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Methods: Data from 2867 patients treated at King Saud Medical City, Riyadh were analyzed across PRBCs, FFP, platelets, and cryoprecipitate. Results: Age, hemoglobin, platelet count, and ferritin showed significant correlations with component use; hemoglobin \u003C7 g/dL triggered most PRBC transfusions. Conclusions: Tailored, evidence-based transfusion strategies can optimize blood use and reduce risk.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/a-retrospective-analysis-of-blood-component-utilization-and-transfusion-related-factors-in-a-diverse-patient-population/461800/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/a-retrospective-analysis-of-blood-component-utilization-and-transfusion-related-factors-in-a-diverse-patient-population/461800.png","ImageObject",300,407,{"name":92,"@type":93},"Patrick","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-07","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":24},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"What was the goal of this retrospective study?","Question",{"text":112,"@type":113},"To analyze blood component utilization patterns and evaluate associations between patient demographics, clinical parameters, and transfusion requirements at a tertiary care center.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"Which blood components were included in the analysis?",{"text":117,"@type":113},"Packed red blood cells (PRBCs), fresh frozen plasma (FFP), platelets, and cryoprecipitate.",{"name":119,"@type":110,"acceptedAnswer":120},"What commonly triggered PRBC transfusion?",{"text":121,"@type":113},"Hemoglobin levels below 7 g/dL were the most common trigger for PRBC transfusion.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},461800,1791094804,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":24,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":52,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144},549758146520,"https://ap-avatar.wpscdn.com/avatar/80002397d8c0411e94?_k=1775819394049821470","Article  \nA Retrospective Analysis of Blood Component Utilization and Transfusion-Related Factors in a Diverse Patient Population  \nYazeed Abdulaziz Almujali 1, Nancy Mohamed Darwish 1, Abdulqader Ali Ba Abbad 1, Hani Tamim 1,2, Muhammad Raihan Sajid 1, *, Rimah Abdullah Saleem 1, Abdulwahab Binjomah 1,3 and Kamel Aldosari 1  \nAcademic Editor: Tao-Hsin Tung  \nReceived: 10 December 2025  \nRevised: 24 December 2025  \nAccepted: 30 December 2025  \nPublished: 4 January 2026  \nCopyright: © 2026 by the authors. Licensee MDPI, Basel, Switzerland. This article is an open access article distributed under the terms and conditions of the Creative Commons Attribution (CC BY) license.  \n1 College of Medicine, Alfaisal University, Riyadh 11533, Saudi Arabia  \n2 Department of Internal Medicine, Clinical Research Institute, American University of Beirut Medical Center, Beirut P.O. Box 11-0236, Lebanon  \n3 Bacterial Diseases and Special Pathogens Department, Public Health Authority, Riyadh 13351, Saudi Arabia  \n* [Correspondence: msajid@alfaisal.edu](Correspondence: msajid@alfaisal.edu)  \nAbstract  \nBackground/Objectives: This retrospective observational study aimed to analyze blood component utilization patterns and investigate associations between patient demographics, clinical parameters, and transfusion requirements at a major tertiary care center. Methods: The study analyzed data from 2867 patients at King Saud Medical City, Riyadh. Utilization patterns and correlations were assessed for packed red blood cells (PRBCs), fresh frozen plasma (FFP), platelets, and cryoprecipitate. Results: Significant correlations were found between age, hemoglobin levels, platelet counts, ferritin levels, and transfusion of specific components. Elderly patients received more PRBCs, FFP, and platelets, while younger patients received more cryoprecipitate. Hemoglobin \u003C 7 g/dL was the most common trigger for PRBC transfusion. Platelet transfusions correlated strongly with thrombocytopenia, and elevated ferritin levels correlated with higher platelet transfusion volumes. Patients with hematologic malignancies, β-thalassemia, and sickle cell disease demonstrated distinct transfusion profiles. Conclusions: These findings underscore the importance of tailored, evidence-based transfusion strategies to optimize blood use and minimize risk.  \nKeywords: blood transfusion; demographics; clinical parameters; age; platelets; hemoglobin; packed red blood cells; fresh frozen plasma  \n1. Introduction  \nBlood products, including packed red blood cells (PRBCs), fresh frozen plasma (FFP), platelets, and cryoprecipitate, are essential in modern medicine, significantly reducing morbidity and mortality in various clinical settings. Blood transfusion plays a role in treating acute bleeding, blood loss during surgery, and blood disorders like severe anemia, leukemia, and hemophilia. It is also important for treating patients receiving chemotherapy, organ transplants, and intensive care [1] . Despite the therapeutic benefits of blood transfusion, there are possible risks that can be observed, such as immune reactions, infections, and transfusion-related acute lung injury (TRALI), which require strict regulations to ensure safety and effectiveness [2] .  \nBlood transfusions play a key role in the maintenance of hemodynamic stability and the management of various medical conditions. PRBCs, for example, are vital in improving low oxygen in tissues due to unexpected blood loss or long-term anemia due to trauma and surgery cases. However, excessive use of PRBCs could lead to serious complications,  \nincluding infections. This illustrates the importance of correct usage based on proven transfusion criteria [3] . In contrast, FFP, is essential to treat bleeding diathesis, massive transfusions, and liver disease. However, it should be used carefully to prevent edema and allergic responses [4] .  \nIn addition, platelets and cryoprecipitate are utilized in blood transfusion. For instance, plate","cbCaiofxpmUIT2eo","https://ap.wps.com/l/cbCaiofxpmUIT2eo","pdf",216606,"English","# Abstract\n# Introduction\n# Methods\n## Study Design\n## Data Collection","[{\"question\":\"What was the goal of this retrospective study?\",\"answer\":\"To analyze blood component utilization patterns and evaluate associations between patient demographics, clinical parameters, and transfusion requirements at a tertiary care center.\"},{\"question\":\"Which blood components were included in the analysis?\",\"answer\":\"Packed red blood cells (PRBCs), fresh frozen plasma (FFP), platelets, and cryoprecipitate.\"},{\"question\":\"What commonly triggered PRBC transfusion?\",\"answer\":\"Hemoglobin levels below 7 g/dL were the most common trigger for PRBC transfusion.\"}]","A Retrospective Analysis of Blood Component Utilization and Transfusion-Related Factors in a Diverse Patient Population | PDF",1790762451,25]