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Using randomized sequences with walking or rest first, participants completed brief phone-based assessments at baseline, right after each period, and between two treatment conditions. Outcomes included processing speed (symbol search), visuospatial memory (grid memory), and visual memory (color shapes). In 52 participants, walking improved visuospatial memory via shorter grid memory error distances, while processing speed and visual memory showed no significant walking effects.",{"@graph":69,"@context":127},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/acute-effects-of-a-short-bout-of-walking-on-domain-specific-cognition-in-adults-with-knee-replacement-poster-session/424496/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/acute-effects-of-a-short-bout-of-walking-on-domain-specific-cognition-in-adults-with-knee-replacement-poster-session/424496.png","ImageObject",300,407,{"name":92,"@type":93},"Blitz","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-04","2026-09-28",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119,123],{"name":110,"@type":111,"acceptedAnswer":112},"Why focus on short bouts of walking after knee replacement?","Question",{"text":113,"@type":114},"Adults with TKR often remain physically inactive, and longer activity may be difficult due to reduced functioning. The study tests whether a shorter bout could be more feasible while lowering risk related to ADRD.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"How was cognition measured in the study?",{"text":118,"@type":114},"Cognition was assessed with brief phone-based tests at baseline and immediately after each period. Symbol search measured processing speed, grid memory measured visuospatial memory, and color shapes measured visual memory.",{"name":120,"@type":111,"acceptedAnswer":121},"What cognitive domain improved after a 6-minute walk?",{"text":122,"@type":114},"The 6-minute walk was associated with improved visuospatial memory, shown by shorter error distances on the grid memory test.",{"name":124,"@type":111,"acceptedAnswer":125},"Did walking also improve processing speed or visual memory?",{"text":126,"@type":114},"No. The walking effect was not observed for processing speed or visual memory based on the reported model estimates and p-values.","https://schema.org",{"og:url":83,"og:type":129,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":131,"canonical":83},"index,follow",{"doc_id":133,"site_id":62},424496,1790817619,{"code":4,"msg":5,"data":136},{"doc_id":133,"user_id":137,"nickname":92,"user_avatar":138,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":139,"file_id":140,"file_url":141,"file_type":142,"file_size":143,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":8,"language":144,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":145,"faqs":146,"seo_title":147,"seo_description":67,"update_tm":148,"read_time":81,"preview_page_count":4},24464137899374,"https://us-avatar.wpscdn.com/davatar_3d24733baf745e90a7e4bdd5f77d97b2","954 Innovation in Aging, 2025, Vol. 9, No. S2  \nSESSION 7435 (POSTER)  COGNITION IV  \nAbstract citation ID: igaf122.3223  \nACUTE EFFECTS OF A SHORT BOUT OF WALKING ON DOMAIN-SPECIFIC COGNITION IN ADULTS WITH KNEE REPLACEMENT  \nJongwon Lee, Scott Jamieson, Clare Kennerley, Christine Pellegrini, and Chih-Hsiang Yang, University of South Carolina, Columbia, South Carolina, United States  \nThe total knee replacement (TKR) is a common elective surgery in older adults, and adults with TKR remain physically inactive and are at high risk for Alzheimer’s and related dementia (ADRD). Shorter bouts of walking may be more feasible for this population to reduce the risk of ADRD because prolonged physical activity could be challenging due to lower physical functioning. This study investigated the acute effects of the 6-minute walk on processing speed, visuospatial memory, and visual memory in adults with a history of TKR ≤ 6 months ago. They were randomized into two sequences with two periods: 6 minutes of walking or resting first. Cognition was assessed via brief phone-based tests at baseline, immediately after the first and second periods. Symbol search, grid memory, and color shapes tests were used to measure processing speed, visuospatial memory, and visual memory, respectively. The analysis included 52 participants (female = 40 (77%), age = 65.06 (9.06) yrs, time since surgery = 94.08 (21.66) days). Controlling for demographics and potential learning effects, mixed-effects models revealed that 6 minutes of walking was associated with improved visuospatial memory, as indicated by shorter error distances on the grid memory test (b = -3.87, p = 0.04) . The walking effect was not observed for processing speed (b = 178.82, p= 0.45) or visual memory (b = 0.01, p= 0.92). Although the physiological mechanisms to which exercise benefits domain-specific cognition remain unclear, shorter bouts of walking may immediately improve visuospatial memory in this population.","cbCaid7DMwuDA3Zk","https://ap.wps.com/l/cbCaid7DMwuDA3Zk","pdf",53980,"English","# Study background\n## Rationale for short walking bouts\n# Methods\n## Participants and randomization\n## Cognitive assessments\n# Results\n## Visuospatial memory effects\n## Null effects on processing speed and visual memory\n# Discussion\n## Immediate benefits and open mechanisms","[{\"question\":\"Why focus on short bouts of walking after knee replacement?\",\"answer\":\"Adults with TKR often remain physically inactive, and longer activity may be difficult due to reduced functioning. The study tests whether a shorter bout could be more feasible while lowering risk related to ADRD.\"},{\"question\":\"How was cognition measured in the study?\",\"answer\":\"Cognition was assessed with brief phone-based tests at baseline and immediately after each period. Symbol search measured processing speed, grid memory measured visuospatial memory, and color shapes measured visual memory.\"},{\"question\":\"What cognitive domain improved after a 6-minute walk?\",\"answer\":\"The 6-minute walk was associated with improved visuospatial memory, shown by shorter error distances on the grid memory test.\"},{\"question\":\"Did walking also improve processing speed or visual memory?\",\"answer\":\"No. The walking effect was not observed for processing speed or visual memory based on the reported model estimates and p-values.\"}]","Acute Effects of a Short Bout of Walking on Domain-Specific Cognition in Adults With Knee Replacement - Poster Session | PDF",1790634378]