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minimize the radicality of surgery  \nSzu-Ting Yanga,b,c,d, Chia-Hao Liua,b,c,d, Peng-Hui Wanga,b,c,d,*  \naDepartment of Obstetrics and Gynecology, Taipei Veterans General Hospital, Taipei, Taiwan, ROC; bInstitute of Clinical Medicine, National Yang Ming Chiao Tung University, Taipei, Taiwan, ROC; cFemale Cancer Foundation, Taipei, Taiwan, ROC; dDepartment of Medical Research, China Medical University Hospital, Taichung, Taiwan, ROC  \nVarious kinds of malignancies have become the leading cause of death in Taiwan.1 Therefore, efforts have been made to minimize cancer-related morbidity and mortality.2 Similar to all other chronic or acute illnesses, many strategies, such as risk identification in the general population,3 healthy life style, and behavior,4,5 a cost-effective screening method,6 and an early detection7,8 for the slowing down development and/or reducing disease-related mobility and mortality have been approved effectively, although many struggles still impede to reach the satisfactory results. All need further continuous development of advanced technology and more effective therapeutic strategies to provide a better chance to prolong the life span of diseased people and minimize therapy-related adverse events (AEs) .9,10 It is always stated in the dilemma between saving lives and losing valuable organs and/ or destruction or impairment of normal function, presenting a heavy burden to patients themselves, their families, and society, and also forming the biggest challenge for both physicians and patients. However, more and more patients have re-considered their needs when they faced the diseases. Their wish is not only to focus on curing diseases uneventfully but also attempting topreserve the organ or at least maintain the function of a targeted or damaged organ eventually.  \nRegenerative medicine, organ transplantation, three-dimensional printing of custom-made prosthetic reconstructions, etc. have been reported to effectively assist in maintaining the basic or alternative function of damaged organs and/or tissue.11 However, if an accurate and precise evaluation and the following appropriate therapeutic plan can be guided before the initiation of treatment, particularly for those who are candidates suitable for surgical intervention, a minimally traumatic and/or sparing organ strategy as well as an establishment of the physiological and morphological function of damaged tissues and/or organs should be conducted to minimize the risk of overtreatmentrelated subsequent AEs and severe sequelae.11 Sometimes, no need for extra cost from new technology can be achieved,11 contributing to the refreshing or reminding of our thoughts while  \n* Address correspondence. Dr. Peng-Hui Wang, Department of Obstetricsand Gynecology, Taipei Veterans General Hospital, 201, Section 2, Shi-Pai Road, Taipei 112, Taiwan, [ROC. E-mail addresses: phwang@vghtpe.gov.tw](ROC. E-mail addresses: phwang@vghtpe.gov.tw); [pongpongwang@gmail.com](pongpongwang@gmail.com) (P.-H. Wang).  \nConflicts of interest: Dr. Peng-Hui Wang, an editorial board member at the Journal of the Chinese Medical Association, had no role in the peer review process of or decision to publish this article. The other authors declare that they have no conflicts of interest related to the subject matter or materials discussed in this article.  \nJournal of Chinese Medical Association. (2023) 86: 5-6.  \nReceived November 10, 2022; accepted November 13, 2022.  \ndoi: 10. 1097/JCMA.0000000000000849.  \nCopyright © 2022, the Chinese Medical Association. This is an open access article under the CC BY-NC-ND license ([http://creativecommons.org/licenses/](http://creativecommons.org/licenses/)[ ](http://creativecommons.org/licenses/)[by-nc-nd/4.0/](by-nc-nd/4.0/))  \nwe do more but may lose more.”12 The recent publication in the current issue of the Journal of the Chinese Medical Association entitled “Effects of nerve-sparing procedures on surgical mar","cbCaiuLG62iMu5JR","https://ap.wps.com/l/cbCaiuLG62iMu5JR","pdf",292532,"English","# Editorial overview\n## Rationale for minimizing surgical radicality\n## Regenerative and organ-preserving strategies\n## Nerve-sparing surgery in prostate cancer\n## Prognostic importance of complete tumor resection","[{\"question\":\"What is the core motivation for minimizing surgical radicality in cancer care?\",\"answer\":\"The aim is to preserve organs and maintain function while reducing therapy-related adverse events and severe sequelae, without compromising the goal of curing disease.\"},{\"question\":\"Which medical strategies are discussed as supporting organ preservation?\",\"answer\":\"The text mentions regenerative medicine, organ transplantation, and three-dimensional printing of custom-made prosthetic reconstructions, alongside improved evaluation and tailored therapeutic planning.\"},{\"question\":\"How does the editorial relate nerve-sparing procedures to surgical outcomes?\",\"answer\":\"It discusses a study in which partial nerve-sparing procedures showed a higher risk of positive surgical margins compared with complete nerve-sparing and non-nerve-sparing approaches, emphasizing site-specific effects.\"}]","A trend to minimize the radicality of surgery - Editorial | PDF",1790679443]