[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"detail-sidebar-cat-0-en-105":3,"doc-seo-435627-105":59,"doc-detail-435627-en":130},{"code":4,"msg":5,"data":6},0,"success",[7,13,18,23,28,33,38,43,48,51,55],{"id":8,"doc_module":4,"doc_module_name":9,"category_name":10,"show_sort_weight":11,"slug":12},1,"Document","Story & Novel",90,"story-novel",{"id":14,"doc_module":4,"doc_module_name":9,"category_name":15,"show_sort_weight":16,"slug":17},2,"Literature",80,"literature",{"id":19,"doc_module":4,"doc_module_name":9,"category_name":20,"show_sort_weight":21,"slug":22},4,"Exam",70,"exam",{"id":24,"doc_module":4,"doc_module_name":9,"category_name":25,"show_sort_weight":26,"slug":27},5,"Comic",60,"comic",{"id":29,"doc_module":4,"doc_module_name":9,"category_name":30,"show_sort_weight":31,"slug":32},6,"Technology",50,"technology",{"id":34,"doc_module":4,"doc_module_name":9,"category_name":35,"show_sort_weight":36,"slug":37},7,"Healthcare",40,"healthcare",{"id":39,"doc_module":4,"doc_module_name":9,"category_name":40,"show_sort_weight":41,"slug":42},8,"Research & Report",30,"research-report",{"id":44,"doc_module":4,"doc_module_name":9,"category_name":45,"show_sort_weight":46,"slug":47},9,"Religion & Spirituality",20,"religion-spirituality",{"id":46,"doc_module":4,"doc_module_name":9,"category_name":49,"show_sort_weight":46,"slug":50},"World Cup","world-cup",{"id":52,"doc_module":4,"doc_module_name":9,"category_name":53,"show_sort_weight":52,"slug":54},10,"Lifestyle","lifestyle",{"id":56,"doc_module":4,"doc_module_name":9,"category_name":57,"show_sort_weight":24,"slug":58},19,"General","general",{"code":4,"msg":60,"data":61},"ok",{"site_id":62,"language":63,"slug":64,"title":65,"keywords":66,"description":67,"schema_data":68,"social_meta":123,"head_meta":125,"extra_data":127,"updated_unix":129},105,"en","achieving-breast-symmetry-in-a-patient-with-neurofibromatosis-1-a-case-report-and-literature-review","Achieving Breast Symmetry in a Patient With Neurofibromatosis-1 - A Case Report and Literature Review","","Breast deformities secondary to neurofibromatosis-1 are poorly described in the literature. This case report details the surgical management of breast asymmetry and distortion arising from chest wall and spinal neurofibromatous involvement in a 24-year-old woman. The right breast showed loss of projection, inframammary fold effacement, and caudal displacement. By suspending ptotic lower-chest tissue within the retromammary space, the team achieved autoaugmentation, improved projection, and simultaneously reinforced the inframammary fold, with slight intraoperative overcorrection. No postoperative complications occurred, and at 10 months follow-up, symmetry remained satisfactory.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/achieving-breast-symmetry-in-a-patient-with-neurofibromatosis-1-a-case-report-and-literature-review/435627/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/achieving-breast-symmetry-in-a-patient-with-neurofibromatosis-1-a-case-report-and-literature-review/435627.png","ImageObject",300,407,{"name":92,"@type":93},"OmBimo","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-11-08","2026-09-29",true,{"@type":102,"interactionType":103,"userInteractionCount":34},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What breast deformities were present in the patient with neurofibromatosis-1?","Question",{"text":112,"@type":113},"The right breast had loss of projection, effacement of the inframammary fold, and caudal displacement of the breast and nipple–areola complex.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"How did the surgical approach correct the asymmetry and deformity?",{"text":117,"@type":113},"Ptotic tissue from the lower chest was suspended in the retromammary space to induce autoaugmentation of the right breast, improve projection, and intensify the inframammary fold.",{"name":119,"@type":110,"acceptedAnswer":120},"What was the postoperative course and follow-up outcome?",{"text":121,"@type":113},"No postoperative complications were encountered. At 10-month follow-up, the patient maintained a satisfactory result with improved symmetry and high satisfaction.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},435627,1790779765,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":34,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":81,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":39,"preview_page_count":4},962090893581,"https://ap-avatar.wpscdn.com/davatar_276721f389ce27ea32af1340a28f341c","Case RepoRt   \nBreast  \nAchieving Breast Symmetry in a Patient With Neurofibromatosis-1: A Case Report and Literature Review  \nAhmed M. Hashem, MD Diwakar Phuyal, MD  \nSummary: There is limited literature describing the management of breast deformities secondary to neurofibromatosis-1 . We report the management of breast asymmetry and distortion secondary to neurofibromatosis of the chest wall and spine. A 24-year-old woman presented with breast asymmetry as a result of scoliosis, chest wall asymmetry, and soft-tissue distortion secondary to neurofibromatosis-1 . The right breast displayed loss of projection, effacement of the inframammary fold, and caudal displacement. Ptotic tissue on the right hemithorax immediately caudal to the breast was folded superiorly in the retromammary region, thereby lifting the breast upward, increasing projection via auto-augmentation, and simultaneously intensifying the inframammary fold. Slight overcorrection was accomplished intraoperatively in anticipation of potential relapse. No postoperative complications were encountered. At 10-month follow-up, the patient continued to show a satisfactory outcome with improved symmetry and was very pleased with the outcome.(Plast Reconstr Surg Glob Open 2026;14:e7371; doi: 10.1097/GOX.0000000000007371; Published online 5 January 2026.)  \nN  \neurofibromatosis-1 (NF-1) is an autosomal dominant disease secondary to mutation on chromosome 17 resulting in loss of function of neurofibromin (a  \ntumor suppressor gene), leading to uncontrolled cell proliferation and formation of neurofibromas. These nervesheath tumors arise from multiple nerves and manifest as bulging and deforming masses. Other features of NF-1 include café-au-lait macules, freckling, optic glioma, and skeletal abnormalities. Patients present with a variety of soft-tissue and bony deformities.1  \nNF-1 constitutes 96% of all neurofibromatosis (prevalence: 1 in 3000 births) .1 It is a multisystem disorder affecting skin, central and peripheral nervous systems, bones, cardiovascular system, and endocrine system.1 Neurofibromas (NF) are usually benign, slow-growing neoplasms. Nevertheless, malignant transformation has been reported in up to 13% of cases.1 In addition, patients with NF-1 have a 5 times higher risk of breast cancer, suggesting earlier screening.2 There is limited literature describing the management of breast deformities  \nFrom the Department of Plastic Surgery, Cleveland Clinic, Cleveland, OH.  \nReceived for publication July 15, 2025; accepted November 3, 2025. Copyright © 2026 The Authors. Published by Wolters Kluwer Health, Inc. on behalf of The American Society of Plastic Surgeons. This is an open-access article distributed under the terms of the Creative Commons Attribution-Non Commercial-No Derivatives License 4.0 (CCBY-NC-ND), where it is permissible to download and share the work provided it is properly cited. The work cannot be changed in any way or used commercially without permission from the journal.  \nDOI: 10. 1097/GOX.0000000000007371  \nsecondary to NF-1 . We report the management of breast asymmetry and distortion secondary to neurofibromatosis of the chest wall and spine.  \nCASE PRESENTATION  \nA 24-year-old woman with NF-1 presented with multiple café-au-lait spots, skin NFs, and scoliosis, resulting insubstantial chest wall distortion and significant breast asymmetry (Fig. 1) . Despite residual scoliosis and chest wall deformities, the orthopedic team declined further interventions. She was interested in improving the right breast appearance and symmetry. Upon clinical evaluation, she had loss of right breast projection, effacement of the right inframammary fold (IMF), and caudal displacement of the right breast and nipple–areola complex (NAC) (Fig. 1) . These deformities appeared to be secondary to her spine and chest wall misalignment and associated soft-tissue distortion. During evaluation, it was recognized that she had ptotic tissue on the lower chest. When this","cbCain6da9wNKwct","https://ap.wps.com/l/cbCain6da9wNKwct","pdf",887981,"English","# Summary\n# Background\n## Neurofibromatosis-1 and breast cancer risk\n# Case Presentation\n## Preoperative assessment\n## Surgical planning\n# Surgical Technique\n## Marking and dissection\n## Tissue suspension and closure\n# Outcome and Follow-up","[{\"question\":\"What breast deformities were present in the patient with neurofibromatosis-1?\",\"answer\":\"The right breast had loss of projection, effacement of the inframammary fold, and caudal displacement of the breast and nipple–areola complex.\"},{\"question\":\"How did the surgical approach correct the asymmetry and deformity?\",\"answer\":\"Ptotic tissue from the lower chest was suspended in the retromammary space to induce autoaugmentation of the right breast, improve projection, and intensify the inframammary fold.\"},{\"question\":\"What was the postoperative course and follow-up outcome?\",\"answer\":\"No postoperative complications were encountered. At 10-month follow-up, the patient maintained a satisfactory result with improved symmetry and high satisfaction.\"}]","Achieving Breast Symmetry in a Patient With Neurofibromatosis-1 - A Case Report and Literature Review | PDF",1790674435]