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The work compares transforaminal epidural steroid injection (TESI) versus percutaneous transforaminal endoscopic discectomy (PTED) in patients aged 80 and above who had conservative therapy resistance. Primary endpoints include VAS pain scores, Oswestry Disability Index, and modified MacNab outcomes, with safety assessed through operative metrics and complications across follow-ups to 12 months. 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Minimally invasive treatments such as transforaminal epidural steroid injection (TESI) and percutaneous transforaminalendoscopic discectomy (PTED) are commonly used, yet their comparative effectiveness remains unclear. This study aimed to compare the clinical outcomes, safety, and efficacy of TESI and PTED in patients aged 80 and above.\u003Cbr>Patients and Methods: : A retrospective analysis was conducted on 74 patients with conservative treatment-resistant lumbar radiculopathy. Patients were divided into TESI (n=40) and PTED (n=34) groups. Primary outcomes included Visual Analog Scale scores for back and leg pain (VAS-BP, VAS-LP), Oswestry Disability Index (ODI), and modified MacNab criteria. Secondary outcomes were operative time, fluoroscopy frequency, hospital stay, and complications. Assessments occurred preoperatively and at 1 week, 1, 3, 6, and 12 months post-procedure. Statistical analyses used ANOVA and chi-square tests.\u003Cbr>Results: Both groups showed significant short-term improvement. At 6- and 12-month follow-ups, the PTED group demonstrated superior and sustained outcomes, with greater pain reduction (VAS-BP, VAS-LP), better functional improvement (ODI), and higher excellent/good MacNab rates (87.9% vs 64.9%, p\u003C0.05) compared to TESI. The TESI group had a higher recurrence rate (21.62% vs 6.06%) . TESI was associated with shorter procedure times and hospital stays. No serious complications occurred in either group. Conclusion: Both TESI and PTED are effective minimally invasive treatments for lumbar radiculopathy in very elderly patients. TESI offers quicker procedures and rapid symptom relief, while PTED provides more durable pain reduction and functional improvement. Treatment plans should be tailored to each individual, in accordance with established geriatric care principles that emphasize the consideration of comorbid conditions, specific pathology, and patient preferences. Further prospective randomized studies are needed to confirm these results.\u003Cbr>Keywords: super elderly, lumbar radiculopathy, transforaminal epidural steroid injection, TESI, percutaneous transforaminalendoscopic discectomy, PTED, less invasive, treatment outcomes |\n| --- |\n| Introduction\u003Cbr>The aging population is a worldwide issue. According to the World Health Organization, by 2030, approximately one in six individuals globally will be 60 years or older. Additionally, the demographic of those aged 80 and above is projected to increase threefold from 2020 to 2050, reaching 426 million.1 As the population ages, there is a growing prevalence of degenerative spinal disorders, such as spinal stenosis, degenerative disc disease, and adult spinal deformities.2,3 In older |\n\nReceived: 29 September 2025  \nAccepted: 21 December 2025  \nPublished: 31 December 2025  \nClinical Interventions in Aging 2025:20 2749–2761 2749  \n© 2025 Zhou et al. This work is published and licensed by Dove Medical Press Limited. The full terms of this license are available at [https://w","cbCaieoRWfdFqEYs","https://ap.wps.com/l/cbCaieoRWfdFqEYs","pdf",3124733,13,"English","# Purpose\n# Patients and Methods\n## Outcomes and Assessments\n# Results\n# Conclusion\n# Keywords","[{\"question\":\"What treatments are compared for lumbar radiculopathy in super elderly patients?\",\"answer\":\"The study compares transforaminal epidural steroid injection (TESI) and percutaneous transforaminal endoscopic discectomy (PTED) for managing lumbar radiculopathy in patients aged 80 and above.\"},{\"question\":\"How did PTED and TESI differ in effectiveness over follow-up?\",\"answer\":\"Both treatments improved symptoms in the short term, but PTED demonstrated superior and more sustained outcomes at 6 and 12 months, including greater pain reduction, better ODI improvement, and higher excellent/good MacNab rates.\"},{\"question\":\"What were the key safety findings and recurrence trends?\",\"answer\":\"No serious complications occurred in either group. TESI had a higher recurrence rate than PTED (21.62% vs 6.06%), while TESI was associated with shorter procedure times and hospital stays.\"}]","A Retrospective Comparative Analysis of Transforaminal Epidural Steroid Injections and Percutaneous Transforaminal Endoscopic Discectomy for Managing Lumbar Radiculopathy in Super Elderly Patients | PDF",1790663863,33]