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Imaging showed mediastinal lymphadenopathy, bilateral subpleural nodules, and mild right pleural effusion, with PET-CT demonstrating FDG-avid lesions. Bronchoscopy found a polypoid broad-based mass; biopsy revealed non-necrotizing granulomatous inflammation without malignancy or necrosis. The lesion was removed via electrosurgical snaring with cryoextraction, microbiology was unremarkable, and oral prednisolone was started.",{"@graph":69,"@context":122},[70,84,105],{"@type":71,"itemListElement":72},"BreadcrumbList",[73,77,79,82],{"item":74,"name":75,"@type":76,"position":8},"https://docshare.wps.com","Home","ListItem",{"item":78,"name":9,"@type":76,"position":14},"https://docshare.wps.com/document/",{"item":80,"name":35,"@type":76,"position":81},"https://docshare.wps.com/document/healthcare/",3,{"item":83,"name":65,"@type":76,"position":19},"https://docshare.wps.com/document/a-rare-case-of-sarcoidosis-presenting-with-endobronchial-mass-case-report/458057/",{"url":83,"name":65,"@type":85,"image":86,"author":91,"headline":65,"publisher":94,"fileFormat":97,"inLanguage":63,"description":67,"dateModified":98,"datePublished":99,"encodingFormat":97,"isAccessibleForFree":100,"interactionStatistic":101},"DigitalDocument",{"url":87,"@type":88,"width":89,"height":90},"https://docshare.wps.com/thumbnails/a-rare-case-of-sarcoidosis-presenting-with-endobronchial-mass-case-report/458057.png","ImageObject",300,407,{"name":92,"@type":93},"Noah","Person",{"url":74,"name":95,"@type":96},"DocShare","Organization","application/pdf","2026-10-30","2026-09-30",true,{"@type":102,"interactionType":103,"userInteractionCount":52},"InteractionCounter",{"@type":104},"ViewAction",{"@type":106,"mainEntity":107},"FAQPage",[108,114,118],{"name":109,"@type":110,"acceptedAnswer":111},"Why is sarcoidosis difficult to diagnose when presenting as an endobronchial mass?","Question",{"text":112,"@type":113},"Its non-specific presentations and mass-like lesions can mimic malignancy, making diagnostic interpretation challenging.","Answer",{"name":115,"@type":110,"acceptedAnswer":116},"What did CT and PET-CT show in this case?",{"text":117,"@type":113},"CT chest revealed mediastinal lymphadenopathy, multiple small peripheral lung nodules, and mild right pleural effusion; PET-CT showed FDG-avid mediastinal lymphadenopathy and bilateral subpleural nodules.",{"name":119,"@type":110,"acceptedAnswer":120},"How was the diagnosis confirmed and what treatment was started?",{"text":121,"@type":113},"Biopsy demonstrated granulomatous inflammation with lymphoplasmacytic infiltration without necrosis or malignancy. The endobronchial mass was removed endoscopically, and the patient was started on oral prednisolone.","https://schema.org",{"og:url":83,"og:type":124,"og:title":65,"og:site_name":95,"og:description":67},"article",{"robots":126,"canonical":83},"index,follow",{"doc_id":128,"site_id":62},458057,1790795678,{"code":4,"msg":5,"data":131},{"doc_id":128,"user_id":132,"nickname":92,"user_avatar":133,"doc_module":4,"category_id":34,"category_name":35,"doc_title":65,"doc_description":67,"doc_content":134,"file_id":135,"file_url":136,"file_type":137,"file_size":138,"view_count":52,"is_deleted":4,"is_public":8,"is_downloadable":8,"audit_status":8,"page_count":29,"language":139,"language_code":63,"site_id":62,"html_lang":63,"table_of_contents":140,"faqs":141,"seo_title":142,"seo_description":67,"update_tm":143,"read_time":144,"preview_page_count":4},8796095462418,"https://ap-avatar.wpscdn.com/avatar/80000253c1241d02b47?x-image-process=image/resize,m_fixed,w_180,h_180&k=1778826106357471780","Review began 09/25/2025  \nReview ended 12/02/2025  \nPublished 12/08/2025  \n© Copyright 2025  \nG et al. This is an open access article distributed under the terms of the Creative Commons Attribution License CC-BY 4.0. , which permits unrestricted use , distribution , and reproduction in any medium , provided the original author and source are credited.  \nDOI: 10.7759/cureus.98768  \nOpen Access Case Report  \nA Rare Case of Sarcoidosis Presenting With Endobronchial Mass  \nRamachandana G 1, Pankti Sheth 1 , Viswesvaran Balasubramanian 1 , Kona Lakshmi Chermisha Naidu 1 , Ananya Reddy Aerra 2  \n1. Interventional Pulmonology, Yashoda Hospitals, Hyderabad, IND 2. Medicine, Gandhi Medical College, Hyderabad, IND  \nCorresponding author: Viswesvaran Balasubramanian, [drviswesvaran@yahoo.com](drviswesvaran@yahoo.com)  \nAbstract  \nWe report a rare case of sarcoidosis presenting with endobronchial mass in a 34-year-old male patient who presented with progressive shortness of breath and non-productive cough for one month. It is diagnostically challenging due to its non-specific presentations, as mass lesions can mimic malignancy. In this case, CT chest initially revealed mediastinal lymphadenopathy, multiple small peripheral lung nodules and mild right sided pleural effusion. Positron emission tomography (PET) CT revealed mediastinal lymphadenopathy and bilateral subpleural nodules. Bronchoscopy revealed a polypoid mass with a broad base in segmental bronchus of the right lower lobe. Histopathological examination of biopsy revealed granulomatous inflammation with lymphoplasmacytic infiltration, with no evidence of necrosis or malignancy. The endobronchial mass was removed using electrosurgical snaring with cryoextraction. Microbiological and cytology examinations were unremarkable. The patient was diagnosed with sarcoidosis and was initiated on oral prednisolone. This case highlights the importance of considering sarcoidosis in the differential diagnosis to ensure timely and appropriate management.  \nCategories: Pulmonology  \nKeywords: endobronchial mass, granulomatous inflammation, mediastinal lymphadenopathy, pet ct scan, sarcoidosis  \nIntroduction  \nSarcoidosis is a chronic, multisystemic granulomatous disease of unknown etiology that predominantly affects the lungs and characterized by the non-caseating granuloma formation in affected organs [1] . A characteristic pathology and the elimination of various infectious, interstitial and neoplastic illnesses serve as the basis for the diagnosis. Cough, dyspnea, fatigue, unintentional weight loss and night sweats are some of the symptoms observed in pulmonary sarcoidosis patients [2] . Clinical manifestations of sarcoidosis may vary according to the organ involved, ranging from asymptomatic to fatal presentations [3] . Atypical radiographic presentations of pulmonary sarcoidosis can be diagnostically challenging as the associated symptoms often resemble malignancy, particularly when rare mass lesions are present [4] . Although pulmonary involvement in sarcoidosis is common, endobronchial mass remains as a rare manifestation and it mimics malignancy [1] .  \nWe report a rare case of sarcoidosis presenting with endobronchial mass highlighting the need to consider broad differential diagnosis and comprehensive evaluation.  \nCase Presentation  \nA 34-year-old male patient, non-smoker, presented with progressive shortness of breath and nonproductive cough for the past one month. Patient denied symptoms of fever, hemoptysis, chest pain and pedal edema. There was no history of weight loss, appetite loss, or symptoms suggestive of connective tissue disease or vasculitis. His past medical and surgical history were unremarkable.  \nHe was initially evaluated at another center, where a high-resolution CT chest revealed mediastinal lymphadenopathy, multiple small peripheral lung nodules with mild right sided pleural effusion with the arrows of 1A pointing to subcarinal lymph node (LN) and 1B to subpleural n","cbCaihuB1b6W4xHD","https://ap.wps.com/l/cbCaihuB1b6W4xHD","pdf",2064019,"English","# Abstract\n# Introduction\n# Case Presentation\n# How to cite this article\n# Figures","[{\"question\":\"Why is sarcoidosis difficult to diagnose when presenting as an endobronchial mass?\",\"answer\":\"Its non-specific presentations and mass-like lesions can mimic malignancy, making diagnostic interpretation challenging.\"},{\"question\":\"What did CT and PET-CT show in this case?\",\"answer\":\"CT chest revealed mediastinal lymphadenopathy, multiple small peripheral lung nodules, and mild right pleural effusion; PET-CT showed FDG-avid mediastinal lymphadenopathy and bilateral subpleural nodules.\"},{\"question\":\"How was the diagnosis confirmed and what treatment was started?\",\"answer\":\"Biopsy demonstrated granulomatous inflammation with lymphoplasmacytic infiltration without necrosis or malignancy. The endobronchial mass was removed endoscopically, and the patient was started on oral prednisolone.\"}]","A Rare Case of Sarcoidosis Presenting With Endobronchial Mass - Case report | PDF",1790751459,15]