97,"slug":129},19,"General","general",{"code":4,"msg":82,"data":131},{"doc_id":79,"user_id":132,"nickname":42,"user_avatar":133,"doc_module":4,"category_id":55,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":55,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":97,"language":139,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":12,"update_tm":143,"read_time":144},962090883219,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","Radiology Ca s e Reports 18 (2023) 1053 – 1057  \nAvailable online [at](at www.sciencedirect.com)[ www.sciencedirect.com](at www.sciencedirect.com)  \njournal [homepage:](homepage: www.elsevier.com/locate/radcr)[ www.elsevier.com/locate/radcr](homepage: www.elsevier.com/locate/radcr)  \n| Case Report\u003Cbr>Advanced magnetic resonance imaging of mixed mucinous breast cancer: A case report ✩\u003Cbr>Huynh-Thi Do Quyen, MDa,1, Nguyen Minh Duc, MDa,b,1,∗, Nguyen Anh Huy, MDa, Cao Minh Tri, MDa, Bui-Thi Thanh Truc, MDa, Nguyen Tin Trung, MDa, Au Nguyet Dieu, MD, PhDc,d, Pham Xuan Dung, MD, PhDe,1\u003Cbr>a Department of Radiology, Ho Chi Minh City Oncology Hospital, Ho Chi Minh City, Vietnam\u003Cbr>b Department of Radiology, Pham Ngoc Thach University of Medicine, 2 Duong Quang Trung Ward 12 District 10, Ho Chi Minh City, Vietnam\u003Cbr>c Department of Pathology, Ho Chi Minh City Oncology Hospital, Ho Chi Minh City, Vietnam d Department of Pathology, Pham Ngoc Thach University of Medicine, Ho Chi Minh City, Vietnam e Director board, Ho Chi Minh City Oncology Hospital, Ho Chi Minh City, Vietnam |  |  |\n| --- | --- | --- |\n| a r t i c l e i n f o |  | a b s t r a c t |\n| Article history:\u003Cbr>Received 7 October 2022 Revised 6 December 2022 Accepted 10 December 2022 |  | Well-differentiated adenocarcinoma, a rare subtype of infiltrating ductal carcinoma, is a kind of mucinous cancer of the breast. It accounts for around 2% of all invasive breast cancers. The average age of presentation is 65-70 years, whereas women under the age of 35 account for 1% of cases. They are classified as pure or mixed carcinomas depending on the amount of mucin they include; knowing the difference is crucial for prognosis and therapy. Despite the lack of sufficient proof, the primary therapy for breast cancer is still surgery. Special forms of breast cancer are still being treated, although this is still a contentious topic. In this article, we intended to present a case of a mixed mucinous carcinoma in a 52-year-old female who was assessed by advanced magnetic resonance imaging.\u003Cbr>© 2022 The Authors. Published by Elsevier Inc. on behalf of University of Washington.\u003Cbr>This is an open access article under the CC BY-NC-ND license\u003Cbr>([http://creativecommons.org/licenses/by-nc-nd/4.0/](http://creativecommons.org/licenses/by-nc-nd/4.0/)) |\n| Keywords:\u003Cbr>Breast cancer\u003Cbr>Mucinous carcinoma\u003Cbr>Ultrasound\u003Cbr>Magnetic resonance imaging |  |  |\n\nIntroduction  \nMucinous carcinoma of the breast, also known as colloid breast cancer, which makes up around 2% of all breast carcinomas, is a very uncommon subtype of breast cancer according to the most recent WHO classification of breast malignancies [1] . Mucinous breast cancer starts in the milk duct of the breast  \nbefore spreading to the tissues near the duct, just like other forms of invasive ductal cancer. Pure type mucinous carcinomas and mixed type mucinous carcinomas are the 2 kinds of mucinous carcinomas, which are differentiated by the tumor’s cellularity. The mixed form also includes an infiltrating ductal epithelial component without mucin, whereas the pure type only comprises of tumor tissue with extracellular mucin synthesis in over 90% of the tumor [2] . A low likelihood of lymph  \n✩ Competing Interests: The authors have no conflicts of interest to declare.  \n∗ Corresponding author.  \nE-mail [address:](address: bsnguyenminhduc@pnt.edu.vn)[ bsnguyenminhduc@pnt.edu.vn](address: bsnguyenminhduc@pnt.edu.vn) (N.M. Duc).  \n1 These authors contributed equally to this article as co-first authors.  \n[https://doi.org/10.1016/j.radcr.2022.12.027](https://doi.org/10.1016/j.radcr.2022.12.027)  \n1930-0433/© 2022 The Authors. Published by Elsevier Inc. on behalf of University of Washington. This is an open access article under the CC BY-NC-ND license ([http://creativecommons.org/licenses/by-nc-nd/4.0/](http://creativecommons.org/licenses/by-nc-nd/4.0/))  \nFig. 1 – Ultrasound images. (A) The distance from the skin to the lesion (arrow) was 8 mm. ","cbCaiqN4Y6BD8wg2","https://ap.wps.com/l/cbCaiqN4Y6BD8wg2","pdf",1822310,"English","# Introduction\n# Case description\n# MRI and imaging findings\n# Biopsy and histopathology\n# Immunohistochemical analysis","[{\"question\":\"What distinguishes pure versus mixed mucinous breast carcinoma?\",\"answer\":\"They are classified by the amount of mucin and tumor cellularity. Mixed carcinoma includes an infiltrating ductal epithelial component without mucin, while pure type mainly consists of tumor tissue with extracellular mucin synthesis in over 90% of the tumor.\"},{\"question\":\"How was the breast lesion evaluated in this case?\",\"answer\":\"The patient underwent ultrasound and advanced MRI, including T1/T2-weighted sequences with fat suppression, diffusion assessment, perfusion features, and magnetic resonance spectroscopy.\"},{\"question\":\"What were the key histopathology results?\",\"answer\":\"Core needle biopsy showed mixed mucinous breast carcinoma. Immunohistochemical analysis further characterized the lesion, supporting the final diagnosis.\"}]","Advanced magnetic resonance imaging of mixed mucinous breast cancer: A case report | PDF",1790248565,13]