[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-433448-105":59,"doc-detail-433448-en":131},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":124,"head_meta":126,"extra_data":128,"updated_unix":130},105,"en","acquired-cystic-disease-associated-renal-cell-carcinoma-a-case-report-clinical-guidance","Acquired cystic disease-associated renal cell carcinoma - a case report - Clinical guidance","","Acquired cystic disease-associated renal cell carcinoma (ACD-RCC) is an uncommon renal tumor occurring mainly in patients with long-term dialysis and end-stage renal disease. This case report describes an elderly male with a 13-year dialysis history who presented with two weeks of hematuria. Surgical pathology confirmed ACD-RCC, with characteristic oxalate crystal features and immunohistochemical marker expression. The discussion emphasizes imaging surveillance and early pathological assessment, enabling prompt intervention to improve prognosis and life quality.",{"@graph":69,"@context":123},[70,84,106],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/acquired-cystic-disease-associated-renal-cell-carcinoma-a-case-report-clinical-guidance/433448/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/acquired-cystic-disease-associated-renal-cell-carcinoma-a-case-report-clinical-guidance/433448.png","ImageObject",300,407,{"name":92,"@type":93},"pixelkiddo","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-31","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":105},"InteractionCounter",{"@type":104},"ViewAction",11,{"@type":107,"mainEntity":108},"FAQPage",[109,115,119],{"name":110,"@type":111,"acceptedAnswer":112},"Who is at higher risk for ACD-RCC according to the report?","Question",{"text":113,"@type":114},"ACD-RCC mainly affects patients with end-stage renal disease who have a prolonged dialysis history.","Answer",{"name":116,"@type":111,"acceptedAnswer":117},"What presentation led to diagnosis in this case?",{"text":118,"@type":114},"The patient presented with hematuria lasting for two weeks after a 13-year history of regular dialysis.",{"name":120,"@type":111,"acceptedAnswer":121},"Which diagnostic steps are emphasized after a lesion is detected?",{"text":122,"@type":114},"The report highlights prompt pathological examination to determine lesion nature, followed by early intervention to improve prognosis and life quality.","https://schema.org",{"og:url":83,"og:type":125,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":127,"canonical":83},"index,follow",{"doc_id":129,"site_id":62},433448,1790895082,{"code":4,"msg":5,"data":132},{"doc_id":129,"user_id":133,"nickname":92,"user_avatar":134,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":135,"file_id":136,"file_url":137,"file_type":138,"file_size":139,"view_count":105,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":24,"language":140,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":141,"faqs":142,"seo_title":143,"seo_description":67,"update_tm":144,"read_time":145,"preview_page_count":4},962090883892,"https://ap-avatar.wpscdn.com/avatar/e00115db34f3e0f11b?x-image-process=image/resize,m_fixed,w_180,h_180&k=1790152879550218658","Case Report  \nAcquired cystic disease-associated renal cell carcinoma: a case report  \nJiang Tao, MM, Wang Pan, MM, Zhu JunHui, MM, Li BingQuan, MM*  \nIntroduction and importance: This article presents a case study to explore the etiology, pathology, radiological features, treatment, and prognosis of acquired cystic disease-associated renal cell carcinoma (ACD-RCC) .  \nCase presentation: An elderly male patient with a 13-year history of regular dialysis due to renal failure was admitted to the hospital presenting with hematuria lasting for 2 weeks. Following surgery, a tumor was identified within the renal parenchyma, and pathological analysis confirmed the diagnosis of ACD-RCC.  \nClinical Discussion: ACD-RCC is relatively rare and characterized by distinctive clinical and pathological manifestations. This condition typically occurs in patients with prolonged dialysis history. Microscopic examination commonly reveals characteristic calcium oxalate crystals, and immunohistochemical analyses typically demonstrate the expression of specific markers such as P504S and CD10 .  \nConclusion: ACD-RCC is an extremely rare kidney tumor seen mainly in patients with end-stage renal disease. Regular imaging monitoring is crucial for long-term dialysis patients, particularly those who are young and minimally symptomatic. Upon detecting a lesion, a prompt pathological examination should be conducted to determine the lesion’s nature, followed by early intervention to improve prognosis and life quality.  \nKeywords: acquired cystic nephropathy, dialysis, renal cell carcinoma  \nIntroduction and importance  \nAcquired cystic disease-associated renal cell carcinoma (ACDRCC) represents the most common type of renal tumor inpatients with end-stage renal disease (ESRD) . Dialysis duration directly influences its incidence, underscoring its role as a primary contributing factor. According to the fifth edition (2022) of the World Health Organization (WHO) classification of renal tumors, ACD-RCC is recognized as a distinct renal tumor type. Currently, there are few studies on ACD-RCC. This paper reviews relevant literature to provide a comprehensive analysis of its etiology, pathology, radiological characteristics, treatment strategies, and prognosis. The goal is to enhance understanding and improve recognition of this uncommon form of renal cell carcinoma (RCC).This case report was prepared following the SCARE (Surgical Case report Checklist) guidelines to ensure comprehensive reporting[1] .  \nDepartment of Pathology, The Affiliated Qingyuan Hospital (Qingyuan People’s Hospital), Guangzhou Medical University, Qingyuan Guangdong, China Sponsorships or competing interests that may be relevant to content are disclosed at the end of this article.  \nJiang Tao, Wang Pan and Zhu JunHui contributed equally to this work.  \n*Corresponding author. Address: Department of Pathology, The Affiliated Qingyuan Hospital (Qingyuan People’s Hospital), Guangzhou Medical University, No. 35, Yinquan North Road, Qingcheng District, Qingyuan Guangdong 511518, China. Tel.: +86 13417289527. E-mail: [146202@qq.com](146202@qq.com) (L. BingQuan).  \nCopyright © 2025 The Author(s). Published by Wolters Kluwer Health, Inc. This is an open access article distributed under the Creative Commons Attribution-NoDerivatives License 4.0, which allows for redistribution, commercial and noncommercial, as long as it is passed along unchanged and in whole, with credit to the author.  \nAnnals of Medicine & Surgery (2026) 88:830–834  \nReceived 24 June 2025; Accepted 10 November 2025  \nPublished online 25 November 2025  \n[http://dx.doi.org/10.1097/MS9.0000000000004379](http://dx.doi.org/10.1097/MS9.0000000000004379)  \nHIGHLIGHTS  \n● Acquired cystic disease-associated renal cell carcinoma (ACD-RCC) represents the most frequent renal tumor type in patients with end-stage renal disease. Dialysis duration directly influences its incidence, underscoring its role as a primary contributing factor.  \n● ACD-RC","cbCaiaB82Zj1Hy0g","https://ap.wps.com/l/cbCaiaB82Zj1Hy0g","pdf",1172666,"English","# Introduction and importance\n# Case presentation\n## Clinical Discussion\n# Conclusion\n# Highlights","[{\"question\":\"Who is at higher risk for ACD-RCC according to the report?\",\"answer\":\"ACD-RCC mainly affects patients with end-stage renal disease who have a prolonged dialysis history.\"},{\"question\":\"What presentation led to diagnosis in this case?\",\"answer\":\"The patient presented with hematuria lasting for two weeks after a 13-year history of regular dialysis.\"},{\"question\":\"Which diagnostic steps are emphasized after a lesion is detected?\",\"answer\":\"The report highlights prompt pathological examination to determine lesion nature, followed by early intervention to improve prognosis and life quality.\"}]","Acquired cystic disease-associated renal cell carcinoma - a case report - Clinical guidance | PDF",1790664131,13]