[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-424415-105":59,"doc-detail-424415-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","adaptations-in-energy-expenditure-following-caloric-restriction-in-older-adults","Adaptations in Energy Expenditure Following Caloric Restriction in Older Adults","","Energy expenditure (EE) adapts to caloric restriction (CR) and may help explain why weight regain occurs after weight loss. The magnitude of EE changes after CR remains unclear in older adults. This study assessed changes in total EE using doubly labeled water (DLW) and resting EE using indirect calorimetry after 9-month HALLO-P CR interventions, and evaluated adaptive thermogenesis beyond changes expected from body size and composition.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/adaptations-in-energy-expenditure-following-caloric-restriction-in-older-adults/424415/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/adaptations-in-energy-expenditure-following-caloric-restriction-in-older-adults/424415.png","ImageObject",300,407,{"name":92,"@type":93},"Kurz","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":34},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"How were total and resting energy expenditure measured after caloric restriction?","Question",{"text":112,"@type":113},"Total energy expenditure was measured using doubly labeled water (DLW), and resting energy expenditure was measured using indirect calorimetry after the 9-month HALLO-P caloric restriction interventions.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What happened to total and resting energy expenditure following caloric restriction?",{"text":117,"@type":113},"Both total EE (TEE) and resting EE (REE) decreased slightly but not significantly after CR, with TEE showing a change of -47±353 kcal/day and REE showing -59±218 kcal/day.",{"name":119,"@type":110,"acceptedAnswer":120},"Did adaptive thermogenesis increase after caloric restriction in older adults?",{"text":121,"@type":113},"Adaptive thermogenesis for both TEE and REE showed non-significant increases after CR, and the findings suggest little adaptive thermogenesis to moderate CR over 9 months in older adults.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},424415,1790863315,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":34,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":8,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":81,"preview_page_count":4},2336478945635,"https://ap-avatar.wpscdn.com/davatar_6f874abed73319feea01a86fa6f0fab8","302 Innovation in Aging, 2025, Vol. 9, No. S2  \nAbstract citation ID: igaf122.1019  \nADAPTATIONS IN ENERGY EXPENDITURE  \nFOLLOWING CALORIC RESTRICTION IN  \nOLDER ADULTS  \nDenise Houston1, Jason Fanning2, James DeLany3, Fang-Chi Hsu1, Shyh-Huei Chen1, Michael Miller1, Stephen Kritchevsky1, and Barbara Nicklas1, 1. Wake Forest University School of Medicine, Winston-Salem, North Carolina, United States,  \n2. Wake Forest University, Winston Salem, North Carolina, United States, 3. AdventHealth, Orlando, Florida, United States  \nAdaptations in components of energy expenditure (EE) occur in response to caloric restriction (CR) and contribute to the propensity for weight regain following weight loss. However, the magnitude of changes in EE following CR is not well known in older adults. We examined changes in total EE (TEE by doubly labeled water, DLW) and resting EE (REE by indirect calorimetry) following the 9-month HALLO-P CR interventions. The degree of adaptive thermogenesis (AT; defined as changes in EE beyond what is expected from changes in body size and composition) was also analyzed. Among 56 older adults with overweight/obesity (68±5 yrs; 61% female; 31.6±3.0 kg/m2) who were randomized to CR, the degree of CR over 9 months was estimated as 7.9% based on the intake-balance method with DLW-TEE used to estimate energy intake. This degree of CR decreased body weight by 6.4±5.4 kg (-7.0%) and fat free mass (FFM) by  \n2.1±1.9 kg (-4.0%) . Baseline raw values of TEE and REE were 2327±449 and 1619±297 kcal/day, respectively. Both TEE and REE decreased slightly, but not significantly, following CR (TEE:Δ= -47±353 kcal/d, \u003C0 .5%; REE: Δ = -59±218 kcal/d, 3.6%) . Adaptive thermogenesis forTEE and REE (adjusted for age, race, sex, and baseline height, weight, fat-free mass, fat mass, and step count) showed non-significant increases after CR (TEE-AT: 48±342 kcal/d; REE-AT: 29±185 kcal/d). We will also report the relationship of these adaptations to changes in body mass and FFM. These results suggest little adaptive thermogenesis to moderate CR over 9 months in older adults.","cbCainl6bP1ljusT","https://ap.wps.com/l/cbCainl6bP1ljusT","pdf",317777,"English","# Abstract\n## Study design and measures\n## Results on total and resting EE\n## Adaptive thermogenesis and conclusions","[{\"question\":\"How were total and resting energy expenditure measured after caloric restriction?\",\"answer\":\"Total energy expenditure was measured using doubly labeled water (DLW), and resting energy expenditure was measured using indirect calorimetry after the 9-month HALLO-P caloric restriction interventions.\"},{\"question\":\"What happened to total and resting energy expenditure following caloric restriction?\",\"answer\":\"Both total EE (TEE) and resting EE (REE) decreased slightly but not significantly after CR, with TEE showing a change of -47±353 kcal/day and REE showing -59±218 kcal/day.\"},{\"question\":\"Did adaptive thermogenesis increase after caloric restriction in older adults?\",\"answer\":\"Adaptive thermogenesis for both TEE and REE showed non-significant increases after CR, and the findings suggest little adaptive thermogenesis to moderate CR over 9 months in older adults.\"}]","Adaptations in Energy Expenditure Following Caloric Restriction in Older Adults | PDF",1790634126]