[{"data":1,"prerenderedAt":-1},["ShallowReactive",2],{"doc-detail-31900":3,"doc-seo-31900":27},{"code":4,"msg":5,"data":6},0,"success",{"doc_id":7,"user_id":8,"nickname":9,"user_avatar":10,"doc_module":4,"category_id":11,"category_name":12,"doc_title":13,"doc_description":14,"file_id":15,"file_url":16,"file_type":17,"file_size":18,"view_count":4,"is_deleted":4,"is_public":19,"is_downloadable":19,"audit_status":19,"page_count":20,"language":21,"language_code":22,"table_of_contents":23,"faqs":24,"seo_title":13,"seo_description":14,"update_tm":25,"read_time":26},31900,4398048949847,"Eliana","https://ap-avatar.wpscdn.com/avatar/400002536579ef2da7f?_k=1778318612642679267",8,"Research & Report","A Rapid Detection and Separation of Eugenol and Its Isomers Isolated From Polianthes tuberosa Flower by Supercritical Fluid Chromatography-Photodiode Array-Mass Spectrometry: A Method Development, Validation, and Stability Studies","Supercritical fluid chromatography (SFC) is positioned as a green alternative to normal-phase liquid chromatography, delivering rapid and efficient separations with reduced environmental impact. Rapid characterization and quantification of eugenol and its derivatives from Polianthes tuberosa flower were achieved using an SFC approach coupled to mass spectrometry (SFC-MS). The work integrates method development, validation, and stability studies, addressing gaps in absolute measurement of eugenol from this source. Molecular docking and molecular dynamics simulations were further conducted to interpret interactions of the potent eugenol isomer with biological targets.","cbCaihKVS8LS7Drw","https://ap.wps.com/l/cbCaihKVS8LS7Drw","pdf",4974085,1,14,"English","en","# Introduction\n## Chiral compounds and the need for enantiomer separation\n## Comparison of HPLC and SFC based on mobility, thermodynamics, and separation performance\n# (Article sections beyond the provided excerpt)","[{\"question\":\"Why is supercritical fluid chromatography (SFC) considered a green alternative to conventional liquid chromatography?\",\"answer\":\"SFC separations are described as quick and efficient while being environmentally friendly. Its use of supercritical CO2 with a co-solvent improves mass transfer through lower viscosity and enhanced diffusion.\"},{\"question\":\"What was the purpose of developing the SFC-MS method in this study?\",\"answer\":\"The study developed an SFC coupled with mass spectrometry approach to rapidly characterize and quantify eugenol (and related derivatives) from Polianthes tuberosa flower, including method development, validation, and stability assessment.\"},{\"question\":\"How were molecular docking and molecular dynamics simulations used in the research?\",\"answer\":\"Molecular docking and molecular dynamics simulations were performed for a potent eugenol isomer to clarify how the compound interacts with different biological targets, supporting insights relevant to drug discovery.\"}]",1780434078,35,{"code":4,"msg":28,"data":29},"ok",{"site_id":30,"language":22,"slug":31,"title":13,"keywords":32,"description":14,"schema_data":33,"social_meta":84,"head_meta":86,"extra_data":88,"updated_unix":25},105,"a-rapid-detection-and-separation-of-eugenol-and-its-isomers-isolated-from-polianthes-tuberosa-flower-by-supercritical-fluid-chromatography-photodiode-array-mass-spectrometry-a-method-development-validation-and-stability-studies","",{"@graph":34,"@context":83},[35,52,66],{"@type":36,"itemListElement":37},"BreadcrumbList",[38,42,46,49],{"item":39,"name":40,"@type":41,"position":19},"https://docshare.wps.com","Home","ListItem",{"item":43,"name":44,"@type":41,"position":45},"https://docshare.wps.com/document/","Document",2,{"item":47,"name":12,"@type":41,"position":48},"https://docshare.wps.com/document/research-report/",3,{"item":50,"name":13,"@type":41,"position":51},"https://docshare.wps.com/document/a-rapid-detection-and-separation-of-eugenol-and-its-isomers-isolated-from-polianthes-tuberosa-flower-by-supercritical-fluid-chromatography-photodiode-array-mass-spectrometry-a-method-development-validation-and-stability-studies/31900/",4,{"url":50,"name":13,"@type":53,"author":54,"headline":13,"publisher":56,"fileFormat":59,"description":14,"dateModified":60,"datePublished":60,"encodingFormat":59,"isAccessibleForFree":61,"interactionStatistic":62},"DigitalDocument",{"name":9,"@type":55},"Person",{"url":39,"name":57,"@type":58},"DocShare","Organization","application/pdf","2026-06-02",true,{"@type":63,"interactionType":64,"userInteractionCount":4},"InteractionCounter",{"@type":65},"ViewAction",{"@type":67,"mainEntity":68},"FAQPage",[69,75,79],{"name":70,"@type":71,"acceptedAnswer":72},"Why is supercritical fluid chromatography (SFC) considered a green alternative to conventional liquid chromatography?","Question",{"text":73,"@type":74},"SFC separations are described as quick and efficient while being environmentally friendly. Its use of supercritical CO2 with a co-solvent improves mass transfer through lower viscosity and enhanced diffusion.","Answer",{"name":76,"@type":71,"acceptedAnswer":77},"What was the purpose of developing the SFC-MS method in this study?",{"text":78,"@type":74},"The study developed an SFC coupled with mass spectrometry approach to rapidly characterize and quantify eugenol (and related derivatives) from Polianthes tuberosa flower, including method development, validation, and stability assessment.",{"name":80,"@type":71,"acceptedAnswer":81},"How were molecular docking and molecular dynamics simulations used in the research?",{"text":82,"@type":74},"Molecular docking and molecular dynamics simulations were performed for a potent eugenol isomer to clarify how the compound interacts with different biological targets, supporting insights relevant to drug discovery.","https://schema.org",{"og:url":50,"og:type":85,"og:title":13,"og:site_name":57,"og:description":14},"article",{"robots":87,"canonical":50},"index,follow",{"doc_id":7,"site_id":30}]