[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-seo-25376-105":3,"detail-sidebar-cat-0-en-105":57,"doc-detail-25376-en":107},{"code":4,"msg":5,"data":6},0,"ok",{"site_id":7,"language":8,"slug":9,"title":10,"keywords":11,"description":12,"schema_data":13,"social_meta":50,"head_meta":52,"extra_data":54,"updated_unix":56},105,"en","acute-renal-failure-causes","Acute Renal Failure Causes","","Acute renal failure presents as a rapid, potentially reversible loss of kidney function over days to weeks, with classification by cause: pre-renal causes reflect decreased renal perfusion leading to reduced GFR and often acute tubular necrosis (ATN); renal causes involve primary injury to the kidney such as severe glomerulonephritis, ATN from drugs/toxins or prolonged hypoperfusion, acute tubulo-interstitial nephritis, drug-related nephrotoxicity, rhabdomyolysis, bilateral infection, and vascular kidney disease. Post-renal causes arise from urinary tract obstruction, raising ureteral pressure and causing hydronephrosis and decreased GFR. Clinical features and diagnostic clues include urine output and creatinine rise, electrolyte and acid-base disturbances, and urine cast patterns, enabling targeted management and dialysis indications when complications occur.",{"@graph":14,"@context":49},[15,34],{"@type":16,"itemListElement":17},"BreadcrumbList",[18,23,27,31],{"item":19,"name":20,"@type":21,"position":22},"https://docshare.wps.com","Home","ListItem",1,{"item":24,"name":25,"@type":21,"position":26},"https://docshare.wps.com/document/","Document",2,{"item":28,"name":29,"@type":21,"position":30},"https://docshare.wps.com/document/healthcare/","Healthcare",3,{"item":32,"name":10,"@type":21,"position":33},"https://docshare.wps.com/document/acute-renal-failure-causes/25376",4,{"url":32,"name":10,"@type":35,"author":36,"headline":10,"publisher":39,"fileFormat":42,"description":12,"dateModified":43,"datePublished":43,"encodingFormat":42,"isAccessibleForFree":44,"interactionStatistic":45},"DigitalDocument",{"name":37,"@type":38},"Aurora","Person",{"url":19,"name":40,"@type":41},"DocShare","Organization","application/pdf","2026-05-07",true,{"@type":46,"interactionType":47,"userInteractionCount":4},"InteractionCounter",{"@type":48},"ViewAction","https://schema.org",{"og:url":32,"og:type":51,"og:title":10,"og:site_name":40,"og:description":12},"article",{"robots":53,"canonical":32},"index,follow",{"doc_id":55,"site_id":7},25376,1778192400,{"code":4,"msg":58,"data":59},"success",[60,64,68,72,77,82,86,91,96,99,103],{"id":22,"doc_module":4,"doc_module_name":25,"category_name":61,"show_sort_weight":62,"slug":63},"Story & Novel",90,"story-novel",{"id":26,"doc_module":4,"doc_module_name":25,"category_name":65,"show_sort_weight":66,"slug":67},"Literature",80,"literature",{"id":33,"doc_module":4,"doc_module_name":25,"category_name":69,"show_sort_weight":70,"slug":71},"Exam",70,"exam",{"id":73,"doc_module":4,"doc_module_name":25,"category_name":74,"show_sort_weight":75,"slug":76},5,"Comic",60,"comic",{"id":78,"doc_module":4,"doc_module_name":25,"category_name":79,"show_sort_weight":80,"slug":81},6,"Technology",50,"technology",{"id":83,"doc_module":4,"doc_module_name":25,"category_name":29,"show_sort_weight":84,"slug":85},7,40,"healthcare",{"id":87,"doc_module":4,"doc_module_name":25,"category_name":88,"show_sort_weight":89,"slug":90},8,"Research & Report",30,"research-report",{"id":92,"doc_module":4,"doc_module_name":25,"category_name":93,"show_sort_weight":94,"slug":95},9,"Religion & Spirituality",20,"religion-spirituality",{"id":94,"doc_module":4,"doc_module_name":25,"category_name":97,"show_sort_weight":94,"slug":98},"World Cup","world-cup",{"id":100,"doc_module":4,"doc_module_name":25,"category_name":101,"show_sort_weight":100,"slug":102},10,"Lifestyle","lifestyle",{"id":104,"doc_module":4,"doc_module_name":25,"category_name":105,"show_sort_weight":73,"slug":106},19,"General","general",{"code":4,"msg":58,"data":108},{"doc_id":55,"user_id":109,"nickname":37,"user_avatar":110,"doc_module":4,"category_id":83,"category_name":29,"doc_title":10,"doc_description":12,"doc_content":11,"file_id":111,"file_url":112,"file_type":113,"file_size":114,"view_count":4,"is_deleted":4,"is_public":22,"is_downloadable":22,"audit_status":22,"page_count":33,"language":115,"language_code":8,"site_id":7,"html_lang":8,"table_of_contents":11,"faqs":11,"seo_title":116,"seo_description":12,"update_tm":56,"read_time":100},4810365810221,"https://ap-avatar.wpscdn.com/davatar_155a257f0dc6eb9ab79c44ca47cae57d","cbCaieEvtEjPyYes","https://ap.wps.com/l/cbCaieEvtEjPyYes","pdf",413308,"English","Acute Renal Failure Causes | PDF"]